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New biologic (Ab-IPL-IL-17) for IL-17-mediated diseases: identification of the bioactive sequence (nIL-17) for IL-17A/F function.
Saviano A, Manosour AA, Raucci F, Merlino F, Marigliano N, Schettino A, Wahid M, Begum J, Filer A, Manning JE, Casillo GM, Piccolo M, Ferraro MG, Marzano S, Russomanno P, Bellavita R, Irace C, Amato J, Alfaifi M, Rimmer P, Iqbal T, Pieretti S, Vellecco V, Caso F, Costa L, Giacomelli R, Scarpa R, Cirino G, Bucci M, McGettrick HM, Grieco P, Iqbal AJ, Maione F. Saviano A, et al. Among authors: iqbal aj. Ann Rheum Dis. 2023 Nov;82(11):1415-1428. doi: 10.1136/ard-2023-224479. Epub 2023 Aug 14. Ann Rheum Dis. 2023. PMID: 37580108 Free PMC article.
Activation of GPBAR1 attenuates vascular inflammation and atherosclerosis in a mouse model of NAFLD-related cardiovascular disease.
Biagioli M, Marchianò S, Di Giorgio C, Bordoni M, Urbani G, Bellini R, Massa C, Sami Ullah Khan R, Roselli R, Chiara Monti M, Morretta E, Giordano A, Vellecco V, Bucci M, Jilani Iqbal A, Saviano A, Ab Mansour A, Ricci P, Distrutti E, Zampella A, Cieri E, Cirino G, Fiorucci S. Biagioli M, et al. Among authors: jilani iqbal a. Biochem Pharmacol. 2023 Dec;218:115900. doi: 10.1016/j.bcp.2023.115900. Epub 2023 Nov 3. Biochem Pharmacol. 2023. PMID: 37926268 Free article.
Interleukin-17 (IL-17) triggers systemic inflammation, peripheral vascular dysfunction, and related prothrombotic state in a mouse model of Alzheimer's disease.
Vellecco V, Saviano A, Raucci F, Casillo GM, Mansour AA, Panza E, Mitidieri E, Femminella GD, Ferrara N, Cirino G, Sorrentino R, Iqbal AJ, d'Emmanuele di Villa Bianca R, Bucci M, Maione F. Vellecco V, et al. Among authors: iqbal aj. Pharmacol Res. 2023 Jan;187:106595. doi: 10.1016/j.phrs.2022.106595. Epub 2022 Dec 5. Pharmacol Res. 2023. PMID: 36470548 Free article.
Anti-inflammatory and immunomodulatory activity of Mangifera indica L. reveals the modulation of COX-2/mPGES-1 axis and Th17/Treg ratio.
Saviano A, Raucci F, Casillo GM, Mansour AA, Piccolo V, Montesano C, Smimmo M, Vellecco V, Capasso G, Boscaino A, Summa V, Mascolo N, Iqbal AJ, Sorrentino R, d'Emmanuele di Villa Bianca R, Bucci M, Brancaleone V, Maione F. Saviano A, et al. Among authors: iqbal aj. Pharmacol Res. 2022 Aug;182:106283. doi: 10.1016/j.phrs.2022.106283. Epub 2022 Jun 1. Pharmacol Res. 2022. PMID: 35662629
IL-17-induced inflammation modulates the mPGES-1/PPAR-γ pathway in monocytes/macrophages.
Raucci F, Saviano A, Casillo GM, Guerra-Rodriguez M, Mansour AA, Piccolo M, Ferraro MG, Panza E, Vellecco V, Irace C, Caso F, Scarpa R, Mascolo N, Alfaifi M, Iqbal AJ, Maione F. Raucci F, et al. Among authors: iqbal aj. Br J Pharmacol. 2022 May;179(9):1857-1873. doi: 10.1111/bph.15413. Epub 2021 Mar 21. Br J Pharmacol. 2022. PMID: 33595097 Free article.
Interleukin-17A (IL-17A), a key molecule of innate and adaptive immunity, and its potential involvement in COVID-19-related thrombotic and vascular mechanisms.
Raucci F, Mansour AA, Casillo GM, Saviano A, Caso F, Scarpa R, Mascolo N, Iqbal AJ, Maione F. Raucci F, et al. Among authors: iqbal aj. Autoimmun Rev. 2020 Jul;19(7):102572. doi: 10.1016/j.autrev.2020.102572. Epub 2020 May 3. Autoimmun Rev. 2020. PMID: 32376393 Free PMC article. Review. No abstract available.
Present Status and Future Trends of Natural-Derived Compounds Targeting T Helper (Th) 17 and Microsomal Prostaglandin E Synthase-1 (mPGES-1) as Alternative Therapies for Autoimmune and Inflammatory-Based Diseases.
Saviano A, Raucci F, Casillo GM, Indolfi C, Pernice A, Foreste C, Iqbal AJ, Mascolo N, Maione F. Saviano A, et al. Among authors: iqbal aj. Molecules. 2020 Dec 18;25(24):6016. doi: 10.3390/molecules25246016. Molecules. 2020. PMID: 33353211 Free PMC article. Review.
20 results