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14662709,16875977,15840038,12826020,16675725,18669935,19289643,17446439,19291087,20022989,15728785,16029909,15234404,9329964,9730857,18037769,12874192,17974492,9628275,15864218,12799312,12639216,15763942,19995356,17319111,10920304,12382080,10409468,17126666,10393040,15321699,11055001,12874186,19410250,11410114,9310114,21555712,14567772,15451794,10666424,9631871,16620305,11139472,15476630,15204243,15068405,17413035,15364625,17572144,21633396,10702649,10690343,11126415,18682435,11557915,12484504,8988069,9680496,7554193,12695418,17132537,23183942,17502494,15367100,17339540,16054252,16373196,12915662,17919260,15777779,10942160,14530204,15361763,10072715,9754590,16824074,17174609,16621868,12607129,8901748,15642763,19528518,10435049,16864730,11003752,16260640,15295720,12891196,16794224,11509489,10887058,20050880,15691863,16179595,18391107,10998481,12811255,15953770,16386809,16520350,16396667,22194324,8890810,16957554,16150654,8641023,12625832,11244022,9059312,10869260,10811592,12665482,7690095,15556052,22307673,28846879,18281379,12714434,18039979,11052918,11003746,11869173,12883448,9059313,26058441,16129443,10720962,12509498,9663809,9568345,11914243,11606734,22412088,12957683,11748103,10218735,12027232,23221860,11401935,11208686,20224425,14686876,11397846,10945318,21450569,11739299,11216830,10690892,11441201,21143196,25323945,34822809,16210569,11171280,9014982,12096067,17645881,11594733,26224075,24607773,11728357,12135314,12538427,11862115,16103236,12074278,21262998,10383544,12699800,10484540,21088673,9470056,9796306,10069678,9781924,12584225,18516617,16160030,15019545,12937030,28212823,10555898,7700060,11393673,10500040,10696525,11867622,16102774,11991214,8960576,8872666,12163881,19615687,10613099,12149108,21122149,10209003,11238095,24043253,21724735,12679222,8964118,11100391,12875761,1566022,20083732,12003853,9296326,11723017,11583890,10334805,10404842,20010901,8942395,34743333,1511805,1469103,10806013,17228074,9193429,12745514,9546960,8994420,8550838,8287660,10961964,9054840,10673249,11051805,11134122,11748093,12164090,11309554,8764252,11768732,11171787,27643673,26801312,11433834,12831815,10555897,9768710,9251746,14717337,10225462,11157665,25820391,12586744,7528302,3677333,11964373,20395940,15947284,11991218,12454227,12923398,9452776,26276790,9536920,11425490,10470994,12031713,11689204,12449445,10610742,26420355,21813128,28070018,20807789,11358157,11488770,20064642,20145417,10811593,12241530,11153725,10526899,11723010,20840194,23090775,30378151,10488962,12234948,17612649,9468210,10867445,10920068,10533619,12464247,15715683,11171786,8759065,9540231,9468080,14684755,9534865,11966784,19049846,9709409,26919997,11123219,22802226,9592708,16079640,10561804,20134098,22674719,24512733,12512703,14621053,11710783,26707366,22411759,10440166,12050273,10455522,18086957,11263609,18571252,11230288,8721436,12480559,19717402,10961963,29158357,12975258,11137850,18489612,11820226,16527283,9495273,10910444,10549401,11264550,26284284,12241543,10595615,14729785,16141426,21252221,11786526,12573493,34488434,15187819,9270179,8248689,12422891,15964928,12777324,23525432,29980050,24519941,22784510,10785676,11190286,11882600,15778282,24818316,32978862,30526321,10465239,27208415,11117366,20383717,11077122,30261342,25072937,12837129,17332665,16543269,10390117,9050817,11048470,26442881,18671702,12883329,28385576,12791593,11251063,11214429,12224822,1285964,15840008,10729391,8535551,11136508,10419439,11560189,15671911,12850828,16845886,9833607,24552391,7493433,21441311,11990728,7898251,2197313,8579516,10610734,12685963,10077440,8822966,18557730,18408337,10865852,36297480,19901200,35871073,13689675,8168329,36168589,1233073,881646,13992327,5826385,14203652,3240474,14198444,13980250,3799400,34252499,13655792,13622387,13622383[uid]

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Inhibition of cytochrome P450 2C9 improves endothelium-dependent, nitric oxide-mediated vasodilatation in patients with coronary artery disease.

Fichtlscherer S, Dimmeler S, Breuer S, Busse R, Zeiher AM, Fleming I. Fichtlscherer S, et al. Circulation. 2004 Jan 20;109(2):178-83. doi: 10.1161/01.CIR.0000105763.51286.7F. Epub 2003 Dec 8. Circulation. 2004. PMID: 14662709 Clinical Trial.

