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Arginine methylation of the DDX5 helicase RGG/RG motif by PRMT5 regulates resolution of RNA:DNA hybrids.
Mersaoui SY, Yu Z, Coulombe Y, Karam M, Busatto FF, Masson JY, Richard S. Mersaoui SY, et al. Among authors: richard s. EMBO J. 2019 Aug 1;38(15):e100986. doi: 10.15252/embj.2018100986. Epub 2019 Jun 21. EMBO J. 2019. PMID: 31267554 Free PMC article.
Preventing such conflicts requires hybrid dissolution by helicases and/or RNase H. Little is known about how such helicases are regulated. Herein, we identify DDX5, an RGG/RG motif-containing DEAD-box family RNA helicase, as crucial player in R-loop resolution. ...
Preventing such conflicts requires hybrid dissolution by helicases and/or RNase H. Little is known about how such helicases are regul …
Cecal metabolome fingerprint in a rat model of decompression sickness with neurological disorders.
de Maistre S, Gaillard S, Martin JC, Richard S, Boussuges A, Rives S, Desruelle AV, Blatteau JE, Tardivel C, Risso JJ, Vallée N. de Maistre S, et al. Among authors: richard s. Sci Rep. 2020 Sep 29;10(1):15996. doi: 10.1038/s41598-020-73033-z. Sci Rep. 2020. PMID: 32994526 Free PMC article.
The effect of the diet is very marked at the metabolomic level, a little less in the blood tests, without this appearing strictly in the clinic status. ...
The effect of the diet is very marked at the metabolomic level, a little less in the blood tests, without this appearing strictly in …
Comparison of A(H3N2) neutralizing antibody responses elicited by 2018-2019 season quadrivalent influenza vaccines derived from eggs, cells, and recombinant hemagglutinin.
Wang W, Alvarado-Facundo E, Vassell R, Collins L, Colombo RE, Ganesan A, Geaney C, Hrncir D, Lalani T, Markelz AE, Maves RC, McClenathan B, Mende K, Richard SA, Schofield C, Seshadri S, Spooner C, Utz GC, Warkentien TE, Levine M, Coles CL, Burgess TH, Eichelberger M, Weiss CD. Wang W, et al. Among authors: richard sa. Clin Infect Dis. 2020 Sep 8:ciaa1352. doi: 10.1093/cid/ciaa1352. Online ahead of print. Clin Infect Dis. 2020. PMID: 32898271
BACKGROUND: Low vaccine effectiveness against A(H3N2) influenza in seasons with little antigenic drift has been attributed to substitutions in hemagglutinin (HA) acquired during vaccine virus propagation in eggs. ...
BACKGROUND: Low vaccine effectiveness against A(H3N2) influenza in seasons with little antigenic drift has been attributed to substit …
Undernutrition as an underlying cause of malaria morbidity and mortality in children less than five years old.
Caulfield LE, Richard SA, Black RE. Caulfield LE, et al. Among authors: richard sa. Am J Trop Med Hyg. 2004 Aug;71(2 Suppl):55-63. Am J Trop Med Hyg. 2004. PMID: 15331819 Review.
That undernutrition exacerbates diarrhea and respiratory infections is widely demonstrated; however, research suggests that it may exacerbate, palliate, or have little effect on malaria outcomes. This review examines the global burden of malaria associated with various nut …
That undernutrition exacerbates diarrhea and respiratory infections is widely demonstrated; however, research suggests that it may exacerbat …
Hereditary spastic paraplegia due to a novel mutation of the REEP1 gene: Case report and literature review.
Richard S, Lavie J, Banneau G, Voirand N, Lavandier K, Debouverie M. Richard S, et al. Medicine (Baltimore). 2017 Jan;96(3):e5911. doi: 10.1097/MD.0000000000005911. Medicine (Baltimore). 2017. PMID: 28099355 Free PMC article. Review.
