Similar articles for PMID: 21785432

Year	Number of Results
2003	1
2004	2
2005	4
2006	3
2007	4
2008	4
2009	3
2010	6
2011	6
2012	9
2013	5
2014	6
2015	8
2016	9
2017	14
2018	6
2019	6
2020	13
2021	6
2022	9
2023	1
2024	0

1

HDAC6 inhibitors reverse axonal loss in a mouse model of mutant HSPB1-induced Charcot-Marie-Tooth disease.

d'Ydewalle C, Krishnan J, Chiheb DM, Van Damme P, Irobi J, Kozikowski AP, Vanden Berghe P, Timmerman V, Robberecht W, Van Den Bosch L. d'Ydewalle C, et al. Nat Med. 2011 Jul 24;17(8):968-74. doi: 10.1038/nm.2396. Nat Med. 2011. PMID: 21785432

2

Development of Improved HDAC6 Inhibitors as Pharmacological Therapy for Axonal Charcot-Marie-Tooth Disease.

Benoy V, Vanden Berghe P, Jarpe M, Van Damme P, Robberecht W, Van Den Bosch L. Benoy V, et al. Neurotherapeutics. 2017 Apr;14(2):417-428. doi: 10.1007/s13311-016-0501-z. Neurotherapeutics. 2017. PMID: 27957719 Free PMC article.

3

Bicyclic-Capped Histone Deacetylase 6 Inhibitors with Improved Activity in a Model of Axonal Charcot-Marie-Tooth Disease.

Shen S, Benoy V, Bergman JA, Kalin JH, Frojuello M, Vistoli G, Haeck W, Van Den Bosch L, Kozikowski AP. Shen S, et al. ACS Chem Neurosci. 2016 Feb 17;7(2):240-58. doi: 10.1021/acschemneuro.5b00286. Epub 2015 Dec 7. ACS Chem Neurosci. 2016. PMID: 26599234 Free PMC article.

4

HDAC6 is a therapeutic target in mutant GARS-induced Charcot-Marie-Tooth disease.

Benoy V, Van Helleputte L, Prior R, d'Ydewalle C, Haeck W, Geens N, Scheveneels W, Schevenels B, Cader MZ, Talbot K, Kozikowski AP, Vanden Berghe P, Van Damme P, Robberecht W, Van Den Bosch L. Benoy V, et al. Brain. 2018 Mar 1;141(3):673-687. doi: 10.1093/brain/awx375. Brain. 2018. PMID: 29415205 Free PMC article.

5

Novel HDAC6 Inhibitors Increase Tubulin Acetylation and Rescue Axonal Transport of Mitochondria in a Model of Charcot-Marie-Tooth Type 2F.

Adalbert R, Kaieda A, Antoniou C, Loreto A, Yang X, Gilley J, Hoshino T, Uga K, Makhija MT, Coleman MP. Adalbert R, et al. ACS Chem Neurosci. 2020 Feb 5;11(3):258-267. doi: 10.1021/acschemneuro.9b00338. Epub 2020 Jan 8. ACS Chem Neurosci. 2020. PMID: 31845794 Free PMC article.

6

Mutant small heat-shock protein 27 causes axonal Charcot-Marie-Tooth disease and distal hereditary motor neuropathy.

Evgrafov OV, Mersiyanova I, Irobi J, Van Den Bosch L, Dierick I, Leung CL, Schagina O, Verpoorten N, Van Impe K, Fedotov V, Dadali E, Auer-Grumbach M, Windpassinger C, Wagner K, Mitrovic Z, Hilton-Jones D, Talbot K, Martin JJ, Vasserman N, Tverskaya S, Polyakov A, Liem RK, Gettemans J, Robberecht W, De Jonghe P, Timmerman V. Evgrafov OV, et al. Nat Genet. 2004 Jun;36(6):602-6. doi: 10.1038/ng1354. Epub 2004 May 2. Nat Genet. 2004. PMID: 15122254

7

HDAC6 inhibition promotes α-tubulin acetylation and ameliorates CMT2A peripheral neuropathy in mice.

Picci C, Wong VSC, Costa CJ, McKinnon MC, Goldberg DC, Swift M, Alam NM, Prusky GT, Shen S, Kozikowski AP, Willis DE, Langley B. Picci C, et al. Exp Neurol. 2020 Jun;328:113281. doi: 10.1016/j.expneurol.2020.113281. Epub 2020 Mar 5. Exp Neurol. 2020. PMID: 32147437

8

Disruption of neurofilament network with aggregation of light neurofilament protein: a common pathway leading to motor neuron degeneration due to Charcot-Marie-Tooth disease-linked mutations in NFL and HSPB1.

Zhai J, Lin H, Julien JP, Schlaepfer WW. Zhai J, et al. Hum Mol Genet. 2007 Dec 15;16(24):3103-16. doi: 10.1093/hmg/ddm272. Epub 2007 Sep 19. Hum Mol Genet. 2007. PMID: 17881652

9

A Charcot-Marie-Tooth-Causing Mutation in HSPB1 Decreases Cell Adaptation to Repeated Stress by Disrupting Autophagic Clearance of Misfolded Proteins.

Zhang X, Qiao Y, Han R, Gao Y, Yang X, Zhang Y, Wan Y, Yu W, Pan X, Xing J. Zhang X, et al. Cells. 2022 Sep 15;11(18):2886. doi: 10.3390/cells11182886. Cells. 2022. PMID: 36139461 Free PMC article.

10

Human HSPB1 mutation recapitulates features of distal hereditary motor neuropathy (dHMN) in Drosophila.

Kang KH, Han JE, Hong YB, Nam SH, Choi BO, Koh H. Kang KH, et al. Biochem Biophys Res Commun. 2020 Jan 1;521(1):220-226. doi: 10.1016/j.bbrc.2019.10.110. Epub 2019 Oct 17. Biochem Biophys Res Commun. 2020. PMID: 31630804

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