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Chaihu-Shugan-San inhibits neuroinflammation in the treatment of post-stroke depression through the JAK/STAT3-GSK3beta/PTEN/Akt pathway.
Fan Q, Liu Y, Sheng L, Lv S, Yang L, Zhang Z, Guo J, Fan Y, Hu D. Fan Q, et al. Biomed Pharmacother. 2023 Apr;160:114385. doi: 10.1016/j.biopha.2023.114385. Epub 2023 Feb 10. Biomed Pharmacother. 2023. PMID: 36774722 Free article.
The rats were then allocated to experimental groups (n = 15) that were treated with Chaihu-Shugan-San, a JAK-STAT3 inhibitor, a GSK3beta overexpressing virus, or an empty virus (control). ...Flow cytometry showed microglia polarization towards the M1 phenotype in an in vit …
The rats were then allocated to experimental groups (n = 15) that were treated with Chaihu-Shugan-San, a JAK-STAT3 inhibitor, a GSK3b …
Shugan granule contributes to the improvement of depression-like behaviors in chronic restraint stress-stimulated rats by altering gut microbiota.
Li J, Li Y, Duan W, Zhao Z, Yang L, Wei W, Li J, Li Y, Yu Y, Dai B, Guo R. Li J, et al. CNS Neurosci Ther. 2022 Sep;28(9):1409-1424. doi: 10.1111/cns.13881. Epub 2022 Jun 17. CNS Neurosci Ther. 2022. PMID: 35713215 Free PMC article.
AIM: The investigation aims to evaluate the potential effect of Shugan Granule (SGKL) on the gut, brain, and behaviors in rats exposed to chronic restraint stress (CRS). ...
AIM: The investigation aims to evaluate the potential effect of Shugan Granule (SGKL) on the gut, brain, and behaviors in rats expose …
Intervention of Shugan Xiaozhi Decoction on Nonalcoholic Fatty Liver Disease via Mediating Gut-Liver Axis.
Yang H, Feng L, Xu L, Jiang D, Zhai F, Tong G, Xing Y. Yang H, et al. Biomed Res Int. 2022 Jul 5;2022:4801695. doi: 10.1155/2022/4801695. eCollection 2022. Biomed Res Int. 2022. PMID: 35837380 Free PMC article.
Nonalcoholic fatty liver disease (NAFLD) is a chronic liver disease with an increasing incidence rate but few therapies. Shugan Xiaozhi decoction (SX) has demonstrated beneficial effects in treating NAFLD with an unclear mechanism. ...
Nonalcoholic fatty liver disease (NAFLD) is a chronic liver disease with an increasing incidence rate but few therapies. Shugan Xiaoz …
Mechanisms of paeoniaceae action as an antidepressant.
Guo W, Yao X, Cui R, Yang W, Wang L. Guo W, et al. Front Pharmacol. 2023 Feb 8;13:934199. doi: 10.3389/fphar.2022.934199. eCollection 2022. Front Pharmacol. 2023. PMID: 36844911 Free PMC article. Review.
Paeoniflorin (PF) has been widely used for the treatment of depression in mice models, some Chinese herbal compound containing PF on treating depression, such as Xiaoyao San, Chaihu-Shugan-San, Danggui Shaoyao San etc. Many experiments are also verifying whether PF in thes …
Paeoniflorin (PF) has been widely used for the treatment of depression in mice models, some Chinese herbal compound containing PF on treatin …
Proteomics Study Reveals the Anti-Depressive Mechanisms and the Compatibility Advantage of Chaihu-Shugan-San in a Rat Model of Chronic Unpredictable Mild Stress.
Zhu X, Li T, Hu E, Duan L, Zhang C, Wang Y, Tang T, Yang Z, Fan R. Zhu X, et al. Front Pharmacol. 2022 Jan 17;12:791097. doi: 10.3389/fphar.2021.791097. eCollection 2021. Front Pharmacol. 2022. PMID: 35111057 Free PMC article.
Compared with Shu Gan and Rou Gan, the 22 Chaihu-Shugan-San advanced proteins and the affected GABA pathway may be the advantages of Chaihu-Shugan-San compatibility. This research offers data and theory support for the clinical application of Chaihu-Shugan-Sa …
Compared with Shu Gan and Rou Gan, the 22 Chaihu-Shugan-San advanced proteins and the affected GABA pathway may be the advantages of …
Exploring mechanisms of Chaihu-Shugan-San against liver fibrosis by integrated multi-omics and network pharmacology approach.
