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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1989 1
1991 1
1993 2
1994 1
1998 2
2001 4
2003 1
2004 3
2005 1
2006 1
2007 5
2008 5
2009 1
2010 2
2011 1
2012 2
2013 2
2014 4
2016 3
2017 4
2018 4
2019 3
2020 7
2021 7
2022 4
2023 4
2024 2

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71 results

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The following terms were not found in PubMed: 20Vazquez
Page 1
Discussing do-not-resuscitate status.
von Gunten CF. von Gunten CF. J Clin Oncol. 2003 May 1;21(9 Suppl):20s-25s. doi: 10.1200/JCO.2003.01.159. J Clin Oncol. 2003. PMID: 12743182 No abstract available.
Advances in and applications of proteasome inhibitors.
Moore BS, Eustáquio AS, McGlinchey RP. Moore BS, et al. Curr Opin Chem Biol. 2008 Aug;12(4):434-40. doi: 10.1016/j.cbpa.2008.06.033. Epub 2008 Jul 24. Curr Opin Chem Biol. 2008. PMID: 18656549 Free PMC article. Review.
Drug discovery programs in academia and the pharmaceutical industry have developed a range of low nanomolar synthetic and natural inhibitors of the 20S proteasome core particle that have entered human clinical trials as significant anti-cancer and anti-inflammatory leads. …
Drug discovery programs in academia and the pharmaceutical industry have developed a range of low nanomolar synthetic and natural inhibitors …
An Interdisciplinary Approach to Optimize the Care of Transitioning Adolescents and Young Adults with CKD.
Diaz-Gonzalez de Ferris ME, Díaz-González de Martínez ML, Díaz-González de Velázquez AM, Díaz-González Borja A, Díaz-González Borja A, Filler G, Alvarez-Elías AC, Díaz-González Borja V. Diaz-Gonzalez de Ferris ME, et al. Blood Purif. 2021;50(4-5):684-695. doi: 10.1159/000513520. Epub 2021 Mar 11. Blood Purif. 2021. PMID: 33706317 Free article. Review.
With their continuously improved survival, AYAs must start preparation for health-care transition (HCT) from pediatric- to adult-focused health care in the pediatric setting and it must continue at the adult-focused setting, given that their brain maturation and self-management s …
With their continuously improved survival, AYAs must start preparation for health-care transition (HCT) from pediatric- to adult-focused hea …
Breath-holding as a novel approach to risk stratification in COVID-19.
Messineo L, Perger E, Corda L, Joosten SA, Fanfulla F, Pedroni L, Terrill PI, Lombardi C, Wellman A, Hamilton GS, Malhotra A, Vailati G, Parati G, Sands SA. Messineo L, et al. Crit Care. 2021 Jun 14;25(1):208. doi: 10.1186/s13054-021-03630-5. Crit Care. 2021. PMID: 34127052 Free PMC article.
Discovery of Novel Quinoline-Based Proteasome Inhibitors for Human African Trypanosomiasis (HAT).
Koester DC, Marx VM, Williams S, Jiricek J, Dauphinais M, René O, Miller SL, Zhang L, Patra D, Chen YL, Cheung H, Gable J, Lakshminarayana SB, Osborne C, Galarneau JR, Kulkarni U, Richmond W, Bretz A, Xiao L, Supek F, Wiesmann C, Honnappa S, Be C, Mäser P, Kaiser M, Ritchie R, Barrett MP, Diagana TT, Sarko C, Rao SPS. Koester DC, et al. J Med Chem. 2022 Sep 8;65(17):11776-11787. doi: 10.1021/acs.jmedchem.2c00791. Epub 2022 Aug 22. J Med Chem. 2022. PMID: 35993839 Free PMC article.
In this study, we present a brain-penetrant, parasite-selective 20S proteasome inhibitor that was rapidly optimized from an HTS singleton hit to drug candidate compound 7 that showed cure in a stage II mouse efficacy model. ...
In this study, we present a brain-penetrant, parasite-selective 20S proteasome inhibitor that was rapidly optimized from an HTS singl …
20S Proteasome as a Drug Target in Trichomonas vaginalis.
O'Donoghue AJ, Bibo-Verdugo B, Miyamoto Y, Wang SC, Yang JZ, Zuill DE, Matsuka S, Jiang Z, Almaliti J, Caffrey CR, Gerwick WH, Eckmann L. O'Donoghue AJ, et al. Antimicrob Agents Chemother. 2019 Oct 22;63(11):e00448-19. doi: 10.1128/AAC.00448-19. Print 2019 Nov. Antimicrob Agents Chemother. 2019. PMID: 31451503 Free PMC article.
Political Party Identification and Romantic Relationship Quality.
Fangmeier TL, Stanley SM, Knopp K, Rhoades GK. Fangmeier TL, et al. Couple Family Psychol. 2020 Sep;9(3):167-180. doi: 10.1037/cfp0000141. Epub 2020 Jun 25. Couple Family Psychol. 2020. PMID: 34249472 Free PMC article.
We used a national (U.S.) sample of individuals (N = 510) in their 20s and 30s who were mostly in different-sex, serious relationships (Mdn duration = 5.25 years; 50% married). ...
We used a national (U.S.) sample of individuals (N = 510) in their 20s and 30s who were mostly in different-sex, serious relationship …
Nodular Syphilis Seen in an HIV-Positive Man: A Case Study.
Burchak A, Rivera R, Douglas M. Burchak A, et al. Mil Med. 2023 Apr 12:usad066. doi: 10.1093/milmed/usad066. Online ahead of print. Mil Med. 2023. PMID: 37042677
This rise in cases is particularly relevant in military medicine as the greatest increase in cases is among adults in their 20s. Nodular syphilis is a rare presentation of the secondary stage of syphilis, and contrary to the well-known maculopapular rash seen with syphilis …
This rise in cases is particularly relevant in military medicine as the greatest increase in cases is among adults in their 20s. Nodu …
Structural elucidation of recombinant Trichomonas vaginalis 20S proteasome bound to covalent inhibitors.
Silhan J, Fajtova P, Bartosova J, Hurysz BM, Almaliti J, Miyamoto Y, Eckmann L, Gerwick WH, O'Donoghue AJ, Boura E. Silhan J, et al. bioRxiv [Preprint]. 2023 Aug 17:2023.08.17.553660. doi: 10.1101/2023.08.17.553660. bioRxiv. 2023. PMID: 37645851 Free PMC article. Preprint.
Proteasomes are essential for protein homeostasis in mammalian cells(1-4) and in protozoan parasites such as Trichomonas vaginalis (Tv).(5) Tv and other protozoan 20S proteasomes have been validated as druggable targets.(6-8) However, in the case of Tv 20S proteasom …
Proteasomes are essential for protein homeostasis in mammalian cells(1-4) and in protozoan parasites such as Trichomonas vaginalis (Tv).(5) …
71 results