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Association of Blood Pressure Lowering Intensity With White Matter Network Integrity in Patients With Cerebral Small Vessel Disease.
Pflanz CP, Egle MS, O'Brien JT, Morris RG, Barrick TR, Blamire AM, Ford GA, Tozer D, Markus HS; PRESERVE study group. Pflanz CP, et al. Neurology. 2022 Oct 25;99(17):e1945-e1953. doi: 10.1212/WNL.0000000000201018. Epub 2022 Aug 17. Neurology. 2022. PMID: 35977831 Free PMC article. Clinical Trial.
TRIAL REGISTRATION INFORMATION: The trial is registered with the ISRCTN Registry (ISRCTN37694103; doi.org/10.1186/ISRCTN37694103) and the NIHR Clinical Research Network (CRN 10962; public-odp.nihr.ac.uk/QvAJAXZfc/opendoc.htm?document=crncc_users%5Cfind%20a%20clinical%20res …
TRIAL REGISTRATION INFORMATION: The trial is registered with the ISRCTN Registry (ISRCTN37694103; doi.org/10.1186/ISRCTN37694103) and the NI …
Upregulation of miR-17-92 cluster is associated with progression and lymph node metastasis in oesophageal adenocarcinoma.
Plum PS, Warnecke-Eberz U, Drebber U, Chon SH, Alakus H, Hölscher AH, Quaas A, Bruns CJ, Gockel I, Lorenz D, Metzger R, Bollschweiler E. Plum PS, et al. Sci Rep. 2019 Aug 20;9(1):12113. doi: 10.1038/s41598-019-48624-0. Sci Rep. 2019. PMID: 31431687 Free PMC article.
MicroRNA array-based quantification analysis of 754 miRs, including tumour specimens of 12 patients with pT2 OAC from three different centres (detection group), was performed. We identified miR-17, miR-19a/b, miR-20a, and miR-106a, showing the best predictive power for LNM …
MicroRNA array-based quantification analysis of 754 miRs, including tumour specimens of 12 patients with pT2 OAC from three different centre …
Changes of Microrna Levels in Plasma of Patients with Rectal Cancer during Chemoradiotherapy.
Jo P, Azizian A, Salendo J, Kramer F, Bernhardt M, Wolff HA, Gruber J, Grade M, Beißbarth T, Ghadimi BM, Gaedcke J. Jo P, et al. Int J Mol Sci. 2017 May 27;18(6):1140. doi: 10.3390/ijms18061140. Int J Mol Sci. 2017. PMID: 28554991 Free PMC article.

For 52 of the 94 patients a paired comparison between pre-treatment and post-treatment samples was performed. miR-17, miR-18b, miR-20a, miR-31, and miR-193a_3p, were significantly downregulated in pre-treatment plasma samples of patients with rectal cancer (p < 0.05). m

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For 52 of the 94 patients a paired comparison between pre-treatment and post-treatment samples was performed. miR-17, miR-18b, miR-20a …
Polymorphisms in genes of the renin-angiotensin system and cerebral small vessel disease.
Gormley K, Bevan S, Markus HS. Gormley K, et al. Cerebrovasc Dis. 2007;23(2-3):148-55. doi: 10.1159/000097052. Epub 2006 Nov 16. Cerebrovasc Dis. 2007. PMID: 17124396
RESULTS: AGT and ACE polymorphisms and haplotypes were no more common in SVD cases as a whole or the two subtypes. Amongst hypertensives only, an AGT promoter polymorphism (-20A-->C), was associated with the ILA subtype (multivariate odds ratio 1.716, 95% confidence int …
RESULTS: AGT and ACE polymorphisms and haplotypes were no more common in SVD cases as a whole or the two subtypes. Amongst hypertensives onl …