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Showing results for woosuk ko
Search for Wonsuk Ko instead (1 results)
RIG-I Deficiency Promotes Obesity-Induced Insulin Resistance.
Yang G, Lee HE, Seok JK, Kang HC, Cho YY, Lee HS, Lee JY. Yang G, et al. Pharmaceuticals (Basel). 2021 Nov 17;14(11):1178. doi: 10.3390/ph14111178. Pharmaceuticals (Basel). 2021. PMID: 34832960 Free PMC article.
In this study, we investigated whether RIG-I (retinoic acid-inducible gene I)-like receptors were involved in the regulation of obesity-induced metabolic stress in RIG-I knockout (KO) mice fed a high-fat diet (HFD). RIG-I KO mice fed an HFD for 12 weeks showed great …
In this study, we investigated whether RIG-I (retinoic acid-inducible gene I)-like receptors were involved in the regulation of obesity-indu …
Myeloid cell-specific sirtuin 6 deficiency delays wound healing in mice by modulating inflammation and macrophage phenotypes.
Koo JH, Jang HY, Lee Y, Moon YJ, Bae EJ, Yun SK, Park BH. Koo JH, et al. Exp Mol Med. 2019 Apr 26;51(4):1-10. doi: 10.1038/s12276-019-0248-9. Exp Mol Med. 2019. PMID: 31028245 Free PMC article.
To address this question, a full-thickness excisional lesion was made in the dorsal skin of myeloid cell-specific Sirt6 knockout (KO) and wild-type mice. Wound closure was delayed in the KO mice, which exhibited less collagen deposition, suppressed angiogenesis, and …
To address this question, a full-thickness excisional lesion was made in the dorsal skin of myeloid cell-specific Sirt6 knockout (KO) …
Hepatocyte-specific sirtuin 6 deletion predisposes to nonalcoholic steatohepatitis by up-regulation of Bach1, an Nrf2 repressor.
Ka SO, Bang IH, Bae EJ, Park BH. Ka SO, et al. FASEB J. 2017 Sep;31(9):3999-4010. doi: 10.1096/fj.201700098RR. Epub 2017 May 23. FASEB J. 2017. PMID: 28536120
HFHF-fed KO mice had increased hepatic steatosis and inflammation and aggravated glucose intolerance and insulin resistance compared with wild-type mice. HFHF-induced liver fibrosis and oxidative stress and related gene expression were significantly elevated in KO m …
HFHF-fed KO mice had increased hepatic steatosis and inflammation and aggravated glucose intolerance and insulin resistance compared …
GPR41 and GPR43: From development to metabolic regulation.
Lee DH, Kim MT, Han JH. Lee DH, et al. Biomed Pharmacother. 2024 May 13;175:116735. doi: 10.1016/j.biopha.2024.116735. Online ahead of print. Biomed Pharmacother. 2024. PMID: 38744220 Review.
However, despite intensive research using various strategies, including gene knockout (KO) mouse models, evidence about the precise roles of GPR41 and GPR43 in disease treatment remains inconsistent. ...
However, despite intensive research using various strategies, including gene knockout (KO) mouse models, evidence about the precise r …
36 results