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Pyridoxal-5'-phosphate-dependent enzyme GenB3 Catalyzes C-3',4'-dideoxygenation in gentamicin biosynthesis.
Zhou S, Chen X, Ni X, Liu Y, Zhang H, Dong M, Xia H. Zhou S, et al. Microb Cell Fact. 2021 Mar 9;20(1):65. doi: 10.1186/s12934-021-01558-7. Microb Cell Fact. 2021. PMID: 33750386 Free PMC article.
RESULTS: Here, we report that GenP catalyzes 3' phosphorylation of the gentamicin biosynthesis intermediates JI-20A, JI-20Ba, and JI-20B. We further demonstrate that the pyridoxal-5'-phosphate (PLP)-dependent enzyme GenB3 uses these phosphorylated subs …
RESULTS: Here, we report that GenP catalyzes 3' phosphorylation of the gentamicin biosynthesis intermediates JI-20A, JI …
Observation of D^{+}→f_{0}(500)e^{+}ν_{e} and Improved Measurements of D→ρe^{+}ν_{e}.
Ablikim M, Achasov MN, Ahmed S, Albrecht M, Alekseev M, Amoroso A, An FF, An Q, Bai Y, Bakina O, Baldini Ferroli R, Ban Y, Begzsuren K, Bennett DW, Bennett JV, Berger N, Bertani M, Bettoni D, Bianchi F, Boger E, Boyko I, Briere RA, Cai H, Cai X, Calcaterra A, Cao GF, Cetin SA, Chai J, Chang JF, Chang WL, Chelkov G, Chen G, Chen HS, Chen JC, Chen ML, Chen PL, Chen SJ, Chen XR, Chen YB, Cheng W, Chu XK, Cibinetto G, Cossio F, Dai HL, Dai JP, Dbeyssi A, Dedovich D, Deng ZY, Denig A, Denysenko I, Destefanis M, De Mori F, Ding Y, Dong C, Dong J, Dong LY, Dong MY, Dou ZL, Du SX, Duan PF, Fang J, Fang SS, Fang Y, Farinelli R, Fava L, Fegan S, Feldbauer F, Felici G, Feng CQ, Fioravanti E, Fritsch M, Fu CD, Gao Q, Gao XL, Gao Y, Gao YG, Gao Z, Garillon B, Garzia I, Gilman A, Goetzen K, Gong L, Gong WX, Gradl W, Greco M, Gu LM, Gu MH, Gu YT, Guo AQ, Guo LB, Guo RP, Guo YP, Guskov A, Haddadi Z, Han S, Hao XQ, Harris FA, He KL, He XQ, Heinsius FH, Held T, Heng YK, Hou ZL, Hu HM, Hu JF, Hu T, Hu Y, Huang GS, Huang JS, Huang XT, Huang XZ, Huang ZL, Hussain T, Ikegami Andersson W, Irshad M, Ji Q, Ji QP, Ji XB, Ji XL, Jiang HL, Jiang XS, Jiang XY, Jiao JB, Jiao Z, Jin DP, Jin S, Jin Y, Johansson … See abstract for full author list ➔ Ablikim M, et al. Phys Rev Lett. 2019 Feb 15;122(6):062001. doi: 10.1103/PhysRevLett.122.062001. Phys Rev Lett. 2019. PMID: 30822062 Free article.
NTR 2.0: a rationally engineered prodrug-converting enzyme with substantially enhanced efficacy for targeted cell ablation.
Sharrock AV, Mulligan TS, Hall KR, Williams EM, White DT, Zhang L, Emmerich K, Matthews F, Nimmagadda S, Washington S, Le KD, Meir-Levi D, Cox OL, Saxena MT, Calof AL, Lopez-Burks ME, Lander AD, Ding D, Ji H, Ackerley DF, Mumm JS. Sharrock AV, et al. Nat Methods. 2022 Feb;19(2):205-215. doi: 10.1038/s41592-021-01364-4. Epub 2022 Feb 7. Nat Methods. 2022. PMID: 35132245 Free PMC article.
[Effect of M1 microglia-derived exosomal microRNA-20a-5p on neuronal injury after oxygen-glucose deprivation and restoration injury].
Liu W, Yin X, Wang H, Chen J, Shan K, Chen H, Zhang G, Wang M, Dong R. Liu W, et al. Zhonghua Wei Zhong Bing Ji Jiu Yi Xue. 2022 Aug;34(8):842-847. doi: 10.3760/cma.j.cn121430-20220317-00258. Zhonghua Wei Zhong Bing Ji Jiu Yi Xue. 2022. PMID: 36177928 Chinese.
Compared with group E, cell viability was decreased, apoptosis rate and the expression of miR-20a-5p were increased in group M [cell viability (A value): 0.3110.028 vs. 0.4120.029, apoptosis rate: (36.3430.761)% vs. (31.8020.647)%, miR-20a-5p (2(-deltadeltaCt)): 32. …
Compared with group E, cell viability was decreased, apoptosis rate and the expression of miR-20a-5p were increased in group M [cell …
23 results