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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1985 1
1987 1
1989 1
1994 4
1997 1
1998 1
2000 2
2001 3
2002 3
2003 4
2004 1
2005 1
2006 1
2008 3
2009 1
2010 6
2011 8
2012 1
2013 4
2014 9
2015 10
2016 5
2017 3
2018 5
2019 10
2020 6
2021 12
2022 15
2023 11
2024 8

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122 results

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Page 1
Bruton's Tyrosine Kinase Inhibition in Multiple Sclerosis.
Schneider R, Oh J. Schneider R, et al. Curr Neurol Neurosci Rep. 2022 Nov;22(11):721-734. doi: 10.1007/s11910-022-01229-z. Epub 2022 Oct 27. Curr Neurol Neurosci Rep. 2022. PMID: 36301434 Free PMC article. Review.
RECENT FINDINGS: There is evidence that some BTKIs cross the blood-brain barrier and may be superior to currently available DMTs at dampening the chronic neuroinflammatory processes compartmentalized within the CNS that contribute to progressive worsening in people withMS …
RECENT FINDINGS: There is evidence that some BTKIs cross the blood-brain barrier and may be superior to currently available DMTs at d …
Myeloid cells as potential targets for immunotherapy in pediatric gliomas.
Frederico SC, Sharma N, Darling C, Taori S, Dubinsky AC, Zhang X, Raphael I, Kohanbash G. Frederico SC, et al. Front Pediatr. 2024 Mar 8;12:1346493. doi: 10.3389/fped.2024.1346493. eCollection 2024. Front Pediatr. 2024. PMID: 38523840 Free PMC article. Review.
However, it is believed that in many pediatric glioma patients an immunosuppressive tumor microenvironment (TME) possess barriers that limit the efficacy of immune-based therapies. One of these barriers includes the presence of immunosuppressive myeloid cells. ...
However, it is believed that in many pediatric glioma patients an immunosuppressive tumor microenvironment (TME) possess barriers tha …
Current status of hepatocyte xenotransplantation.
Meier RPH, Navarro-Alvarez N, Morel P, Schuurman HJ, Strom S, Bühler LH. Meier RPH, et al. Int J Surg. 2015 Nov;23(Pt B):273-279. doi: 10.1016/j.ijsu.2015.08.077. Epub 2015 Sep 9. Int J Surg. 2015. PMID: 26361861 Free article. Review.
In this review we present an overview of the innate immune barriers in hepatocyte xenotransplantation, including the role of complement and natural antibodies; the role of phagocytic cells and ligands like CD47 in the regulation of phagocytic cells; and the role of Natural …
In this review we present an overview of the innate immune barriers in hepatocyte xenotransplantation, including the role of compleme …
Basement membrane stiffness determines metastases formation.
Reuten R, Zendehroud S, Nicolau M, Fleischhauer L, Laitala A, Kiderlen S, Nikodemus D, Wullkopf L, Nielsen SR, McNeilly S, Prein C, Rafaeva M, Schoof EM, Furtwängler B, Porse BT, Kim H, Won KJ, Sudhop S, Zornhagen KW, Suhr F, Maniati E, Pearce OMT, Koch M, Oddershede LB, Van Agtmael T, Madsen CD, Mayorca-Guiliani AE, Bloch W, Netz RR, Clausen-Schaumann H, Erler JT. Reuten R, et al. Nat Mater. 2021 Jun;20(6):892-903. doi: 10.1038/s41563-020-00894-0. Epub 2021 Jan 25. Nat Mater. 2021. PMID: 33495631 Free article.
The basement membrane (BM) is a special type of extracellular matrix and presents the major barrier cancer cells have to overcome multiple times to form metastases. Here we show that BM stiffness is a major determinant of metastases formation in several tissues and identif …
The basement membrane (BM) is a special type of extracellular matrix and presents the major barrier cancer cells have to overcome mul …
Secondary Bacterial Infections in Patients with Atopic Dermatitis or Other Common Dermatoses.
Salle R, Del Giudice P, Skayem C, Hua C, Chosidow O. Salle R, et al. Am J Clin Dermatol. 2024 Jul;25(4):623-637. doi: 10.1007/s40257-024-00856-1. Epub 2024 Apr 5. Am J Clin Dermatol. 2024. PMID: 38578398 Review.
Factors favoring secondary bacterial infections in atopic dermatitis, ectoparasitosis, and varicella zoster virus infections mainly include an epidermal barrier alteration as well as itch. Mite-bacteria interaction is also involved in scabies and some environmental factors …
Factors favoring secondary bacterial infections in atopic dermatitis, ectoparasitosis, and varicella zoster virus infections mainly include …
Recent advances in physical delivery enhancement of topical drugs.
Raphael AP, Wright OR, Benson HA, Prow TW. Raphael AP, et al. Curr Pharm Des. 2015;21(20):2830-47. doi: 10.2174/1381612821666150428144852. Curr Pharm Des. 2015. PMID: 25925114 Review.
Effective topical drug delivery into and/or through the skin is hindered by these epidermal barriers. A range of physical enhancement methods has been developed to selectively overcome this barrier. ...
Effective topical drug delivery into and/or through the skin is hindered by these epidermal barriers. A range of physical enhancement …
Translating Research into Child Health Policy: Aligning Incentives and Building a New Discourse.
Pulcini CD, Raphael JL, Lopez KN. Pulcini CD, et al. Pediatr Clin North Am. 2023 Feb;70(1):151-164. doi: 10.1016/j.pcl.2022.09.012. Pediatr Clin North Am. 2023. PMID: 36402465 Review.
However, the translation of research into child health policy has often been slow due to misalignments in incentives between researchers and policy makers and a paucity of conceptual models to inform translation. This article outlines barriers to translation, provides exam …
However, the translation of research into child health policy has often been slow due to misalignments in incentives between researchers and …
A single-cell atlas deconstructs heterogeneity across multiple models in murine traumatic brain injury and identifies novel cell-specific targets.
Jha RM, Rajasundaram D, Sneiderman C, Schlegel BT, O'Brien C, Xiong Z, Janesko-Feldman K, Trivedi R, Vagni V, Zusman BE, Catapano JS, Eberle A, Desai SM, Jadhav AP, Mihaljevic S, Miller M, Raikwar S, Rani A, Rulney J, Shahjouie S, Raphael I, Kumar A, Phuah CL, Winkler EA, Simon DW, Kochanek PM, Kohanbash G. Jha RM, et al. Neuron. 2024 Jul 11:S0896-6273(24)00456-2. doi: 10.1016/j.neuron.2024.06.021. Online ahead of print. Neuron. 2024. PMID: 39019041 Free article.
Traumatic brain injury (TBI) heterogeneity remains a critical barrier to translating therapies. Identifying final common pathways/molecular signatures that integrate this heterogeneity informs biomarker and therapeutic-target development. ...
Traumatic brain injury (TBI) heterogeneity remains a critical barrier to translating therapies. Identifying final common pathways/mol …
Cochlear pathology, sensory cell death and regeneration.
Raphael Y. Raphael Y. Br Med Bull. 2002;63:25-38. doi: 10.1093/bmb/63.1.25. Br Med Bull. 2002. PMID: 12324382 Review.
Cochlear supporting cells actively participate in the process of hair cell elimination and scar formation by rapidly expanding and sealing the reticular lamina, the barrier between endolymph and perilymph. This scarring process helps preserve the remaining hair cells and h …
Cochlear supporting cells actively participate in the process of hair cell elimination and scar formation by rapidly expanding and sealing t …
122 results