Similar articles for PMID: 23723238

Year	Number of Results
2008	3
2009	3
2010	4
2011	4
2012	8
2013	17
2014	12
2015	16
2016	12
2017	12
2018	14
2019	15
2020	13
2021	18
2022	29
2023	18
2024	0

1

A Tumor suppressor complex with GAP activity for the Rag GTPases that signal amino acid sufficiency to mTORC1.

Bar-Peled L, Chantranupong L, Cherniack AD, Chen WW, Ottina KA, Grabiner BC, Spear ED, Carter SL, Meyerson M, Sabatini DM. Bar-Peled L, et al. Science. 2013 May 31;340(6136):1100-6. doi: 10.1126/science.1232044. Science. 2013. PMID: 23723238 Free PMC article.

2

Arg-78 of Nprl2 catalyzes GATOR1-stimulated GTP hydrolysis by the Rag GTPases.

Shen K, Valenstein ML, Gu X, Sabatini DM. Shen K, et al. J Biol Chem. 2019 Feb 22;294(8):2970-2975. doi: 10.1074/jbc.AC119.007382. Epub 2019 Jan 16. J Biol Chem. 2019. PMID: 30651352 Free PMC article.

3

SZT2 dictates GATOR control of mTORC1 signalling.

Peng M, Yin N, Li MO. Peng M, et al. Nature. 2017 Mar 16;543(7645):433-437. doi: 10.1038/nature21378. Epub 2017 Feb 15. Nature. 2017. PMID: 28199315 Free PMC article.

4

Architecture of the human GATOR1 and GATOR1-Rag GTPases complexes.

Shen K, Huang RK, Brignole EJ, Condon KJ, Valenstein ML, Chantranupong L, Bomaliyamu A, Choe A, Hong C, Yu Z, Sabatini DM. Shen K, et al. Nature. 2018 Apr 5;556(7699):64-69. doi: 10.1038/nature26158. Epub 2018 Mar 28. Nature. 2018. PMID: 29590090 Free PMC article.

5

KICSTOR recruits GATOR1 to the lysosome and is necessary for nutrients to regulate mTORC1.

Wolfson RL, Chantranupong L, Wyant GA, Gu X, Orozco JM, Shen K, Condon KJ, Petri S, Kedir J, Scaria SM, Abu-Remaileh M, Frankel WN, Sabatini DM. Wolfson RL, et al. Nature. 2017 Mar 16;543(7645):438-442. doi: 10.1038/nature21423. Epub 2017 Feb 15. Nature. 2017. PMID: 28199306 Free PMC article.

6

Involvement of GATOR complex genes in familial focal epilepsies and focal cortical dysplasia.

Weckhuysen S, Marsan E, Lambrecq V, Marchal C, Morin-Brureau M, An-Gourfinkel I, Baulac M, Fohlen M, Kallay Zetchi C, Seeck M, de la Grange P, Dermaut B, Meurs A, Thomas P, Chassoux F, Leguern E, Picard F, Baulac S. Weckhuysen S, et al. Epilepsia. 2016 Jun;57(6):994-1003. doi: 10.1111/epi.13391. Epub 2016 May 13. Epilepsia. 2016. PMID: 27173016 Free article.

7

The folliculin tumor suppressor is a GAP for the RagC/D GTPases that signal amino acid levels to mTORC1.

Tsun ZY, Bar-Peled L, Chantranupong L, Zoncu R, Wang T, Kim C, Spooner E, Sabatini DM. Tsun ZY, et al. Mol Cell. 2013 Nov 21;52(4):495-505. doi: 10.1016/j.molcel.2013.09.016. Epub 2013 Oct 3. Mol Cell. 2013. PMID: 24095279 Free PMC article.

8

The Sestrins interact with GATOR2 to negatively regulate the amino-acid-sensing pathway upstream of mTORC1.

Chantranupong L, Wolfson RL, Orozco JM, Saxton RA, Scaria SM, Bar-Peled L, Spooner E, Isasa M, Gygi SP, Sabatini DM. Chantranupong L, et al. Cell Rep. 2014 Oct 9;9(1):1-8. doi: 10.1016/j.celrep.2014.09.014. Epub 2014 Sep 25. Cell Rep. 2014. PMID: 25263562 Free PMC article.

9

Amino acid-dependent NPRL2 interaction with Raptor determines mTOR Complex 1 activation.

Kwak SS, Kang KH, Kim S, Lee S, Lee JH, Kim JW, Byun B, Meadows GG, Joe CO. Kwak SS, et al. Cell Signal. 2016 Feb;28(2):32-41. doi: 10.1016/j.cellsig.2015.11.008. Epub 2015 Nov 12. Cell Signal. 2016. PMID: 26582740

10

Sestrins inhibit mTORC1 kinase activation through the GATOR complex.

Parmigiani A, Nourbakhsh A, Ding B, Wang W, Kim YC, Akopiants K, Guan KL, Karin M, Budanov AV. Parmigiani A, et al. Cell Rep. 2014 Nov 20;9(4):1281-91. doi: 10.1016/j.celrep.2014.10.019. Cell Rep. 2014. PMID: 25457612 Free PMC article.

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