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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1898 1
1905 1
1911 1
1915 1
1916 1
1917 1
1957 1
1966 1
1972 1
1977 3
1978 1
1979 1
1982 1
1983 1
1985 1
1986 3
1987 2
1988 2
1989 5
1990 2
1992 8
1993 2
1994 2
1995 2
1996 6
1997 6
1998 8
1999 5
2000 5
2001 12
2002 6
2003 5
2004 10
2005 17
2006 6
2007 10
2008 10
2009 12
2010 15
2011 18
2012 15
2013 22
2014 34
2015 28
2016 21
2017 28
2018 29
2019 33
2020 41
2021 39
2022 49
2023 50
2024 20

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533 results

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Page 1
Acute Diverticulitis Management.
Ellison DL. Ellison DL. Crit Care Nurs Clin North Am. 2018 Mar;30(1):67-74. doi: 10.1016/j.cnc.2017.10.006. Epub 2017 Nov 29. Crit Care Nurs Clin North Am. 2018. PMID: 29413216 Review.
This disease is the third most common gastrointestinal illness that requires hospitalization and the leading indication for elective colon resection. Abdominal pain is the most common complaint in patients with acute diverticulitis. ...
This disease is the third most common gastrointestinal illness that requires hospitalization and the leading indication for elective colo …
Acute Colonic Pseudo-Obstruction.
Arthur T, Burgess A. Arthur T, et al. Clin Colon Rectal Surg. 2022 Aug 12;35(3):221-226. doi: 10.1055/s-0041-1740044. eCollection 2022 May. Clin Colon Rectal Surg. 2022. PMID: 35966377 Free PMC article. Review.
Acute colonic pseudo-obstruction (ACPO) is a functional disorder of the large intestine distinguished by colonic dysmotility resulting in colonic distension in the absence of mechanical obstruction. ...For these patients who are difficult to manage, an underl …
Acute colonic pseudo-obstruction (ACPO) is a functional disorder of the large intestine distinguished by colonic dysmotility r …
Fruquintinib versus placebo in patients with refractory metastatic colorectal cancer (FRESCO-2): an international, multicentre, randomised, double-blind, phase 3 study.
Dasari A, Lonardi S, Garcia-Carbonero R, Elez E, Yoshino T, Sobrero A, Yao J, García-Alfonso P, Kocsis J, Cubillo Gracian A, Sartore-Bianchi A, Satoh T, Randrian V, Tomasek J, Chong G, Paulson AS, Masuishi T, Jones J, Csőszi T, Cremolini C, Ghiringhelli F, Shergill A, Hochster HS, Krauss J, Bassam A, Ducreux M, Elme A, Faugeras L, Kasper S, Van Cutsem E, Arnold D, Nanda S, Yang Z, Schelman WR, Kania M, Tabernero J, Eng C; FRESCO-2 Study Investigators. Dasari A, et al. Lancet. 2023 Jul 1;402(10395):41-53. doi: 10.1016/S0140-6736(23)00772-9. Epub 2023 Jun 15. Lancet. 2023. PMID: 37331369 Clinical Trial.
Characteristics of Early-Onset vs Late-Onset Colorectal Cancer: A Review.
REACCT Collaborative; Zaborowski AM, Abdile A, Adamina M, Aigner F, d'Allens L, Allmer C, Álvarez A, Anula R, Andric M, Atallah S, Bach S, Bala M, Barussaud M, Bausys A, Bebington B, Beggs A, Bellolio F, Bennett MR, Berdinskikh A, Bevan V, Biondo S, Bislenghi G, Bludau M, Boutall A, Brouwer N, Brown C, Bruns C, Buchanan DD, Buchwald P, Burger JWA, Burlov N, Campanelli M, Capdepont M, Carvello M, Chew HH, Christoforidis D, Clark D, Climent M, Cologne KG, Contreras T, Croner R, Daniels IR, Dapri G, Davies J, Delrio P, Denost Q, Deutsch M, Dias A, D'Hoore A, Drozdov E, Duek D, Dunlop M, Dziki A, Edmundson A, Efetov S, El-Hussuna A, Elliot B, Emile S, Espin E, Evans M, Faes S, Faiz O, Fleming F, Foppa C, Fowler G, Frasson M, Figueiredo N, Forgan T, Frizelle F, Gadaev S, Gellona J, Glyn T, Gong J, Goran B, Greenwood E, Guren MG, Guillon S, Gutlic I, Hahnloser D, Hampel H, Hanly A, Hasegawa H, Iversen LH, Hill A, Hill J, Hoch J, Hoffmeister M, Hompes R, Hurtado L, Iaquinandi F, Imbrasaite U, Islam R, Jafari MD, Kanemitsu Y, Karachun A, Karimuddin AA, Keller DS, Kelly J, Kennelly R, Khrykov G, Kocian P, Koh C, Kok N, Knight KA, Knol J, Kontovounisios C, Korner H, Krivokapic Z, Kronberger… See abstract for full author list ➔ REACCT Collaborative, et al. JAMA Surg. 2021 Sep 1;156(9):865-874. doi: 10.1001/jamasurg.2021.2380. JAMA Surg. 2021. PMID: 34190968 Review.
OBSERVATIONS: Within the next decade, it is estimated that 1 in 10 colon cancers and 1 in 4 rectal cancers will be diagnosed in adults younger than 50 years. ...The full spectrum of germline and somatic sequence variations implicated remains unknown. Younger patients typic …
OBSERVATIONS: Within the next decade, it is estimated that 1 in 10 colon cancers and 1 in 4 rectal cancers will be diagnosed in adult …
Reversal of indoleamine 2,3-dioxygenase-mediated cancer immune suppression by systemic kynurenine depletion with a therapeutic enzyme.
