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Retargeted oncolytic viruses engineered to remodel the tumor microenvironment for glioblastoma immunotherapy.
Giovannoni F, Strathdee CA, Faust Akl C, Andersen BM, Li Z, Lee HG, Torti MF, Rone JM, Duart-Abadia P, Molgora M, Kong L, Floyd M, Teng J, Gyulakian Y, Grzesik P, Farkaly T, Denslow A, Feau S, Rodriguez-Sanchez I, Jacques J, Colonna M, Kennedy EM, Cheema T, Lerner L, Quéva C, Quintana FJ. Giovannoni F, et al. Nat Cancer. 2025 Dec;6(12):1994-2010. doi: 10.1038/s43018-025-01070-6. Epub 2025 Dec 4. Nat Cancer. 2025. PMID: 41345806
Automated web-based typing of Clostridioides difficile ribotypes via MALDI-TOF MS.
Blázquez-Sánchez M, Guerrero-López A, Candela A, Belenguer-Llorens A, Moreno JM, Sevilla-Salcedo C, Sánchez-Cueto M, Arroyo MJ, Gutiérrez-Pareja M, Gómez-Verdejo V, Olmos PM, Mancera L, Muñoz P, Marín M, Alcalá L, Rodríguez-Temporal D, Rodríguez-Sánchez B. Blázquez-Sánchez M, et al. BMC Bioinformatics. 2025 Jul 17;26(1):181. doi: 10.1186/s12859-025-06200-6. BMC Bioinformatics. 2025. PMID: 40676564 Free PMC article.
RESULTS: We analyzed MALDI-TOF spectra from 379 clinical isolates collected across ten Spanish hospitals and identified seven discriminant biomarker peaks. Two peaks (2463 and 4993 m/z) were uniquely associated with RT027, while combinations of five additional peaks reliab …
RESULTS: We analyzed MALDI-TOF spectra from 379 clinical isolates collected across ten Spanish hospitals and identified seven discriminant b …
Prognostic Implications of Blood Immune-Cell Composition in Metastatic Castration-Resistant Prostate Cancer.
Perez-Navarro E, Conteduca V, Funes JM, Dominguez JI, Martin-Serrano M, Cremaschi P, Fernandez-Perez MP, Gordoa TA, Font A, Vázquez-Estévez S, González-Del-Alba A, Wetterskog D, Mellado B, Fernandez-Calvo O, Méndez-Vidal MJ, Climent MA, Duran I, Gallardo E, Rodriguez Sanchez A, Santander C, Sáez MI, Puente J, Tudela J, Marinas C, López-Andreo MJ, Castellano D, Attard G, Grande E, Rosino A, Botia JA, Palma-Mendez J, De Giorgi U, Gonzalez-Billalabeitia E. Perez-Navarro E, et al. Cancers (Basel). 2024 Jul 14;16(14):2535. doi: 10.3390/cancers16142535. Cancers (Basel). 2024. PMID: 39061175 Free PMC article.
A correlative biomarker study and integrative prognostic model in chemotherapy-naïve metastatic castration-resistant prostate cancer treated with enzalutamide.
Fernandez-Perez MP, Perez-Navarro E, Alonso-Gordoa T, Conteduca V, Font A, Vázquez-Estévez S, González-Del-Alba A, Wetterskog D, Antonarakis ES, Mellado B, Fernandez-Calvo O, Méndez-Vidal MJ, Climent MA, Duran I, Gallardo E, Rodriguez Sanchez A, Santander C, Sáez MI, Puente J, Tudela J, Martínez A, López-Andreo MJ, Padilla J, Lozano R, Hervas D, Luo J, de Giorgi U, Castellano D, Attard G, Grande E, Gonzalez-Billalabeitia E. Fernandez-Perez MP, et al. Prostate. 2023 Mar;83(4):376-384. doi: 10.1002/pros.24469. Epub 2022 Dec 23. Prostate. 2023. PMID: 36564933 Free PMC article. Clinical Trial.

Plasma AR gain was strongly associated with an adverse outcome, with worse median prostate specific antigen (PSA)-PFS (4.2 vs. 14.7 m; p < 0.0001), rad-PFS (4.5 vs. 27.6 m; p < 0.0001), and OS (12.7 vs. 38.1 m; p < 0.0001). The clinical prognostic mo

…
Plasma AR gain was strongly associated with an adverse outcome, with worse median prostate specific antigen (PSA)-PFS (4.2 vs. 14.7 m …
Food industrial biowaste-based magnetic activated carbons as sustainable adsorbents for anthropogenic mercury emissions.
Rodríguez-Sánchez S, Díaz P, Ruiz B, González S, Díaz-Somoano M, Fuente E. Rodríguez-Sánchez S, et al. J Environ Manage. 2022 Jun 15;312:114897. doi: 10.1016/j.jenvman.2022.114897. Epub 2022 Mar 22. J Environ Manage. 2022. PMID: 35334399 Free article.
The resulting materials (MACs) were obtained at 220-800 C showed interesting properties: textural (SBET up to 568 m(2) g-1) and magnetic (different iron species developed), depending on the activation temperature employed. Data showed outstanding results when MACs …
The resulting materials (MACs) were obtained at 220-800 C showed interesting properties: textural (SBET up to 568 m(2) g-1) a …
The Relationship Between Alcohol Consumption With Vascular Structure and Arterial Stiffness in the Spanish Population: EVA Study.
