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Page 1
Gene cloning and characterization of two NADH-dependent 3-quinuclidinone reductases from Microbacterium luteolum JCM 9174.
Appl Environ Microbiol. 2013 Feb;79(4):1378-84. doi: 10.1128/AEM.03099-12. Epub 2012 Dec 21.
Appl Environ Microbiol. 2013.
PMID: 23263947
Free PMC article.
Hybrid large hepatitis B surface protein composed of two viral genotypes C and D induces strongly cross-neutralizing antibodies.
Sanada T, Oda Y, Ohashi C, Isotani K, Goh Y, Kohara M.
Sanada T, et al. Among authors: isotani k.
Vaccine. 2023 Oct 13;41(43):6514-6521. doi: 10.1016/j.vaccine.2023.09.026. Epub 2023 Sep 20.
Vaccine. 2023.
PMID: 37739886
Free article.
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Gene-specific amplicons from metagenomes as an alternative to directed evolution for enzyme screening: a case study using phenylacetaldehyde reductases.
Itoh N, Kazama M, Takeuchi N, Isotani K, Kurokawa J.
Itoh N, et al. Among authors: isotani k.
FEBS Open Bio. 2016 May 13;6(6):566-75. doi: 10.1002/2211-5463.12067. eCollection 2016 Jun.
FEBS Open Bio. 2016.
PMID: 27419059
Free PMC article.
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Efficient synthesis of optically pure alcohols by asymmetric hydrogen-transfer biocatalysis: application of engineered enzymes in a 2-propanol-water medium.
Itoh N, Isotani K, Nakamura M, Inoue K, Isogai Y, Makino Y.
Itoh N, et al. Among authors: isotani k.
Appl Microbiol Biotechnol. 2012 Feb;93(3):1075-85. doi: 10.1007/s00253-011-3447-4. Epub 2011 Jul 8.
Appl Microbiol Biotechnol. 2012.
PMID: 21739266
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PCR-based amplification and heterologous expression of Pseudomonas alcohol dehydrogenase genes from the soil metagenome for biocatalysis.
Itoh N, Isotani K, Makino Y, Kato M, Kitayama K, Ishimota T.
Itoh N, et al. Among authors: isotani k.
Enzyme Microb Technol. 2014 Feb 5;55:140-50. doi: 10.1016/j.enzmictec.2013.10.012. Epub 2013 Nov 6.
Enzyme Microb Technol. 2014.
PMID: 24411457
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Production of (R)-3-quinuclidinol by E. coli biocatalysts possessing NADH-dependent 3-quinuclidinone reductase (QNR or bacC) from Microbacterium luteolum and Leifsonia alcohol dehydrogenase (LSADH).
Isotani K, Kurokawa J, Itoh N.
Isotani K, et al.
Int J Mol Sci. 2012 Oct 19;13(10):13542-53. doi: 10.3390/ijms131013542.
Int J Mol Sci. 2012.
PMID: 23202966
Free PMC article.
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