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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 1
2003 3
2004 1
2005 1
2007 2
2009 5
2010 9
2011 12
2012 19
2013 14
2014 10
2015 36
2016 21
2017 18
2018 21
2019 49
2020 39
2021 34
2022 49
2023 63
2024 72
2025 93
2026 59

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578 results

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Page 1
Apoptotic stress causes mtDNA release during senescence and drives the SASP.
Victorelli S, Salmonowicz H, Chapman J, Martini H, Vizioli MG, Riley JS, Cloix C, Hall-Younger E, Machado Espindola-Netto J, Jurk D, Lagnado AB, Sales Gomez L, Farr JN, Saul D, Reed R, Kelly G, Eppard M, Greaves LC, Dou Z, Pirius N, Szczepanowska K, Porritt RA, Huang H, Huang TY, Mann DA, Masuda CA, Khosla S, Dai H, Kaufmann SH, Zacharioudakis E, Gavathiotis E, LeBrasseur NK, Lei X, Sainz AG, Korolchuk VI, Adams PD, Shadel GS, Tait SWG, Passos JF. Victorelli S, et al. Among authors: lei x. Nature. 2023 Oct;622(7983):627-636. doi: 10.1038/s41586-023-06621-4. Epub 2023 Oct 11. Nature. 2023. PMID: 37821702 Free PMC article.
Mitochondrial metabolism and epigenetic crosstalk drive SASP.
Martini H, Birch J, Marques FDM, Victorelli S, Lagnado AB, Pirius N, Franco AC, Lee G, Han Y, Rowsey JL, Ismail WM, Mazzone A, Espe TM, Hitosugi T, Li Y, Washington AM, Havas A, Murad R, Lei X, Porritt RA, Maddocks ODK, Machado Espindola-Netto J, Saul D, Khosla S, Jurk D, Kostallari E, Gaspar-Maia A, Adams PD, Passos JF. Martini H, et al. Among authors: lei x. Nature. 2026 Aug;656(8129):980-992. doi: 10.1038/s41586-026-10791-2. Epub 2026 Jul 29. Nature. 2026. PMID: 42527602 Free PMC article.
Mitochondrial metabolism and epigenetic crosstalk drive the SASP.
Martini H, Birch J, Marques F, Victorelli S, Lagnado A, Pirius N, Franco A, Lee G, Han Y, Rowsey J, Gaspar-Maia A, Havas A, Murad R, Lei X, Porritt R, Maddocks O, Jurk D, Khosla S, Adams P, Passos J. Martini H, et al. Among authors: lei x. Res Sq [Preprint]. 2024 Dec 5:rs.3.rs-5278203. doi: 10.21203/rs.3.rs-5278203/v1. Res Sq. 2024. Update in: Nature. 2026 Aug;656(8129):980-992. doi: 10.1038/s41586-026-10791-2. PMID: 39678326 Free PMC article. Updated. Preprint.
Mitochondria-to-nucleus retrograde signaling drives formation of cytoplasmic chromatin and inflammation in senescence.
Vizioli MG, Liu T, Miller KN, Robertson NA, Gilroy K, Lagnado AB, Perez-Garcia A, Kiourtis C, Dasgupta N, Lei X, Kruger PJ, Nixon C, Clark W, Jurk D, Bird TG, Passos JF, Berger SL, Dou Z, Adams PD. Vizioli MG, et al. Among authors: lei x. Genes Dev. 2020 Mar 1;34(5-6):428-445. doi: 10.1101/gad.331272.119. Epub 2020 Jan 30. Genes Dev. 2020. PMID: 32001510 Free PMC article.
PSGL-1 attenuates early TCR signaling to suppress CD8+ T cell progenitor differentiation and elicit terminal CD8+ T cell exhaustion.
Hope JL, Otero DC, Bae EA, Stairiker CJ, Palete AB, Faso HA, Lin M, Henriquez ML, Roy S, Seo H, Lei X, Wang ES, Chow S, Tinoco R, Daniels GA, Yip K, Campos AR, Yin J, Adams PD, Rao A, Bradley LM. Hope JL, et al. Among authors: lei x. Cell Rep. 2023 May 30;42(5):112436. doi: 10.1016/j.celrep.2023.112436. Epub 2023 Apr 26. Cell Rep. 2023. PMID: 37115668 Free PMC article.
Author Correction: Apoptotic stress causes mtDNA release during senescence and drives the SASP.
Victorelli S, Salmonowicz H, Chapman J, Martini H, Vizioli MG, Riley JS, Cloix C, Hall-Younger E, Machado Espindola-Netto J, Jurk D, Lagnado AB, Sales Gomez L, Farr JN, Saul D, Reed R, Kelly G, Eppard M, Greaves LC, Dou Z, Pirius N, Szczepanowska K, Porritt RA, Huang H, Huang TY, Mann DA, Masuda CA, Khosla S, Dai H, Kaufmann SH, Zacharioudakis E, Gavathiotis E, LeBrasseur NK, Lei X, Sainz AG, Korolchuk VI, Adams PD, Shadel GS, Tait SWG, Passos JF. Victorelli S, et al. Among authors: lei x. Nature. 2024 Jan;625(7995):E15. doi: 10.1038/s41586-023-07002-7. Nature. 2024. PMID: 38168624 Free PMC article. No abstract available.
p53 enhances DNA repair and suppresses cytoplasmic chromatin fragments and inflammation in senescent cells.
Miller KN, Li B, Pierce-Hoffman HR, Patel S, Lei X, Rajesh A, Teneche MG, Havas AP, Gandhi A, Macip CC, Lyu J, Victorelli SG, Woo SH, Lagnado AB, LaPorta MA, Liu T, Dasgupta N, Li S, Davis A, Korotkov A, Hultenius E, Gao Z, Altman Y, Porritt RA, Garcia G, Mogler C, Seluanov A, Gorbunova V, Kaech SM, Tian X, Dou Z, Chen C, Passos JF, Adams PD. Miller KN, et al. Among authors: lei x. Nat Commun. 2025 Mar 5;16(1):2229. doi: 10.1038/s41467-025-57229-3. Nat Commun. 2025. PMID: 40044657 Free PMC article.
578 results