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Year Number of Results
2012 1
2013 1
2014 2
2015 1
2016 2
2017 1
2018 2
2020 2
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10 results
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Page 1
One-Vector System for Multiplexed CRISPR/Cas9 against Hepatitis B Virus cccDNA Utilizing High-Capacity Adenoviral Vectors.
Schiwon M, Ehrke-Schulz E, Oswald A, Bergmann T, Michler T, Protzer U, Ehrhardt A. Schiwon M, et al. Among authors: michler t. Mol Ther Nucleic Acids. 2018 Sep 7;12:242-253. doi: 10.1016/j.omtn.2018.05.006. Epub 2018 Jun 7. Mol Ther Nucleic Acids. 2018. PMID: 30195763 Free PMC article.
Interferon-γ and Tumor Necrosis Factor-α Produced by T Cells Reduce the HBV Persistence Form, cccDNA, Without Cytolysis.
Xia Y, Stadler D, Lucifora J, Reisinger F, Webb D, Hösel M, Michler T, Wisskirchen K, Cheng X, Zhang K, Chou WM, Wettengel JM, Malo A, Bohne F, Hoffmann D, Eyer F, Thimme R, Falk CS, Thasler WE, Heikenwalder M, Protzer U. Xia Y, et al. Among authors: michler t. Gastroenterology. 2016 Jan;150(1):194-205. doi: 10.1053/j.gastro.2015.09.026. Epub 2015 Sep 28. Gastroenterology. 2016. PMID: 26416327
Data, reagents, assays and merits of proteomics for SARS-CoV-2 research and testing.
Zecha J, Lee CY, Bayer FP, Meng C, Grass V, Zerweck J, Schnatbaum K, Michler T, Pichlmair A, Ludwig C, Kuster B. Zecha J, et al. Among authors: michler t. Mol Cell Proteomics. 2020 Jun 26:mcp.RA120.002164. doi: 10.1074/mcp.RA120.002164. Online ahead of print. Mol Cell Proteomics. 2020. PMID: 32591346 Free article.
Novel viral and host targets to cure hepatitis B.
Ko C, Michler T, Protzer U. Ko C, et al. Among authors: michler t. Curr Opin Virol. 2017 Jun;24:38-45. doi: 10.1016/j.coviro.2017.03.019. Epub 2017 Apr 20. Curr Opin Virol. 2017. PMID: 28433762 Review.
New pharmacological strategies to fight enveloped viruses.
Wisskirchen K, Lucifora J, Michler T, Protzer U. Wisskirchen K, et al. Among authors: michler t. Trends Pharmacol Sci. 2014 Sep;35(9):470-8. doi: 10.1016/ Epub 2014 Aug 6. Trends Pharmacol Sci. 2014. PMID: 25108320 Free PMC article. Review.
Knockdown of Virus Antigen Expression Increases Therapeutic Vaccine Efficacy in High-Titer Hepatitis B Virus Carrier Mice.
Michler T, Kosinska AD, Festag J, Bunse T, Su J, Ringelhan M, Imhof H, Grimm D, Steiger K, Mogler C, Heikenwalder M, Michel ML, Guzman CA, Milstein S, Sepp-Lorenzino L, Knolle P, Protzer U. Michler T, et al. Gastroenterology. 2020 May;158(6):1762-1775.e9. doi: 10.1053/j.gastro.2020.01.032. Epub 2020 Jan 28. Gastroenterology. 2020. PMID: 32001321
Blocking sense-strand activity improves potency, safety and specificity of anti-hepatitis B virus short hairpin RNA.
Michler T, Große S, Mockenhaupt S, Röder N, Stückler F, Knapp B, Ko C, Heikenwalder M, Protzer U, Grimm D. Michler T, et al. EMBO Mol Med. 2016 Sep 1;8(9):1082-98. doi: 10.15252/emmm.201506172. Print 2016 Sep. EMBO Mol Med. 2016. PMID: 27473329 Free PMC article.
Hepatitis B virus infection enhances susceptibility toward adeno-associated viral vector transduction in vitro and in vivo.
Hösel M, Lucifora J, Michler T, Holz G, Gruffaz M, Stahnke S, Zoulim F, Durantel D, Heikenwalder M, Nierhoff D, Millet R, Salvetti A, Protzer U, Büning H. Hösel M, et al. Among authors: michler t. Hepatology. 2014 Jun;59(6):2110-20. doi: 10.1002/hep.26990. Epub 2014 Apr 30. Hepatology. 2014. PMID: 24425003
Activation of cannabinoid receptor 2 reduces inflammation in acute experimental pancreatitis via intra-acinar activation of p38 and MK2-dependent mechanisms.
Michler T, Storr M, Kramer J, Ochs S, Malo A, Reu S, Göke B, Schäfer C. Michler T, et al. Am J Physiol Gastrointest Liver Physiol. 2013 Jan 15;304(2):G181-92. doi: 10.1152/ajpgi.00133.2012. Epub 2012 Nov 8. Am J Physiol Gastrointest Liver Physiol. 2013. PMID: 23139224 Free article.