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A genome-wide investigation into the underlying genetic architecture of personality traits and overlap with psychopathology.
Gupta P, Galimberti M, Liu Y, Beck S, Wingo A, Wingo T, Adhikari K, Kranzler HR; VA Million Veteran Program; Stein MB, Gelernter J, Levey DF. Gupta P, et al. Nat Hum Behav. 2024 Nov;8(11):2235-2249. doi: 10.1038/s41562-024-01951-3. Epub 2024 Aug 12. Nat Hum Behav. 2024. PMID: 39134740 Free PMC article.
Gene-based association testing revealed 254 genes showing significant association with at least one of the five personality traits. Transcriptome-wide and proteome-wide analysis identified altered expression of genes and proteins such as CRHR1, SLC12A5, MAPT and STX4. ...
Gene-based association testing revealed 254 genes showing significant association with at least one of the five personality traits. Transcri …
Prospects for proteomics in kidney stone disease.
Vinaiphat A, Thongboonkerd V. Vinaiphat A, et al. Expert Rev Proteomics. 2017 Mar;14(3):185-187. doi: 10.1080/14789450.2017.1283222. Epub 2017 Jan 22. Expert Rev Proteomics. 2017. PMID: 28092479 No abstract available.
Aquaculture genomics, genetics and breeding in the United States: current status, challenges, and priorities for future research.
Aquaculture Genomics, Genetics and Breeding Workshop; Abdelrahman H, ElHady M, Alcivar-Warren A, Allen S, Al-Tobasei R, Bao L, Beck B, Blackburn H, Bosworth B, Buchanan J, Chappell J, Daniels W, Dong S, Dunham R, Durland E, Elaswad A, Gomez-Chiarri M, Gosh K, Guo X, Hackett P, Hanson T, Hedgecock D, Howard T, Holland L, Jackson M, Jin Y, Khalil K, Kocher T, Leeds T, Li N, Lindsey L, Liu S, Liu Z, Martin K, Novriadi R, Odin R, Palti Y, Peatman E, Proestou D, Qin G, Reading B, Rexroad C, Roberts S, Salem M, Severin A, Shi H, Shoemaker C, Stiles S, Tan S, Tang KF, Thongda W, Tiersch T, Tomasso J, Prabowo WT, Vallejo R, van der Steen H, Vo K, Waldbieser G, Wang H, Wang X, Xiang J, Yang Y, Yant R, Yuan Z, Zeng Q, Zhou T. Aquaculture Genomics, Genetics and Breeding Workshop, et al. BMC Genomics. 2017 Feb 20;18(1):191. doi: 10.1186/s12864-017-3557-1. BMC Genomics. 2017. PMID: 28219347 Free PMC article. Review.
In addition, it is also important to understand the mechanisms of regulation and evolutionary conservation at the levels of genome, transcriptome, proteome, epigenome, and systems biology. With genomic information and information between the genomes and phenomes, technolog …
In addition, it is also important to understand the mechanisms of regulation and evolutionary conservation at the levels of genome, transcri …
A protein panel in cerebrospinal fluid for diagnostic and predictive assessment of Alzheimer's disease.
Haque R, Watson CM, Liu J, Carter EK, Duong DM, Lah JJ, Wingo AP, Roberts BR, Johnson ECB, Saykin AJ, Shaw LM, Seyfried NT, Wingo TS, Levey AI. Haque R, et al. Sci Transl Med. 2023 Sep 6;15(712):eadg4122. doi: 10.1126/scitranslmed.adg4122. Epub 2023 Sep 6. Sci Transl Med. 2023. PMID: 37672565 Free PMC article.
Alzheimer's disease (AD) is a neurodegenerative disease with heterogenous pathophysiological changes that develop years before the onset of clinical symptoms. ...On the basis of our prior work integrating cerebrospinal fluid (CSF) and brain proteome networks, we dev …
Alzheimer's disease (AD) is a neurodegenerative disease with heterogenous pathophysiological changes that develop years before the on …
Integrated transcriptome and proteome analysis unveils black tea polyphenols metabolic pathways in Saccharomyces cerevisiae.
Wei Y, Chen Y, Lin X, Zhang S, Zhu B, Ji C. Wei Y, et al. Food Microbiol. 2025 Sep;130:104777. doi: 10.1016/j.fm.2025.104777. Epub 2025 Mar 10. Food Microbiol. 2025. PMID: 40210400
Firstly, profiles of polyphenols, particularly catechins were analyzed and key points of polyphenol changes kinetics were identified, then transcriptome and proteome of S. cerevisiae were examined. The overall omics data profile indicated the reduction in protein sy …
Firstly, profiles of polyphenols, particularly catechins were analyzed and key points of polyphenol changes kinetics were identified, then t …