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Tandem-Cleavage Linkers Improve the In Vivo Stability and Tolerability of Antibody-Drug Conjugates.
Bioconjug Chem. 2021 Apr 21;32(4):746-754. doi: 10.1021/acs.bioconjchem.1c00029. Epub 2021 Mar 9.
Bioconjug Chem. 2021.
PMID: 33689309
Free article.
Systematic LC/MS/MS Investigations for the IND-Enabling Extended Characterization of Antibody-Drug Conjugate Modifications.
Linz T, Yeo D, Hong Q, Zmolek W, McFarland J, Barfield RM, Haskins WE, Rabuka D.
Linz T, et al. Among authors: yeo d.
Antibodies (Basel). 2018 Nov 16;7(4):40. doi: 10.3390/antib7040040.
Antibodies (Basel). 2018.
PMID: 31544890
Free PMC article.
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A Novel HER2-targeted Antibody-drug Conjugate Offers the Possibility of Clinical Dosing at Trastuzumab-equivalent Exposure Levels.
Barfield RM, Kim YC, Chuprakov S, Zhang F, Bauzon M, Ogunkoya AO, Yeo D, Hickle C, Pegram MD, Rabuka D, Drake PM.
Barfield RM, et al. Among authors: yeo d.
Mol Cancer Ther. 2020 Sep;19(9):1866-1874. doi: 10.1158/1535-7163.MCT-20-0190. Epub 2020 Jul 10.
Mol Cancer Ther. 2020.
PMID: 32651200
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