Xie Z, Xie Z, Trujillo NP, Yang T, Yang C. Xie Z, et al. Biosci Rep. 2022 Jul 29;42(7):BSR20221030. doi: 10.1042/BSR20221030. Biosci Rep. 2022. PMID: 35791909 Free PMC article.
Chaihu-Shugan-San (CHSGS), a noted traditional Chinese medicine formula, has been used as a complementary and alternative therapy for liver fibrosis. ...
Chaihu-Shugan-San (CHSGS), a noted traditional Chinese medicine formula, has been used as a complementary and alternative therapy for …
Chaihu Shugan powder influences nonalcoholic fatty liver disease in rats in remodeling microRNAome and decreasing fatty acid synthesis.
Zheng C, Nie H, Pan M, Fan W, Pi D, Liang Z, Liu D, Wang F, Yang Q, Zhang Y. Zheng C, et al. J Ethnopharmacol. 2024 Jan 10;318(Pt A):116967. doi: 10.1016/j.jep.2023.116967. Epub 2023 Jul 26. J Ethnopharmacol. 2024. PMID: 37506783
ETHNOPHARMACOLOGICAL RELEVANCE: Chaihu Shugan powder (CSP) plays an important role in the prevention and treatment of nonalcoholic fatty liver disease (NAFLD) through a variety of biological mechanisms. ...
ETHNOPHARMACOLOGICAL RELEVANCE: Chaihu Shugan powder (CSP) plays an important role in the prevention and treatment of nonalcoholic fa …
Effect of Chaihu-Shugan-San on functional dyspepsia and gut microbiota: A randomized, double-blind, placebo-controlled trial.
Wang Y, Jia Y, Liu X, Yang K, Lin Y, Shao Q, Ling J. Wang Y, et al. J Ethnopharmacol. 2024 Mar 25;322:117659. doi: 10.1016/j.jep.2023.117659. Epub 2023 Dec 25. J Ethnopharmacol. 2024. PMID: 38151181 Free article. Clinical Trial.
ETHNOPHARMACOLOGICAL RELEVANCE: Chaihu-Shugan-San (CSS) is a classic traditional Chinese medicine (TCM) formula from the Ming Dynasty "Jingyue's Complete Works". ...AIM OF THE STUDY: To evaluate the therapeutic efficacy of Chaihu-Shugan-San (CSS) for treating functi …
ETHNOPHARMACOLOGICAL RELEVANCE: Chaihu-Shugan-San (CSS) is a classic traditional Chinese medicine (TCM) formula from the Ming Dynasty …
Modified chaihu shugan powder for functional dyspepsia: meta-analysis for randomized controlled trial.
Yang N, Jiang X, Qiu X, Hu Z, Wang L, Song M. Yang N, et al. Evid Based Complement Alternat Med. 2013;2013:791724. doi: 10.1155/2013/791724. Epub 2013 May 13. Evid Based Complement Alternat Med. 2013. PMID: 23762161 Free PMC article.
Context. Modified Chaihu Shugan powder (MCSP) is a popular traditional Chinese herbal formula for functional dyspepsia, which is revised from Chaihu Shugan San and recorded in a medical classic works of China. ...Twenty-two clinical trials involving 1998 participant …
Context. Modified Chaihu Shugan powder (MCSP) is a popular traditional Chinese herbal formula for functional dyspepsia, which is revi …
Notable efficacy of Shugan Jieyu capsule in treating adult with post-stroke depression: A PRISMA-compliant meta-analysis of randomized controlled trials.
Wu T, Yue T, Yang P, Jia Y. Wu T, et al. J Ethnopharmacol. 2022 Aug 10;294:115367. doi: 10.1016/j.jep.2022.115367. Epub 2022 May 10. J Ethnopharmacol. 2022. PMID: 35562090 Free article.
ETHNOPHARMACOLOGICAL RELEVANCE: Post stroke depression (PSD), which happens in 40%-60% stroke patients, is one of the most common complications after cerebrovascular accident. Shugan Jieyu Capsule (SGJYC), a traditional Chinese medicine, has been widely prescribed for PSD …
ETHNOPHARMACOLOGICAL RELEVANCE: Post stroke depression (PSD), which happens in 40%-60% stroke patients, is one of the most common complicati …
40 results