Gonzalez-Sanchez J, Garcia-Ortiz L, Rodriguez-Sanchez E, Maderuelo-Fernandez JA, Tamayo-Morales O, Lugones-Sanchez C, Recio-Rodriguez JI, Gomez-Marcos MA; EVA Investigators. Gonzalez-Sanchez J, et al. Alcohol Clin Exp Res. 2020 Sep;44(9):1816-1824. doi: 10.1111/acer.14411. Epub 2020 Aug 9. Alcohol Clin Exp Res. 2020. PMID: 32623750
RESULTS: In the multiple regression analysis adjusted for sex, age, smoking status, and systolic blood pressure, the c-IMT and cf-PWV values of individuals drinking > 70 g/wk were higher than those of the reference group (nondrinkers) by 0.02 mm (p = 0.030) and 0.42 …
RESULTS: In the multiple regression analysis adjusted for sex, age, smoking status, and systolic blood pressure, the c-IMT and cf-PWV …
Abdominal obesity vs general obesity for identifying arterial stiffness, subclinical atherosclerosis and wave reflection in healthy, diabetics and hypertensive.
Recio-Rodriguez JI, Gomez-Marcos MA, Patino-Alonso MC, Agudo-Conde C, Rodriguez-Sanchez E, Garcia-Ortiz L; Vasorisk group. Recio-Rodriguez JI, et al. BMC Cardiovasc Disord. 2012 Feb 1;12:3. doi: 10.1186/1471-2261-12-3. BMC Cardiovasc Disord. 2012. PMID: 22292502 Free PMC article. Clinical Trial.
Arterial stiffness was assessed according to pulse wave velocity (PWV), intima-media thickness of the common carotid artery (C-IMT), augmentation index (central and peripheral), ankle-brachial index (ABI), and central and peripheral pulse pressure. RESULTS: WC and WHtR sho …
Arterial stiffness was assessed according to pulse wave velocity (PWV), intima-media thickness of the common carotid artery (C-IMT), …
Concurrent driver mutations induce distinct tumour morphologies on radiological imaging.
Rodríguez Sánchez DI, Vanneste T, Middelkoop J, Maxouri O, Rostami S, Ursprung S, Boveradze N, Chupetlovska K, Castagnoli F, Landolfi F, Hong EK, Pizzi AD, Gennaro N, Snaebjornsson P, Bodalal Z, Beets-Tan R. Rodríguez Sánchez DI, et al. Eur J Radiol. 2026 May;198:112738. doi: 10.1016/j.ejrad.2026.112738. Epub 2026 Feb 18. Eur J Radiol. 2026. PMID: 41759448 Free article.
Analysis of high-molecular-weight proteins using MALDI-TOF MS and machine learning for the differentiation of clinically relevant Clostridioides difficile ribotypes.
Candela A, Rodriguez-Temporal D, Blázquez-Sánchez M, Arroyo MJ, Marín M, Alcalá L, Bou G, Rodríguez-Sánchez B, Oviaño M. Candela A, et al. Eur J Clin Microbiol Infect Dis. 2025 Feb;44(2):417-425. doi: 10.1007/s10096-024-05023-2. Epub 2024 Dec 17. Eur J Clin Microbiol Infect Dis. 2025. PMID: 39688756
PURPOSE: Clostridioides difficile is the main cause of antibiotic related diarrhea and some ribotypes (RT), such as RT027, RT181 or RT078, are considered high risk clones. A fast and reliable approach for C. difficile ribotyping is needed for a correct clinical approach. T …
PURPOSE: Clostridioides difficile is the main cause of antibiotic related diarrhea and some ribotypes (RT), such as RT027, RT181 or RT078, a …
Dietary Polyphenol Intake is Associated with HDL-Cholesterol and A Better Profile of other Components of the Metabolic Syndrome: A PREDIMED-Plus Sub-Study.
Castro-Barquero S, Tresserra-Rimbau A, Vitelli-Storelli F, Doménech M, Salas-Salvadó J, Martín-Sánchez V, Rubín-García M, Buil-Cosiales P, Corella D, Fitó M, Romaguera D, Vioque J, Alonso-Gómez ÁM, Wärnberg J, Martínez JA, Serra-Majem L, Tinahones FJ, Lapetra J, Pintó X, Tur JA, Garcia-Rios A, García-Molina L, Delgado-Rodriguez M, Matía-Martín P, Daimiel L, Vidal J, Vázquez C, Cofán M, Romanos-Nanclares A, Becerra-Tomas N, Barragan R, Castañer O, Konieczna J, González-Palacios S, Sorto-Sánchez C, Pérez-López J, Zulet MA, Bautista-Castaño I, Casas R, Gómez-Perez AM, Santos-Lozano JM, Rodríguez-Sanchez MÁ, Julibert A, Martín-Calvo N, Hernández-Alonso P, Sorlí JV, Sanllorente A, Galmés-Panadés AM, Cases-Pérez E, Goicolea-Güemez L, Ruiz-Canela M, Babio N, Hernáez Á, Lamuela-Raventós RM, Estruch R. Castro-Barquero S, et al. Nutrients. 2020 Mar 4;12(3):689. doi: 10.3390/nu12030689. Nutrients. 2020. PMID: 32143308 Free PMC article.
Participants with body mass index (BMI) >35 kg/m(2) reported lower total polyphenol, flavonoid, and stilbene intake than those with lower BMI. ...A direct association with HDL-c was found for all subclasses except lignans and phenolic acids. To conclude, in parti …
Participants with body mass index (BMI) >35 kg/m(2) reported lower total polyphenol, flavonoid, and stilbene intake than those wit …
19 results