Identification of a cytochrome P450 2C9-derived endothelium-derived hyperpolarizing factor in essential hypertensive patients.

Taddei S, Versari D, Cipriano A, Ghiadoni L, Galetta F, Franzoni F, Magagna A, Virdis A, Salvetti A. Taddei S, et al. J Am Coll Cardiol. 2006 Aug 1;48(3):508-15. doi: 10.1016/j.jacc.2006.04.074. Epub 2006 Jul 12. J Am Coll Cardiol. 2006. PMID: 16875977 Free article.

Nitric oxide- and EDHF-mediated arteriolar tone in uremia is unaffected by selective inhibition of vascular cytochrome P450 2C9.

Passauer J, Pistrosch F, Lässig G, Herbrig K, Büssemaker E, Gross P, Fleming I. Passauer J, et al. Kidney Int. 2005 May;67(5):1907-12. doi: 10.1111/j.1523-1755.2005.00289.x. Kidney Int. 2005. PMID: 15840038 Free article.

Baseline blood flow and bradykinin-induced vasodilator responses in the human forearm are insensitive to the cytochrome P450 2C9 (CYP2C9) inhibitor sulphaphenazole.

Passauer J, Büssemaker E, Lässig G, Pistrosch F, Fauler J, Gross P, Fleming I. Passauer J, et al. Clin Sci (Lond). 2003 Oct;105(4):513-8. doi: 10.1042/CS20030118. Clin Sci (Lond). 2003. PMID: 12826020 Clinical Trial.

Clopidogrel improves systemic endothelial nitric oxide bioavailability in patients with coronary artery disease: evidence for antioxidant and antiinflammatory effects.

Heitzer T, Rudolph V, Schwedhelm E, Karstens M, Sydow K, Ortak M, Tschentscher P, Meinertz T, Böger R, Baldus S. Heitzer T, et al. Arterioscler Thromb Vasc Biol. 2006 Jul;26(7):1648-52. doi: 10.1161/01.ATV.0000225288.74170.dc. Epub 2006 May 4. Arterioscler Thromb Vasc Biol. 2006. PMID: 16675725 Clinical Trial.

Cytochrome P-450 2C9 signaling does not contribute to age-associated vascular endothelial dysfunction in humans.

Donato AJ, Eskurza I, Jablonski KL, Gano LB, Pierce GL, Seals DR. Donato AJ, et al. J Appl Physiol (1985). 2008 Oct;105(4):1359-63. doi: 10.1152/japplphysiol.90629.2008. Epub 2008 Jul 31. J Appl Physiol (1985). 2008. PMID: 18669935 Free PMC article.

Effect of sulfaphenazole on tissue plasminogen activator release in normotensive subjects and hypertensive patients.

Giannarelli C, Virdis A, De Negri F, Magagna A, Duranti E, Salvetti A, Taddei S. Giannarelli C, et al. Circulation. 2009 Mar 31;119(12):1625-33. doi: 10.1161/CIRCULATIONAHA.108.782482. Epub 2009 Mar 16. Circulation. 2009. PMID: 19289643

Repetition of ischemic preconditioning augments endothelium-dependent vasodilation in humans: role of endothelium-derived nitric oxide and endothelial progenitor cells.

Kimura M, Ueda K, Goto C, Jitsuiki D, Nishioka K, Umemura T, Noma K, Yoshizumi M, Chayama K, Higashi Y. Kimura M, et al. Arterioscler Thromb Vasc Biol. 2007 Jun;27(6):1403-10. doi: 10.1161/ATVBAHA.107.143578. Epub 2007 Apr 19. Arterioscler Thromb Vasc Biol. 2007. PMID: 17446439 Clinical Trial.

The role of nitric oxide- and prostacyclin-independent vasodilatation in the human cutaneous microcirculation: effect of cytochrome P450 2C9 inhibition.

Lenasi H. Lenasi H. Clin Physiol Funct Imaging. 2009 Jul;29(4):263-70. doi: 10.1111/j.1475-097X.2009.00862.x. Epub 2009 Mar 8. Clin Physiol Funct Imaging. 2009. PMID: 19291087

The sulfaphenazole-sensitive pathway acts as a compensatory mechanism for impaired nitric oxide availability in patients with primary hyperparathyroidism. Effect of surgical treatment.

Virdis A, Cetani F, Giannarelli C, Banti C, Ghiadoni L, Ambrogini E, Carrara D, Pinchera A, Taddei S, Bernini G, Marcocci C. Virdis A, et al. J Clin Endocrinol Metab. 2010 Feb;95(2):920-7. doi: 10.1210/jc.2009-1669. Epub 2009 Dec 18. J Clin Endocrinol Metab. 2010. PMID: 20022989

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