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8387545,1375719,8570209,8309256,2170850,8395310,1312695,8302850,1849600,1325570,8384553,1650447,7697468,8274203,7719245,7849296,8238249,9365539,8142621,18558288,1320955,1319828,1656889,1323988,8057672,1327453,18206542,18683144,8721678,9070655,15860361,7920173,11066449,19027486,1851240,1848017,1353379,8755206,1318462,1314166,8727344,1312109,16772124,8622986,9206036,1849030,1911035,8625266,2175343,8618456,7987829,1668609,1372989,1850498,2173802,8385249,8161469,1701231,1601819,1667950,8180390,1310153,7648936,1652369,12691149,7519869,8158844,8380300,9164186,8139100,8285119,8387477,8952164,10942371,8400225,1353552,1339190,1652368,23382200,1313768,20193853,1453773,1720570,1318464,1323928,9494608,7632962,8562957,1310060,1317574,17988991,1487198,8574167,1313714,18000064,7680887,2554072,10484977,10360373,23363773,9096691,34042280,8402546,1317727,9266946,21617563,1849758,9288109,12357344,8394480,9278395,8639801,1835902,12885463,1337847,7641768,3102433,8541544,21378481,10441338,7736436,8044771,7926984,19100514,8605120,9276968,1330303,1311253,10942370,17217037,8386953,11696577,8392400,8144129,1375840,3085877,24942021,2218500,7914242,11090081,19477513,7918086,7908146,10500192,12357347,1303259,7736444,7658728,7716676,19190979,8043428,23651981,1568226,8260693,1317749,8982049,1360562,25639817,12885460,8180596,9488621,20682396,8385082,29653010,7553583,12505260,8394219,29350080,21927800,1382572,35454359,20633765,10634650,25790901,22852214,10347551,11964310,9226181,7682097,25759405,8339294,20236758,2620272,25284716,20471513,10381496,8208541,8188297,9664337,1648546,10688654,16044313,8781440,10803535,23927396,1701354,29845460,27459859,7939191,25641487,17712046,20513534,19903674,7507700,7949141,8547645,7552583,2790765,23664605,26342691,8535190,11672771,26469919,2823022,1562718,10225671,23287866,7710454,7720600,1327285,2838781,8892693,7615044,10812165,8172191,9115966,19142993,8388166,7688554,10497277,20189646,9530334,20113841,16056248,8210653,8095789,1695704,7832190,1720549,1655630,1911341,16341036,15622742,23147462,2538684,3422330,24310817,9460497,11401094,8689611,8589015,14645547,11114710,21350831,12100154,1317215,8487585,9851086,7812004,11114709,1824246,15313893,23991619,7892256,8712802,8751468,2066549,1797083,8111744,15239396,10203104,2357686,10565300,34270998,8168591,2268582,10199205,8080665,3501046,1551085,8281523,1373309,22186000,11801315,2278973,16631470,21750086,1911349,9973944,17405265,14527952,7688552,8518183,8515790,22972688,9766493,8847902,8193365,31207999,2536901,9371524,1286530,8580825,2543068,1335685,20434005,1756499,8439701,32984885,12419579,18156746,27193600,3456488,19128831,22205181,7623123,8152726,2172793,12094260,10587705,12935930,8352233,10433962,23250036,25860246,8082094,20060166,8058765,2825962,1995093,12645658,1281693,8049655,15218975,11561157,8427956,28179318,12795845,20855112,2546626,3203292,2265401,10322484,1396583,8057659,1740340,12505261,8042616,6589608,8847903,11516096,8506328,2896388,1756485,8234289,12550765,12412372,7658717,7502634,2439153,22822476,25076892,33116634,2013982,3463403,16397222,3109734,8124205,9207104,12075932,8016145,27302179,2844649,1756477,1868032,34356051,3857110,23770155,1630450,1407980,8790148,2174466,1438235,9279368,1339395,7888665,2844650,1884013,3478130,18256686,15358589,2915920,28385775,2491897,2766650,8383526,8480488,10700873,22181564,6573949,6962753,26622430,7983997,1829960,2741926,8292523,8758302,1584812,24410923,1958492,7817703,6584204,21729689,32414556,2437586,2174108,7579425,24759014,31515708,21218723,10516754,1332705,7951006,2737676,10936873,15218416,9710637,1860835,2541430,22555178,10997972,20884714,8309246,25130873,8514604,7679509,7647012,8027679,9595039,8824722,2230879,8045381,8616781,7656208,9689933,25892894,8483267,2157210,7490103,3258177,26347920,26802620,3466872,23195952,8388706,8914610,1768623,7688551,27313723,12872155,29568099,12472288,10673045,22346000,8868093,17568815,9003482,1863199,14521715,1922059,8382622,276386,8383424,8329709,1505955,2172659,1849262,10468848,3929142,7990767,35900907,26206695,8914611,8141124,26351594,8537771,8619133,9111557,2370860,1281998,2527802,9371394,30632861,9618176,12781455,8361230,34268555,3499671,10997330,8754158,6580050,23049403,1797085,1394096,22911923,21956236,8384099,8499638,2037297,1972563,3540949,11352657,26266276,7542910,3455864,32908049,1321791,25606057,8997125,1369415,6093263,7509627,35125731,24416501,2026422,2014798,271143,1505991,35495123,3216675,3455829,2487149,2553496,7438112,3163742,15218965,6945293,8500793,1668322,1648980,10192433,15962019,23839334,2046384,8638633,21606962,8946209,6587773,8391236,22848226,8490178,1330883,20679386,8019966,21479585,1988964,10362256,8262519,8052649,8221619,8914608,3622011,2004757,8143192,2646008,34804401,8950582,32590818,30628160,7958967,1377686,2024246,8032421,830097,1963458,3978592,24009642,24798252,26722261,36168835,1765382,31027502,2153628,30863166,31709264,19197738,15223653,8428753,27539154,10778215,1682582,18464121,1395716,28092893,16717458,23275121,1333589,10557070,32337199,1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Rearrangements of the retinoic acid receptor alpha and promyelocytic leukemia zinc finger genes resulting from t(11;17)(q23;q21) in a patient with acute promyelocytic leukemia.

