Similar articles for PMID: 10758162

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1

Human neutrophil immunodeficiency syndrome is associated with an inhibitory Rac2 mutation.

Ambruso DR, Knall C, Abell AN, Panepinto J, Kurkchubasche A, Thurman G, Gonzalez-Aller C, Hiester A, deBoer M, Harbeck RJ, Oyer R, Johnson GL, Roos D. Ambruso DR, et al. Proc Natl Acad Sci U S A. 2000 Apr 25;97(9):4654-9. doi: 10.1073/pnas.080074897. Proc Natl Acad Sci U S A. 2000. PMID: 10758162 Free PMC article.

2

Biochemical and biological characterization of a human Rac2 GTPase mutant associated with phagocytic immunodeficiency.

Gu Y, Jia B, Yang FC, D'Souza M, Harris CE, Derrow CW, Zheng Y, Williams DA. Gu Y, et al. J Biol Chem. 2001 May 11;276(19):15929-38. doi: 10.1074/jbc.M010445200. Epub 2001 Feb 22. J Biol Chem. 2001. PMID: 11278678 Free article.

3

Rac GTPase isoform-specific regulation of NADPH oxidase and chemotaxis in murine neutrophils in vivo. Role of the C-terminal polybasic domain.

Yamauchi A, Marchal CC, Molitoris J, Pech N, Knaus U, Towe J, Atkinson SJ, Dinauer MC. Yamauchi A, et al. J Biol Chem. 2005 Jan 14;280(2):953-64. doi: 10.1074/jbc.M408820200. Epub 2004 Oct 25. J Biol Chem. 2005. PMID: 15504745 Free article.

4

Dominant negative mutation of the hematopoietic-specific Rho GTPase, Rac2, is associated with a human phagocyte immunodeficiency.

Williams DA, Tao W, Yang F, Kim C, Gu Y, Mansfield P, Levine JE, Petryniak B, Derrow CW, Harris C, Jia B, Zheng Y, Ambruso DR, Lowe JB, Atkinson SJ, Dinauer MC, Boxer L. Williams DA, et al. Blood. 2000 Sep 1;96(5):1646-54. Blood. 2000. PMID: 10961859 Free article.

5

Rac2 concentrations in umbilical cord neutrophils.

Meade VM, Barese CN, Kim C, Njinimbam CG, Marchal CC, Ingram DA, Clapp DW, Dinauer MC, Yoder MC. Meade VM, et al. Biol Neonate. 2006;90(3):156-9. doi: 10.1159/000092451. Epub 2006 Mar 30. Biol Neonate. 2006. PMID: 16582540

6

Dominant activating RAC2 mutation with lymphopenia, immunodeficiency, and cytoskeletal defects.

Hsu AP, Donkó A, Arrington ME, Swamydas M, Fink D, Das A, Escobedo O, Bonagura V, Szabolcs P, Steinberg HN, Bergerson J, Skoskiewicz A, Makhija M, Davis J, Foruraghi L, Palmer C, Fuleihan RL, Church JA, Bhandoola A, Lionakis MS, Campbell S, Leto TL, Kuhns DB, Holland SM. Hsu AP, et al. Blood. 2019 May 2;133(18):1977-1988. doi: 10.1182/blood-2018-11-886028. Epub 2019 Feb 5. Blood. 2019. PMID: 30723080 Free PMC article.

7

RAC2 GTPase deficiency and myeloid cell dysfunction in human and mouse.

Gu Y, Williams DA. Gu Y, et al. J Pediatr Hematol Oncol. 2002 Dec;24(9):791-4. doi: 10.1097/00043426-200212000-00027. J Pediatr Hematol Oncol. 2002. PMID: 12468931 Review.

8

Clinical features of a human Rac2 mutation: a complex neutrophil dysfunction disease.

Kurkchubasche AG, Panepinto JA, Tracy TF Jr, Thurman GW, Ambruso DR. Kurkchubasche AG, et al. J Pediatr. 2001 Jul;139(1):141-7. doi: 10.1067/mpd.2001.114718. J Pediatr. 2001. PMID: 11445809

9

8-oxo-7,8-dihydroguanosine triphosphate(8-oxoGTP) down-regulates respiratory burst of neutrophils by antagonizing GTP toward Rac, a small GTP binding protein.

Kim HJ, Yoon SH, Ryu HO, Yoon BH, Choi S, Ye SK, Chung MH. Kim HJ, et al. Free Radic Res. 2007 Jun;41(6):655-62. doi: 10.1080/10715760701250270. Free Radic Res. 2007. PMID: 17516238

10

Localization of Rac2 via the C terminus and aspartic acid 150 specifies superoxide generation, actin polarity and chemotaxis in neutrophils.

Filippi MD, Harris CE, Meller J, Gu Y, Zheng Y, Williams DA. Filippi MD, et al. Nat Immunol. 2004 Jul;5(7):744-51. doi: 10.1038/ni1081. Epub 2004 May 30. Nat Immunol. 2004. PMID: 15170212

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