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Page 1
Molecular Tweezers: Supramolecular Hosts with Broad-Spectrum Biological Applications.
Shahpasand-Kroner H, Siddique I, Malik R, Linares GR, Ivanova MI, Ichida J, Weil T, Münch J, Sanchez-Garcia E, Klärner FG, Schrader T, Bitan G. Shahpasand-Kroner H, et al. Among authors: weil t. Pharmacol Rev. 2023 Mar;75(2):263-308. doi: 10.1124/pharmrev.122.000654. Epub 2022 Dec 22. Pharmacol Rev. 2023. PMID: 36549866 Free PMC article. Review.
Virucidal activity of SARS-CoV-2 rapid antigen extraction buffers.
Conzelmann C, Weil T, Olari LR, Gilg A, Rauch L, Albers DPJ, Groß R, Müller JA, Münch J. Conzelmann C, et al. Among authors: weil t. J Clin Virol. 2022 Feb;147:105062. doi: 10.1016/j.jcv.2021.105062. Epub 2021 Dec 27. J Clin Virol. 2022. PMID: 34995991 Free PMC article.
Native and activated antithrombin inhibits TMPRSS2 activity and SARS-CoV-2 infection.
Wettstein L, Immenschuh P, Weil T, Conzelmann C, Almeida-Hernández Y, Hoffmann M, Kempf A, Nehlmeier I, Lotke R, Petersen M, Stenger S, Kirchhoff F, Sauter D, Pöhlmann S, Sanchez-Garcia E, Münch J. Wettstein L, et al. Among authors: weil t. J Med Virol. 2023 Jan;95(1):e28124. doi: 10.1002/jmv.28124. Epub 2022 Sep 16. J Med Virol. 2023. PMID: 36056630 Free PMC article.
Peptidomimetic inhibitors of TMPRSS2 block SARS-CoV-2 infection in cell culture.
Wettstein L, Knaff PM, Kersten C, Müller P, Weil T, Conzelmann C, Müller JA, Brückner M, Hoffmann M, Pöhlmann S, Schirmeister T, Landfester K, Münch J, Mailänder V. Wettstein L, et al. Among authors: weil t. Commun Biol. 2022 Jul 8;5(1):681. doi: 10.1038/s42003-022-03613-4. Commun Biol. 2022. PMID: 35804152 Free PMC article.
Macromolecular Viral Entry Inhibitors as Broad-Spectrum First-Line Antivirals with Activity against SARS-CoV-2.
Groß R, Dias Loiola LM, Issmail L, Uhlig N, Eberlein V, Conzelmann C, Olari LR, Rauch L, Lawrenz J, Weil T, Müller JA, Cardoso MB, Gilg A, Larsson O, Höglund U, Pålsson SA, Tvilum AS, Løvschall KB, Kristensen MM, Spetz AL, Hontonnou F, Galloux M, Grunwald T, Zelikin AN, Münch J. Groß R, et al. Among authors: weil t. Adv Sci (Weinh). 2022 Jul;9(20):e2201378. doi: 10.1002/advs.202201378. Epub 2022 May 11. Adv Sci (Weinh). 2022. PMID: 35543527 Free PMC article.
Alpha-1 antitrypsin inhibits TMPRSS2 protease activity and SARS-CoV-2 infection.
Wettstein L, Weil T, Conzelmann C, Müller JA, Groß R, Hirschenberger M, Seidel A, Klute S, Zech F, Prelli Bozzo C, Preising N, Fois G, Lochbaum R, Knaff PM, Mailänder V, Ständker L, Thal DR, Schumann C, Stenger S, Kleger A, Lochnit G, Mayer B, Ruiz-Blanco YB, Hoffmann M, Sparrer KMJ, Pöhlmann S, Sanchez-Garcia E, Kirchhoff F, Frick M, Münch J. Wettstein L, et al. Among authors: weil t. Nat Commun. 2021 Mar 19;12(1):1726. doi: 10.1038/s41467-021-21972-0. Nat Commun. 2021. PMID: 33741941 Free PMC article.
Advanced Molecular Tweezers with Lipid Anchors against SARS-CoV-2 and Other Respiratory Viruses.
Weil T, Kirupakaran A, Le MH, Rebmann P, Mieres-Perez J, Issmail L, Conzelmann C, Müller JA, Rauch L, Gilg A, Wettstein L, Groß R, Read C, Bergner T, Pålsson SA, Uhlig N, Eberlein V, Wöll H, Klärner FG, Stenger S, Kümmerer BM, Streeck H, Fois G, Frick M, Braubach P, Spetz AL, Grunwald T, Shorter J, Sanchez-Garcia E, Schrader T, Münch J. Weil T, et al. JACS Au. 2022 Sep 6;2(9):2187-2202. doi: 10.1021/jacsau.2c00220. eCollection 2022 Sep 26. JACS Au. 2022. PMID: 36186568 Free PMC article.
Supramolecular Mechanism of Viral Envelope Disruption by Molecular Tweezers.
Weil T, Groß R, Röcker A, Bravo-Rodriguez K, Heid C, Sowislok A, Le MH, Erwin N, Dwivedi M, Bart SM, Bates P, Wettstein L, Müller JA, Harms M, Sparrer K, Ruiz-Blanco YB, Stürzel CM, von Einem J, Lippold S, Read C, Walther P, Hebel M, Kreppel F, Klärner FG, Bitan G, Ehrmann M, Weil T, Winter R, Schrader T, Shorter J, Sanchez-Garcia E, Münch J. Weil T, et al. J Am Chem Soc. 2020 Oct 7;142(40):17024-17038. doi: 10.1021/jacs.0c06400. Epub 2020 Sep 28. J Am Chem Soc. 2020. PMID: 32926779 Free PMC article.
22 results