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An allosteric inhibitor of RhoGAP class-IX myosins suppresses the metastatic features of cancer cells.
Kyriazi D, Voth L, Bader A, Ewert W, Gerlach J, Elfrink K, Franz P, Tsap MI, Schirmer B, Damiano-Guercio J, Hartmann FK, Plenge M, Salari A, Schöttelndreier D, Strienke K, Bresch N, Salinas C, Gutzeit HO, Schaumann N, Hussein K, Bähre H, Brüsch I, Claus P, Neumann D, Taft MH, Shcherbata HR, Ngezahayo A, Bähler M, Amiri M, Knölker HJ, Preller M, Tsiavaliaris G. Kyriazi D, et al. Among authors: schirmer b. Nat Commun. 2024 Nov 16;15(1):9947. doi: 10.1038/s41467-024-54181-6. Nat Commun. 2024. PMID: 39550360 Free PMC article.
Problems associated with the use of the term "antibiotics".
Seifert R, Schirmer B. Seifert R, et al. Among authors: schirmer b. Naunyn Schmiedebergs Arch Pharmacol. 2021 Nov;394(11):2153-2166. doi: 10.1007/s00210-021-02144-9. Epub 2021 Sep 18. Naunyn Schmiedebergs Arch Pharmacol. 2021. PMID: 34536087 Free PMC article. Review.
cCMP and cUMP come into the spotlight, finally.
Seifert R, Schirmer B. Seifert R, et al. Among authors: schirmer b. Trends Biochem Sci. 2022 Jun;47(6):461-463. doi: 10.1016/j.tibs.2021.12.008. Epub 2022 Jan 11. Trends Biochem Sci. 2022. PMID: 35031198
How pharmacology can aid in the diagnosis of mental disorders.
Seifert R, Schirmer B, Seifert J. Seifert R, et al. Among authors: schirmer b. Naunyn Schmiedebergs Arch Pharmacol. 2025 Feb;398(2):1099-1110. doi: 10.1007/s00210-024-03413-z. Epub 2024 Sep 4. Naunyn Schmiedebergs Arch Pharmacol. 2025. PMID: 39230588 Free PMC article. Review.
A simple mechanistic terminology of psychoactive drugs: a proposal.
Seifert R, Schirmer B. Seifert R, et al. Among authors: schirmer b. Naunyn Schmiedebergs Arch Pharmacol. 2020 Aug;393(8):1331-1339. doi: 10.1007/s00210-020-01918-x. Epub 2020 Jun 13. Naunyn Schmiedebergs Arch Pharmacol. 2020. PMID: 32535698 Free PMC article. Review.
cCMP and cUMP occur in vivo.
Bähre H, Hartwig C, Munder A, Wolter S, Stelzer T, Schirmer B, Beckert U, Frank DW, Tümmler B, Kaever V, Seifert R. Bähre H, et al. Among authors: schirmer b. Biochem Biophys Res Commun. 2015 May 15;460(4):909-14. doi: 10.1016/j.bbrc.2015.03.115. Epub 2015 Mar 31. Biochem Biophys Res Commun. 2015. PMID: 25838203 Free PMC article.
A case to stop the use of the term 'antibiotics'.
Seifert R, Schirmer B. Seifert R, et al. Among authors: schirmer b. Trends Microbiol. 2021 Nov;29(11):963-966. doi: 10.1016/j.tim.2021.03.017. Epub 2021 Apr 22. Trends Microbiol. 2021. PMID: 33895061
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