Risedronate increases osteoblastic differentiation and function through connexin43.
Jeong HM, Jin YH, Choi YH, Chung JO, Cho DH, Chung MY, Civitelli R, Chung DJ, Lee KY.
Jeong HM, et al.
Biochem Biophys Res Commun. 2013 Mar 1;432(1):152-6. doi: 10.1016/j.bbrc.2013.01.068. Epub 2013 Jan 29.
Biochem Biophys Res Commun. 2013.
PMID: 23376077
In addition to inhibiting osteoclast function, bisphosphonates have been reported to also promote survival of osteocyte and osteoblast via an anti-apoptotic effect, mediated by opening of hemi-gap junction channels formed by connexin43 (Cx43). In this study, we investigate …
In addition to inhibiting osteoclast function, bisphosphonates have been reported to also promote survival of osteocyte and osteoblast via a …