RATIONALE: Hereditary spastic paraplegia (HSP) is a heterogeneous group of diseases little known in clinical practice due to its low prevalence, slow progression, and difficult diagnosis. ...
RATIONALE: Hereditary spastic paraplegia (HSP) is a heterogeneous group of diseases little known in clinical practice due to its low …
Biodegradable Polymeric Nanocapsules Prevent Cardiotoxicity of Anti-Trypanosomal Lychnopholide.
Branquinho RT, Roy J, Farah C, Garcia GM, Aimond F, Le Guennec JY, Saude-Guimarães DA, Grabe-Guimaraes A, Mosqueira VC, de Lana M, Richard S. Branquinho RT, et al. Among authors: richard s. Sci Rep. 2017 Mar 28;7:44998. doi: 10.1038/srep44998. Sci Rep. 2017. PMID: 28349937 Free PMC article.
Recently, a natural substance, lychnopholide, has shown therapeutic potential, especially when encapsulated in biodegradable polymeric nanocapsules. However, little is known regarding possible adverse effects of lychnopholide. ...
Recently, a natural substance, lychnopholide, has shown therapeutic potential, especially when encapsulated in biodegradable polymeric nanoc …
Stay lean without dieting: Lose Sam68.
Huot ME, Richard S. Huot ME, et al. Among authors: richard s. Adipocyte. 2012 Oct 1;1(4):246-249. doi: 10.4161/adip.20819. Adipocyte. 2012. PMID: 23700540 Free PMC article.
Although several genes have been shown to undergo alternative splicing in adipocytes, little is known about the mechanism that regulates alternative splicing during adipogenesis. ...
Although several genes have been shown to undergo alternative splicing in adipocytes, little is known about the mechanism that regula …
Sam68 Enables Metabotropic Glutamate Receptor-Dependent LTD in Distal Dendritic Regions of CA1 Hippocampal Neurons.
Klein ME, Younts TJ, Cobo CF, Buxbaum AR, Aow J, Erdjument-Bromage H, Richard S, Malinow R, Neubert TA, Singer RH, Castillo PE, Jordan BA. Klein ME, et al. Among authors: richard s. Cell Rep. 2019 Nov 12;29(7):1789-1799.e6. doi: 10.1016/j.celrep.2019.10.030. Cell Rep. 2019. PMID: 31722197 Free PMC article.
Although local translation in neuronal dendrites is now well documented, there is little evidence for corresponding effects on local synaptic function. ...
Although local translation in neuronal dendrites is now well documented, there is little evidence for corresponding effects on local …
Etiology of diarrhea in young children and patterns of antibiotic resistance in Cambodia.
Meng CY, Smith BL, Bodhidatta L, Richard SA, Vansith K, Thy B, Srijan A, Serichantalergs O, Mason CJ. Meng CY, et al. Among authors: richard sa. Pediatr Infect Dis J. 2011 Apr;30(4):331-5. doi: 10.1097/INF.0b013e3181fb6f82. Pediatr Infect Dis J. 2011. PMID: 21412204
BACKGROUND: Little is known about diarrhea etiology and antibiotic resistance in developing countries where diarrhea is a major public health problem. ...
BACKGROUND: Little is known about diarrhea etiology and antibiotic resistance in developing countries where diarrhea is a major publi …
SUMOylation negatively modulates target gene occupancy of the KDM5B, a histone lysine demethylase.
Bueno MT, Richard S. Bueno MT, et al. Among authors: richard s. Epigenetics. 2013 Nov;8(11):1162-75. doi: 10.4161/epi.26112. Epub 2013 Aug 22. Epigenetics. 2013. PMID: 23970103
KDM5B is known to regulate the expression of genes involved in cell cycle progression; however, little is known about the post-translational modifications that regulate KDM5B. ...
KDM5B is known to regulate the expression of genes involved in cell cycle progression; however, little is known about the post-transl …
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