Similar articles for PMID: 15829966

Year	Number of Results
2003	1
2004	3
2005	6
2006	4
2007	1
2008	5
2009	4
2010	9
2011	7
2012	11
2013	5
2014	3
2015	9
2016	11
2017	12
2018	6
2019	5
2020	9
2021	11
2022	18
2023	6
2024	0

1

Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase.

Bryant HE, Schultz N, Thomas HD, Parker KM, Flower D, Lopez E, Kyle S, Meuth M, Curtin NJ, Helleday T. Bryant HE, et al. Nature. 2005 Apr 14;434(7035):913-7. doi: 10.1038/nature03443. Nature. 2005. PMID: 15829966 Free article.

2

Exploiting the Achilles heel of cancer: the therapeutic potential of poly(ADP-ribose) polymerase inhibitors in BRCA2-defective cancer.

Kyle S, Thomas HD, Mitchell J, Curtin NJ. Kyle S, et al. Br J Radiol. 2008 Oct;81 Spec No 1:S6-11. doi: 10.1259/bjr/99111297. Br J Radiol. 2008. PMID: 18820000

3

Poly(ADP-ribose) polymerase is hyperactivated in homologous recombination-defective cells.

Gottipati P, Vischioni B, Schultz N, Solomons J, Bryant HE, Djureinovic T, Issaeva N, Sleeth K, Sharma RA, Helleday T. Gottipati P, et al. Cancer Res. 2010 Jul 1;70(13):5389-98. doi: 10.1158/0008-5472.CAN-09-4716. Epub 2010 Jun 15. Cancer Res. 2010. PMID: 20551068 Free article.

4

Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy.

Farmer H, McCabe N, Lord CJ, Tutt AN, Johnson DA, Richardson TB, Santarosa M, Dillon KJ, Hickson I, Knights C, Martin NM, Jackson SP, Smith GC, Ashworth A. Farmer H, et al. Nature. 2005 Apr 14;434(7035):917-21. doi: 10.1038/nature03445. Nature. 2005. PMID: 15829967 Free article.

5

Replication fork stability confers chemoresistance in BRCA-deficient cells.

Ray Chaudhuri A, Callen E, Ding X, Gogola E, Duarte AA, Lee JE, Wong N, Lafarga V, Calvo JA, Panzarino NJ, John S, Day A, Crespo AV, Shen B, Starnes LM, de Ruiter JR, Daniel JA, Konstantinopoulos PA, Cortez D, Cantor SB, Fernandez-Capetillo O, Ge K, Jonkers J, Rottenberg S, Sharan SK, Nussenzweig A. Ray Chaudhuri A, et al. Nature. 2016 Jul 21;535(7612):382-7. doi: 10.1038/nature18325. Nature. 2016. PMID: 27443740 Free PMC article.

6

Synthetic lethality of PARP inhibition in cancers lacking BRCA1 and BRCA2 mutations.

Dedes KJ, Wilkerson PM, Wetterskog D, Weigelt B, Ashworth A, Reis-Filho JS. Dedes KJ, et al. Cell Cycle. 2011 Apr 15;10(8):1192-9. doi: 10.4161/cc.10.8.15273. Epub 2011 Apr 15. Cell Cycle. 2011. PMID: 21487248 Free PMC article.

7

Poly(ADP-ribose) polymerase (PARP-1) in homologous recombination and as a target for cancer therapy.

Helleday T, Bryant HE, Schultz N. Helleday T, et al. Cell Cycle. 2005 Sep;4(9):1176-8. doi: 10.4161/cc.4.9.2031. Epub 2005 Sep 12. Cell Cycle. 2005. PMID: 16123586 Review.

8

BRCA2-deficient CAPAN-1 cells are extremely sensitive to the inhibition of Poly (ADP-Ribose) polymerase: an issue of potency.

McCabe N, Lord CJ, Tutt AN, Martin NM, Smith GC, Ashworth A. McCabe N, et al. Cancer Biol Ther. 2005 Sep;4(9):934-6. doi: 10.4161/cbt.4.9.2141. Epub 2005 Sep 1. Cancer Biol Ther. 2005. PMID: 16251802

9

Inhibition of poly(ADP-ribose) glycohydrolase (PARG) specifically kills BRCA2-deficient tumor cells.

Fathers C, Drayton RM, Solovieva S, Bryant HE. Fathers C, et al. Cell Cycle. 2012 Mar 1;11(5):990-7. doi: 10.4161/cc.11.5.19482. Epub 2012 Mar 1. Cell Cycle. 2012. PMID: 22333589

10

6-thioguanine selectively kills BRCA2-defective tumors and overcomes PARP inhibitor resistance.

Issaeva N, Thomas HD, Djureinovic T, Jaspers JE, Stoimenov I, Kyle S, Pedley N, Gottipati P, Zur R, Sleeth K, Chatzakos V, Mulligan EA, Lundin C, Gubanova E, Kersbergen A, Harris AL, Sharma RA, Rottenberg S, Curtin NJ, Helleday T. Issaeva N, et al. Cancer Res. 2010 Aug 1;70(15):6268-76. doi: 10.1158/0008-5472.CAN-09-3416. Epub 2010 Jul 14. Cancer Res. 2010. PMID: 20631063 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Results by year

Text availability

Article attribute

Article type

Publication date

135 results

Results by year