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29 results

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Page 1
The evaluation of monoclonal gammopathy of renal significance: a consensus report of the International Kidney and Monoclonal Gammopathy Research Group.
Leung N, Bridoux F, Batuman V, Chaidos A, Cockwell P, D'Agati VD, Dispenzieri A, Fervenza FC, Fermand JP, Gibbs S, Gillmore JD, Herrera GA, Jaccard A, Jevremovic D, Kastritis E, Kukreti V, Kyle RA, Lachmann HJ, Larsen CP, Ludwig H, Markowitz GS, Merlini G, Mollee P, Picken MM, Rajkumar VS, Royal V, Sanders PW, Sethi S, Venner CP, Voorhees PM, Wechalekar AD, Weiss BM, Nasr SH. Leung N, et al. Nat Rev Nephrol. 2019 Jan;15(1):45-59. doi: 10.1038/s41581-018-0077-4. Nat Rev Nephrol. 2019. PMID: 30510265 Free PMC article.
The diagnosis of MGRS-related disease is established by kidney biopsy and immunofluorescence studies to identify the monotypic immunoglobulin deposits (although these deposits are minimal in patients with either C3 glomerulopathy or thrombotic microangiopathy). Accordingly …
The diagnosis of MGRS-related disease is established by kidney biopsy and immunofluorescence studies to identify the monotypic immunoglobuli …
Diagnosis of monoclonal gammopathy of renal significance.
Bridoux F, Leung N, Hutchison CA, Touchard G, Sethi S, Fermand JP, Picken MM, Herrera GA, Kastritis E, Merlini G, Roussel M, Fervenza FC, Dispenzieri A, Kyle RA, Nasr SH; International Kidney and Monoclonal Gammopathy Research Group. Bridoux F, et al. Kidney Int. 2015 Apr;87(4):698-711. doi: 10.1038/ki.2014.408. Epub 2015 Jan 21. Kidney Int. 2015. PMID: 25607108 Free article. Review.
The spectrum of renal diseases in MGRS is wide, including old entities such as AL amyloidosis and newly described lesions, particularly proliferative glomerulonephritis with monoclonal Ig deposits and C3 glomerulopathy with monoclonal gammopathy. Kidney biopsy is indicated …
The spectrum of renal diseases in MGRS is wide, including old entities such as AL amyloidosis and newly described lesions, particularly prol …
Neuroanatomy, Superior Cervical Ganglion.
Maningat AL, Munakomi S. Maningat AL, et al. 2023 Mar 30. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. 2023 Mar 30. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. PMID: 31335051 Free Books & Documents.
The superior cervical ganglia are approximately at the levels of the second cervical vertebra (C2) and the third cervical vertebra (C3), bilaterally. They typically lie lateral to the longus colli muscles, bilaterally. ...
The superior cervical ganglia are approximately at the levels of the second cervical vertebra (C2) and the third cervical vertebra (C3 …
COVID-19: A collision of complement, coagulation and inflammatory pathways.
Chauhan AJ, Wiffen LJ, Brown TP. Chauhan AJ, et al. J Thromb Haemost. 2020 Sep;18(9):2110-2117. doi: 10.1111/jth.14981. Epub 2020 Aug 27. J Thromb Haemost. 2020. PMID: 32608159 Free PMC article. Review.
Parallels with systemic inflammatory disorders such as atypical hemolytic uremic syndrome (aHUS) have implicated the complement pathway in the pathogenesis of COVID-19, and particularly the anaphylatoxins C3a and C5a released from cleavage of C3 and C5, respectively. C5a i …
Parallels with systemic inflammatory disorders such as atypical hemolytic uremic syndrome (aHUS) have implicated the complement pathway in t …
Loin pain haematuria syndrome.
Burke JR, Hardie IR. Burke JR, et al. Pediatr Nephrol. 1996 Apr;10(2):216-20. doi: 10.1007/BF00862087. Pediatr Nephrol. 1996. PMID: 8703718 Review.
Renal histology may show minor abnormalities, including mesangial proliferation, arteriolar and arterial hyalinosis and C3 in arterioles. Renal angiography is often normal but changes in intrarenal arterioles and cortical infarcts may be seen. ...
Renal histology may show minor abnormalities, including mesangial proliferation, arteriolar and arterial hyalinosis and C3 in arterio …
Hypertension: An immune related disorder?
Sereti E, Stamatelopoulos KS, Zakopoulos NA, Evangelopoulou A, Mavragani CP, Evangelopoulos ME. Sereti E, et al. Clin Immunol. 2020 Mar;212:108247. doi: 10.1016/j.clim.2019.108247. Epub 2019 Aug 8. Clin Immunol. 2020. PMID: 31401215
A full immunological profile including quantification of immunoglobulins (IgG, IgM, IgA) and lymphocyte subpopulations was also obtained. Immunoglobulin levels IgG, IgA and IgM and complement factor C3 were found to be significantly increased in the hypertensive compared t …
A full immunological profile including quantification of immunoglobulins (IgG, IgM, IgA) and lymphocyte subpopulations was also obtained. Im …
IgG4-related autoimmune manifestations in Alemtuzumab-treated multiple sclerosis patients.
Vakrakou AG, Tzanetakos D, Evangelopoulos ME, Fragoulis GE, Kazakou P, Lekka E, Kafasi N, Tzartos JS, Andreadou E, Koutsis G, Gialafos E, Dimitrakopoulos A, Zampeli E, Rontogianni D, Theocharis S, Zapanti E, Stathopoulos PA, Anagnostouli M, Stefanis L, Kilidireas C. Vakrakou AG, et al. J Neuroimmunol. 2021 Dec 15;361:577759. doi: 10.1016/j.jneuroim.2021.577759. Epub 2021 Oct 29. J Neuroimmunol. 2021. PMID: 34742035
Compared to baseline, total IgG-levels showed a trend towards reduced levels following two-courses of Alemtuzumab, but no significant change of C3 and/or C4-levels was observed. In conclusion, monitoring of IgG4-levels can serve as a marker for secondary autoimmunity risk …
Compared to baseline, total IgG-levels showed a trend towards reduced levels following two-courses of Alemtuzumab, but no significant change …
Additive contribution of microRNA-34a/b/c to human arterial ageing and atherosclerosis.
Gatsiou A, Georgiopoulos G, Vlachogiannis NI, Pfisterer L, Fischer A, Sachse M, Laina A, Bonini F, Delialis D, Tual-Chalot S, Zormpas E, Achangwa R, Jiang L, Kontogiannis C, Patras R, Hermeking H, Zeiher AM, Stamatelopoulos K, Dimmeler S, Stellos K. Gatsiou A, et al. Atherosclerosis. 2021 Jun;327:49-58. doi: 10.1016/j.atherosclerosis.2021.05.005. Epub 2021 May 15. Atherosclerosis. 2021. PMID: 34038763
Relation of total sugars, fructose and sucrose with incident type 2 diabetes: a systematic review and meta-analysis of prospective cohort studies.
Tsilas CS, de Souza RJ, Mejia SB, Mirrahimi A, Cozma AI, Jayalath VH, Ha V, Tawfik R, Di Buono M, Jenkins AL, Leiter LA, Wolever TMS, Beyene J, Khan T, Kendall CWC, Jenkins DJA, Sievenpiper JL. Tsilas CS, et al. CMAJ. 2017 May 23;189(20):E711-E720. doi: 10.1503/cmaj.160706. CMAJ. 2017. PMID: 28536126 Free PMC article. Review.
29 results