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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 2
2003 7
2004 3
2005 4
2006 11
2007 4
2008 7
2009 14
2010 14
2011 12
2012 15
2013 30
2014 38
2015 19
2016 37
2017 51
2018 43
2019 37
2020 51
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Search Results

364 results
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Page 1
Structure of Mpro from SARS-CoV-2 and discovery of its inhibitors.
Jin Z, Du X, Xu Y, Deng Y, Liu M, Zhao Y, Zhang B, Li X, Zhang L, Peng C, Duan Y, Yu J, Wang L, Yang K, Liu F, Jiang R, Yang X, You T, Liu X, Yang X, Bai F, Liu H, Liu X, Guddat LW, Xu W, Xiao G, Qin C, Shi Z, Jiang H, Rao Z, Yang H. Jin Z, et al. Among authors: yang h. Nature. 2020 Jun;582(7811):289-293. doi: 10.1038/s41586-020-2223-y. Epub 2020 Apr 9. Nature. 2020. PMID: 32272481
Design of wide-spectrum inhibitors targeting coronavirus main proteases.
Yang H, Xie W, Xue X, Yang K, Ma J, Liang W, Zhao Q, Zhou Z, Pei D, Ziebuhr J, Hilgenfeld R, Yuen KY, Wong L, Gao G, Chen S, Chen Z, Ma D, Bartlam M, Rao Z. Yang H, et al. PLoS Biol. 2005 Oct;3(10):e324. doi: 10.1371/journal.pbio.0030324. Epub 2005 Sep 6. PLoS Biol. 2005. PMID: 16128623 Free PMC article.
Structure of the RNA-dependent RNA polymerase from COVID-19 virus.
Gao Y, Yan L, Huang Y, Liu F, Zhao Y, Cao L, Wang T, Sun Q, Ming Z, Zhang L, Ge J, Zheng L, Zhang Y, Wang H, Zhu Y, Zhu C, Hu T, Hua T, Zhang B, Yang X, Li J, Yang H, Liu Z, Xu W, Guddat LW, Wang Q, Lou Z, Rao Z. Gao Y, et al. Among authors: yang h. Science. 2020 May 15;368(6492):779-782. doi: 10.1126/science.abb7498. Epub 2020 Apr 10. Science. 2020. PMID: 32277040 Free PMC article.
The crystal structures of severe acute respiratory syndrome virus main protease and its complex with an inhibitor.
Yang H, Yang M, Ding Y, Liu Y, Lou Z, Zhou Z, Sun L, Mo L, Ye S, Pang H, Gao GF, Anand K, Bartlam M, Hilgenfeld R, Rao Z. Yang H, et al. Proc Natl Acad Sci U S A. 2003 Nov 11;100(23):13190-5. doi: 10.1073/pnas.1835675100. Epub 2003 Oct 29. Proc Natl Acad Sci U S A. 2003. PMID: 14585926 Free PMC article.
Crystal Structures of Membrane Transporter MmpL3, an Anti-TB Drug Target.
Zhang B, Li J, Yang X, Wu L, Zhang J, Yang Y, Zhao Y, Zhang L, Yang X, Yang X, Cheng X, Liu Z, Jiang B, Jiang H, Guddat LW, Yang H, Rao Z. Zhang B, et al. Among authors: yang h. Cell. 2019 Jan 24;176(3):636-648.e13. doi: 10.1016/j.cell.2019.01.003. Cell. 2019. PMID: 30682372 Free article.
Drug design targeting the main protease, the Achilles' heel of coronaviruses.
Yang H, Bartlam M, Rao Z. Yang H, et al. Curr Pharm Des. 2006;12(35):4573-90. doi: 10.2174/138161206779010369. Curr Pharm Des. 2006. PMID: 17168763 Review.
Structural Basis for RNA Replication by the SARS-CoV-2 Polymerase.
Wang Q, Wu J, Wang H, Gao Y, Liu Q, Mu A, Ji W, Yan L, Zhu Y, Zhu C, Fang X, Yang X, Huang Y, Gao H, Liu F, Ge J, Sun Q, Yang X, Xu W, Liu Z, Yang H, Lou Z, Jiang B, Guddat LW, Gong P, Rao Z. Wang Q, et al. Among authors: yang h. Cell. 2020 Jul 23;182(2):417-428.e13. doi: 10.1016/j.cell.2020.05.034. Epub 2020 May 22. Cell. 2020. PMID: 32526208 Free PMC article.
Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease.
Dai W, Zhang B, Jiang XM, Su H, Li J, Zhao Y, Xie X, Jin Z, Peng J, Liu F, Li C, Li Y, Bai F, Wang H, Cheng X, Cen X, Hu S, Yang X, Wang J, Liu X, Xiao G, Jiang H, Rao Z, Zhang LK, Xu Y, Yang H, Liu H. Dai W, et al. Among authors: yang h. Science. 2020 Jun 19;368(6497):1331-1335. doi: 10.1126/science.abb4489. Epub 2020 Apr 22. Science. 2020. PMID: 32321856 Free PMC article.
Structural insights into substrate recognition by the type VII secretion system.
Wang S, Zhou K, Yang X, Zhang B, Zhao Y, Xiao Y, Yang X, Yang H, Guddat LW, Li J, Rao Z. Wang S, et al. Among authors: yang h. Protein Cell. 2020 Feb;11(2):124-137. doi: 10.1007/s13238-019-00671-z. Epub 2019 Nov 23. Protein Cell. 2020. PMID: 31758528 Free PMC article.
Efficient biodegradation of highly crystallized polyethylene terephthalate through cell surface display of bacterial PETase.
Chen Z, Wang Y, Cheng Y, Wang X, Tong S, Yang H, Wang Z. Chen Z, et al. Among authors: yang h. Sci Total Environ. 2020 Mar 20;709:136138. doi: 10.1016/j.scitotenv.2019.136138. Epub 2019 Dec 16. Sci Total Environ. 2020. PMID: 31887523
364 results
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