Similar articles for PMID: 21701785

Year	Number of Results
2003	2
2005	1
2006	4
2007	2
2008	11
2009	9
2010	2
2011	8
2012	11
2013	11
2014	14
2015	8
2016	10
2017	10
2018	3
2019	1
2020	5
2021	5
2022	3
2023	1
2024	0

1

Novel variant Pro143Ala in HTRA2 contributes to Parkinson's disease by inducing hyperphosphorylation of HTRA2 protein in mitochondria.

Lin CH, Chen ML, Chen GS, Tai CH, Wu RM. Lin CH, et al. Hum Genet. 2011 Dec;130(6):817-27. doi: 10.1007/s00439-011-1041-6. Epub 2011 Jun 24. Hum Genet. 2011. PMID: 21701785 Free PMC article.

2

HTRA2 variations in Taiwanese Parkinson's disease.

Chen CM, Wu CH, Hsieh CH, Lin CH, Chen IC, Chen YC, Lee LC, Lee CM, Tseng YC, Lee-Chen GJ, Wu YR. Chen CM, et al. J Neural Transm (Vienna). 2014 May;121(5):491-8. doi: 10.1007/s00702-013-1131-9. Epub 2013 Dec 12. J Neural Transm (Vienna). 2014. PMID: 24337630

3

Mitochondrial defects and neurodegeneration in mice overexpressing wild-type or G399S mutant HtrA2.

Casadei N, Sood P, Ulrich T, Fallier-Becker P, Kieper N, Helling S, May C, Glaab E, Chen J, Nuber S, Wolburg H, Marcus K, Rapaport D, Ott T, Riess O, Krüger R, Fitzgerald JC. Casadei N, et al. Hum Mol Genet. 2016 Feb 1;25(3):459-71. doi: 10.1093/hmg/ddv485. Epub 2015 Nov 24. Hum Mol Genet. 2016. PMID: 26604148

4

Loss of GSK-3β mediated phosphorylation in HtrA2 contributes to uncontrolled cell death with Parkinsonian phenotype.

Bose K, Wagh A, Mishra V, Dutta S, Parui AL, Puja R, Mudrale SP, Kulkarni SS, Gai PB, Sarin R. Bose K, et al. Int J Biol Macromol. 2021 Jun 1;180:97-111. doi: 10.1016/j.ijbiomac.2021.03.040. Epub 2021 Mar 12. Int J Biol Macromol. 2021. PMID: 33716130

5

A large-scale genetic association study to evaluate the contribution of Omi/HtrA2 (PARK13) to Parkinson's disease.

Krüger R, Sharma M, Riess O, Gasser T, Van Broeckhoven C, Theuns J, Aasly J, Annesi G, Bentivoglio AR, Brice A, Djarmati A, Elbaz A, Farrer M, Ferrarese C, Gibson JM, Hadjigeorgiou GM, Hattori N, Ioannidis JP, Jasinska-Myga B, Klein C, Lambert JC, Lesage S, Lin JJ, Lynch T, Mellick GD, de Nigris F, Opala G, Prigione A, Quattrone A, Ross OA, Satake W, Silburn PA, Tan EK, Toda T, Tomiyama H, Wirdefeldt K, Wszolek Z, Xiromerisiou G, Maraganore DM; Genetic Epidemiology of Parkinson's disease consortium. Krüger R, et al. Neurobiol Aging. 2011 Mar;32(3):548.e9-18. doi: 10.1016/j.neurobiolaging.2009.11.021. Epub 2009 Dec 24. Neurobiol Aging. 2011. PMID: 20036034 Free PMC article.

6

What have PINK1 and HtrA2 genes told us about the role of mitochondria in Parkinson's disease?

Plun-Favreau H, Gandhi S, Wood-Kaczmar A, Deas E, Yao Z, Wood NW. Plun-Favreau H, et al. Ann N Y Acad Sci. 2008 Dec;1147:30-6. doi: 10.1196/annals.1427.032. Ann N Y Acad Sci. 2008. PMID: 19076428

7

Sequencing analysis of OMI/HTRA2 shows previously reported pathogenic mutations in neurologically normal controls.

Simón-Sánchez J, Singleton AB. Simón-Sánchez J, et al. Hum Mol Genet. 2008 Jul 1;17(13):1988-93. doi: 10.1093/hmg/ddn096. Epub 2008 Mar 25. Hum Mol Genet. 2008. PMID: 18364387 Free PMC article.

8

Metformin reverses TRAP1 mutation-associated alterations in mitochondrial function in Parkinson's disease.

Fitzgerald JC, Zimprich A, Carvajal Berrio DA, Schindler KM, Maurer B, Schulte C, Bus C, Hauser AK, Kübler M, Lewin R, Bobbili DR, Schwarz LM, Vartholomaiou E, Brockmann K, Wüst R, Madlung J, Nordheim A, Riess O, Martins LM, Glaab E, May P, Schenke-Layland K, Picard D, Sharma M, Gasser T, Krüger R. Fitzgerald JC, et al. Brain. 2017 Sep 1;140(9):2444-2459. doi: 10.1093/brain/awx202. Brain. 2017. PMID: 29050400

9

Genetic variability in the mitochondrial serine protease HTRA2 contributes to risk for Parkinson disease.

Bogaerts V, Nuytemans K, Reumers J, Pals P, Engelborghs S, Pickut B, Corsmit E, Peeters K, Schymkowitz J, De Deyn PP, Cras P, Rousseau F, Theuns J, Van Broeckhoven C. Bogaerts V, et al. Hum Mutat. 2008 Jun;29(6):832-40. doi: 10.1002/humu.20713. Hum Mutat. 2008. PMID: 18401856

10

Genetic variations of Omi/HTRA2 in Chinese patients with Parkinson's disease.

Wang CY, Xu Q, Weng L, Zhang Q, Zhang HN, Guo JF, Tan LM, Tang JG, Yan XX, Tang BS. Wang CY, et al. Brain Res. 2011 Apr 18;1385:293-7. doi: 10.1016/j.brainres.2011.02.037. Epub 2011 Feb 19. Brain Res. 2011. PMID: 21338583

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