Triplett TA, Garrison KC, Marshall N, Donkor M, Blazeck J, Lamb C, Qerqez A, Dekker JD, Tanno Y, Lu WC, Karamitros CS, Ford K, Tan B, Zhang XM, McGovern K, Coma S, Kumada Y, Yamany MS, Sentandreu E, Fromm G, Tiziani S, Schreiber TH, Manfredi M, Ehrlich LIR, Stone E, Georgiou G. Triplett TA, et al. Nat Biotechnol. 2018 Sep;36(8):758-764. doi: 10.1038/nbt.4180. Epub 2018 Jul 16. Nat Biotechnol. 2018. PMID: 30010674 Free PMC article.
We show that PEG-KYNase administration had substantial therapeutic effects when combined with approved checkpoint inhibitors or with a cancer vaccine for the treatment of large B16-F10 melanoma, 4T1 breast carcinoma or CT26 colon carcinoma tumors. PEG-KYNase mediated prolo …
We show that PEG-KYNase administration had substantial therapeutic effects when combined with approved checkpoint inhibitors or with a cance …
TCF-1 limits intraepithelial lymphocyte antitumor immunity in colorectal carcinoma.
Yakou MH, Ghilas S, Tran K, Liao Y, Afshar-Sterle S, Kumari A, Schmid K, Dijkstra C, Inguanti C, Ostrouska S, Wilcox J, Smith M, Parathan P, Allam A, Xue HH, Belz GT, Mariadason JM, Behren A, Drummond GR, Ruscher R, Williams DS, Pal B, Shi W, Ernst M, Raghu D, Mielke LA. Yakou MH, et al. Sci Immunol. 2023 Oct 13;8(88):eadf2163. doi: 10.1126/sciimmunol.adf2163. Epub 2023 Oct 6. Sci Immunol. 2023. PMID: 37801516
Targeted deletion of TCF-1 in gammadelta T-IELs induced a distinct effector profile and reduced colon tumor formation in mice. In addition, TCF-1 expression was significantly reduced in gammadelta T-IELs present in human colorectal cancers (CRCs) compared with normal healt …
Targeted deletion of TCF-1 in gammadelta T-IELs induced a distinct effector profile and reduced colon tumor formation in mice. In add …
ScRNA-seq defines dynamic T-cell subsets in longitudinal colon and peripheral blood samples in immune checkpoint inhibitor-induced colitis.
Mann JE, Lucca L, Austin MR, Merkin RD, Robert ME, Al Bawardy B, Raddassi K, Aizenbud L, Joshi NS, Hafler DA, Abraham C, Herold KC, Kluger HM. Mann JE, et al. J Immunother Cancer. 2023 Aug;11(8):e007358. doi: 10.1136/jitc-2023-007358. J Immunother Cancer. 2023. PMID: 37586769 Free PMC article.
Checkpoint inhibitor induced colitis (ICI-colitis) is a common toxicity for which the underlying mechanisms are poorly defined. To better understand the changing colon-specific and peripheral immune environments over the course of progression and treatment of colitis, we c …
Checkpoint inhibitor induced colitis (ICI-colitis) is a common toxicity for which the underlying mechanisms are poorly defined. To better un …
Acss2/HIF-2 signaling facilitates colon cancer growth and metastasis.
Garcia JA, Chen R, Xu M, Comerford SA, Hammer RE, Melton SD, Feagins LA. Garcia JA, et al. PLoS One. 2023 Mar 2;18(3):e0282223. doi: 10.1371/journal.pone.0282223. eCollection 2023. PLoS One. 2023. PMID: 36862715 Free PMC article.
We reasoned that colon cancer cells, like fibrosarcoma cells, may respond to acetate in a pro-growth manner. ...Targeted inhibition of Acss2/HIF-2 signaling may have synergistic effects for some colon cancer patients....
We reasoned that colon cancer cells, like fibrosarcoma cells, may respond to acetate in a pro-growth manner. ...Targeted inhibition o …
Diet-derived metabolites and mucus link the gut microbiome to fever after cytotoxic cancer treatment.
Schwabkey ZI, Wiesnoski DH, Chang CC, Tsai WB, Pham D, Ahmed SS, Hayase T, Ortega Turrubiates MR, El-Himri RK, Sanchez CA, Hayase E, Frenk Oquendo AC, Miyama T, Halsey TM, Heckel BE, Brown AN, Jin Y, Raybaud M, Prasad R, Flores I, McDaniel L, Chapa V, Lorenzi PL, Warmoes MO, Tan L, Swennes AG, Fowler S, Conner M, McHugh K, Graf T, Jensen VB, Peterson CB, Do KA, Zhang L, Shi Y, Wang Y, Galloway-Pena JR, Okhuysen PC, Daniel-MacDougall CR, Shono Y, Burgos da Silva M, Peled JU, van den Brink MRM, Ajami N, Wargo JA, Reddy P, Valdivia RH, Davey L, Rondon G, Srour SA, Mehta RS, Alousi AM, Shpall EJ, Champlin RE, Shelburne SA, Molldrem JJ, Jamal MA, Karmouch JL, Jenq RR. Schwabkey ZI, et al. Sci Transl Med. 2022 Nov 16;14(671):eabo3445. doi: 10.1126/scitranslmed.abo3445. Epub 2022 Nov 16. Sci Transl Med. 2022. PMID: 36383683 Free PMC article.
Two therapies that induce neutropenia, irradiation and melphalan, similarly expanded A. muciniphila and additionally thinned the colonic mucus layer in mice. Caloric restriction of unirradiated mice also expanded A. muciniphila and thinned the colonic mucus layer. . …
Two therapies that induce neutropenia, irradiation and melphalan, similarly expanded A. muciniphila and additionally thinned the colonic …
533 results