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Recombinant human lactoferrin induces apoptosis, disruption of F-actin structure and cell cycle arrest with selective cytotoxicity on human triple negative breast cancer cells.
Iglesias-Figueroa BF, Siqueiros-Cendón TS, Gutierrez DA, Aguilera RJ, Espinoza-Sánchez EA, Arévalo-Gallegos S, Varela-Ramirez A, Rascón-Cruz Q. Iglesias-Figueroa BF, et al. Among authors: siqueiros cendon ts. Apoptosis. 2019 Aug;24(7-8):562-577. doi: 10.1007/s10495-019-01539-7. Apoptosis. 2019. PMID: 30941553
Recombinant human lactoferrin carrying humanized glycosylation exhibits antileukemia selective cytotoxicity, microfilament disruption, cell cycle arrest, and apoptosis activities.
Nakamura-Bencomo S, Gutierrez DA, Robles-Escajeda E, Iglesias-Figueroa B, Siqueiros-Cendón TS, Espinoza-Sánchez EA, Arévalo-Gallegos S, Aguilera RJ, Rascón-Cruz Q, Varela-Ramirez A. Nakamura-Bencomo S, et al. Among authors: siqueiros cendon ts. Invest New Drugs. 2021 Apr;39(2):400-415. doi: 10.1007/s10637-020-01020-2. Epub 2020 Oct 16. Invest New Drugs. 2021. PMID: 33063290