Similar articles for PMID: 27783593

Year	Number of Results
2003	1
2004	4
2005	5
2007	3
2008	10
2009	10
2010	10
2011	9
2012	9
2013	16
2014	18
2015	10
2016	12
2017	13
2018	13
2019	18
2020	31
2021	18
2022	10
2023	5
2024	0

1

Leukaemogenic effects of Ptpn11 activating mutations in the stem cell microenvironment.

Dong L, Yu WM, Zheng H, Loh ML, Bunting ST, Pauly M, Huang G, Zhou M, Broxmeyer HE, Scadden DT, Qu CK. Dong L, et al. Nature. 2016 Nov 10;539(7628):304-308. doi: 10.1038/nature20131. Epub 2016 Oct 26. Nature. 2016. PMID: 27783593 Free PMC article.

2

Inflammatory response in hematopoietic stem and progenitor cells triggered by activating SHP2 mutations evokes blood defects.

Solman M, Blokzijl-Franke S, Piques F, Yan C, Yang Q, Strullu M, Kamel SM, Ak P, Bakkers J, Langenau DM, Cavé H, den Hertog J. Solman M, et al. Elife. 2022 May 10;11:e73040. doi: 10.7554/eLife.73040. Elife. 2022. PMID: 35535491 Free PMC article.

3

CCL3 is a key mediator for the leukemogenic effect of Ptpn11-activating mutations in the stem-cell microenvironment.

Dong L, Zheng H, Qu CK. Dong L, et al. Blood. 2017 Sep 21;130(12):1471-1474. doi: 10.1182/blood-2017-06-791103. Epub 2017 Jul 27. Blood. 2017. PMID: 28751523 Free PMC article. No abstract available.

4

Essential role of PTPN11 mutation in enhanced haematopoietic differentiation potential of induced pluripotent stem cells of juvenile myelomonocytic leukaemia.

Shigemura T, Matsuda K, Kurata T, Sakashita K, Okuno Y, Muramatsu H, Yue F, Ebihara Y, Tsuji K, Sasaki K, Nakahata T, Nakazawa Y, Koike K. Shigemura T, et al. Br J Haematol. 2019 Oct;187(2):163-173. doi: 10.1111/bjh.16060. Epub 2019 Jun 20. Br J Haematol. 2019. PMID: 31222725 Free article.

5

Non-lineage/stage-restricted effects of a gain-of-function mutation in tyrosine phosphatase Ptpn11 (Shp2) on malignant transformation of hematopoietic cells.

Xu D, Liu X, Yu WM, Meyerson HJ, Guo C, Gerson SL, Qu CK. Xu D, et al. J Exp Med. 2011 Sep 26;208(10):1977-88. doi: 10.1084/jem.20110450. Epub 2011 Sep 19. J Exp Med. 2011. PMID: 21930766 Free PMC article.

6

Myeloid Dysregulation in a Human Induced Pluripotent Stem Cell Model of PTPN11-Associated Juvenile Myelomonocytic Leukemia.

Mulero-Navarro S, Sevilla A, Roman AC, Lee DF, D'Souza SL, Pardo S, Riess I, Su J, Cohen N, Schaniel C, Rodriguez NA, Baccarini A, Brown BD, Cavé H, Caye A, Strullu M, Yalcin S, Park CY, Dhandapany PS, Yongchao G, Edelmann L, Bahieg S, Raynal P, Flex E, Tartaglia M, Moore KA, Lemischka IR, Gelb BD. Mulero-Navarro S, et al. Cell Rep. 2015 Oct 20;13(3):504-515. doi: 10.1016/j.celrep.2015.09.019. Epub 2015 Oct 8. Cell Rep. 2015. PMID: 26456833 Free PMC article.

7

Negative regulation of Stat3 by activating PTPN11 mutants contributes to the pathogenesis of Noonan syndrome and juvenile myelomonocytic leukemia.

Zhang W, Chan RJ, Chen H, Yang Z, He Y, Zhang X, Luo Y, Yin F, Moh A, Miller LC, Payne RM, Zhang ZY, Fu XY, Shou W. Zhang W, et al. J Biol Chem. 2009 Aug 14;284(33):22353-22363. doi: 10.1074/jbc.M109.020495. Epub 2009 Jun 9. J Biol Chem. 2009. PMID: 19509418 Free PMC article.

8

Functional evaluation of circulating hematopoietic progenitors in Noonan syndrome.

Timeus F, Crescenzio N, Baldassarre G, Doria A, Vallero S, Foglia L, Pagliano S, Rossi C, Silengo MC, Ramenghi U, Fagioli F, Cordero di Montezemolo L, Ferrero GB. Timeus F, et al. Oncol Rep. 2013 Aug;30(2):553-9. doi: 10.3892/or.2013.2535. Epub 2013 Jun 11. Oncol Rep. 2013. PMID: 23756559 Free PMC article.

9

A germline gain-of-function mutation in Ptpn11 (Shp-2) phosphatase induces myeloproliferative disease by aberrant activation of hematopoietic stem cells.

Xu D, Wang S, Yu WM, Chan G, Araki T, Bunting KD, Neel BG, Qu CK. Xu D, et al. Blood. 2010 Nov 4;116(18):3611-21. doi: 10.1182/blood-2010-01-265652. Epub 2010 Jul 22. Blood. 2010. PMID: 20651068 Free PMC article.

10

Yolk sac erythromyeloid progenitors expressing gain of function PTPN11 have functional features of JMML but are not sufficient to cause disease in mice.

Tarnawsky SP, Yoshimoto M, Deng L, Chan RJ, Yoder MC. Tarnawsky SP, et al. Dev Dyn. 2017 Dec;246(12):1001-1014. doi: 10.1002/dvdy.24598. Epub 2017 Oct 23. Dev Dyn. 2017. PMID: 28975680 Free PMC article.

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