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Prothrombotic activity of cytokine-activated endothelial cells and shear-activated platelets in the setting of ventricular assist device support.
Apostoli A, Bianchi V, Bono N, Dimasi A, Ammann KR, Moiia YR, Montisci A, Sheriff J, Bluestein D, Fiore GB, Pappalardo F, Candiani G, Redaelli A, Slepian MJ, Consolo F. Apostoli A, et al. Among authors: moiia yr. J Heart Lung Transplant. 2019 Jun;38(6):658-667. doi: 10.1016/j.healun.2019.02.009. Epub 2019 Feb 18. J Heart Lung Transplant. 2019. PMID: 30846234 Free PMC article.
Shear-mediated platelet activation in the free flow II: Evolving mechanobiological mechanisms reveal an identifiable signature of activation and a bi-directional platelet dyscrasia with thrombotic and bleeding features.
Roka-Moiia Y, Ammann KR, Miller-Gutierrez S, Sweedo A, Palomares D, Italiano J, Sheriff J, Bluestein D, Slepian MJ. Roka-Moiia Y, et al. J Biomech. 2021 Jun 23;123:110415. doi: 10.1016/j.jbiomech.2021.110415. Epub 2021 Apr 27. J Biomech. 2021. PMID: 34052772 Review.
Platelet Dysfunction During Mechanical Circulatory Support: Elevated Shear Stress Promotes Downregulation of αIIbβ3 and GPIb via Microparticle Shedding Decreasing Platelet Aggregability.
Roka-Moiia Y, Miller-Gutierrez S, Palomares DE, Italiano JE, Sheriff J, Bluestein D, Slepian MJ. Roka-Moiia Y, et al. Arterioscler Thromb Vasc Biol. 2021 Apr;41(4):1319-1336. doi: 10.1161/ATVBAHA.120.315583. Epub 2021 Feb 11. Arterioscler Thromb Vasc Biol. 2021. PMID: 33567867
11 results