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Extracellular vesicles derived from umbilical cord mesenchymal stromal cells show enhanced anti-inflammatory properties via upregulation of miRNAs after pro-inflammatory priming.
Stem Cell Rev Rep. 2023 Oct;19(7):2391-2406. doi: 10.1007/s12015-023-10586-2. Epub 2023 Jul 20.
Stem Cell Rev Rep. 2023.
PMID: 37474869
Free PMC article.
Pro-Inflammatory Priming of Umbilical Cord Mesenchymal Stromal Cells Alters the Protein Cargo of Their Extracellular Vesicles.
Hyland M, Mennan C, Wilson E, Clayton A, Kehoe O.
Hyland M, et al.
Cells. 2020 Mar 16;9(3):726. doi: 10.3390/cells9030726.
Cells. 2020.
PMID: 32188006
Free PMC article.
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Therapeutic Effects of Hypoxic and Pro-Inflammatory Priming of Mesenchymal Stem Cell-Derived Extracellular Vesicles in Inflammatory Arthritis.
Kay AG, Treadwell K, Roach P, Morgan R, Lodge R, Hyland M, Piccinini AM, Forsyth NR, Kehoe O.
Kay AG, et al. Among authors: hyland m.
Int J Mol Sci. 2021 Dec 23;23(1):126. doi: 10.3390/ijms23010126.
Int J Mol Sci. 2021.
PMID: 35008555
Free PMC article.
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Syndecan-3 regulates MSC adhesion, ERK and AKT signalling in vitro and its deletion enhances MSC efficacy in a model of inflammatory arthritis in vivo.
Jones FK, Stefan A, Kay AG, Hyland M, Morgan R, Forsyth NR, Pisconti A, Kehoe O.
Jones FK, et al. Among authors: hyland m.
Sci Rep. 2020 Nov 24;10(1):20487. doi: 10.1038/s41598-020-77514-z.
Sci Rep. 2020.
PMID: 33235244
Free PMC article.
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