Chen SJ, Zelent A, Tong JH, Yu HQ, Wang ZY, Derré J, Berger R, Waxman S, Chen Z. Chen SJ, et al. J Clin Invest. 1993 May;91(5):2260-7. doi: 10.1172/JCI116453. J Clin Invest. 1993. PMID: 8387545 Free PMC article.

Occurrence of distinct PML-RAR-alpha fusion gene isoforms in patients with acute promyelocytic leukemia detected by reverse transcriptase/polymerase chain reaction.

Chen SJ, Chen Z, Chen A, Tong JH, Dong S, Wang ZY, Waxman S, Zelent A. Chen SJ, et al. Oncogene. 1992 Jun;7(6):1223-32. Oncogene. 1992. PMID: 1375719

Reduced and altered DNA-binding and transcriptional properties of the PLZF-retinoic acid receptor-alpha chimera generated in t(11;17)-associated acute promyelocytic leukemia.

Licht JD, Shaknovich R, English MA, Melnick A, Li JY, Reddy JC, Dong S, Chen SJ, Zelent A, Waxman S. Licht JD, et al. Oncogene. 1996 Jan 18;12(2):323-36. Oncogene. 1996. PMID: 8570209

Poor response to all-trans retinoic acid therapy in a t(11;17) PLZF/RAR alpha patient.

Guidez F, Huang W, Tong JH, Dubois C, Balitrand N, Waxman S, Michaux JL, Martiat P, Degos L, Chen Z, et al. Guidez F, et al. Leukemia. 1994 Feb;8(2):312-7. Leukemia. 1994. PMID: 8309256

The t(15;17) translocation of acute promyelocytic leukaemia fuses the retinoic acid receptor alpha gene to a novel transcribed locus.

de Thé H, Chomienne C, Lanotte M, Degos L, Dejean A. de Thé H, et al. Nature. 1990 Oct 11;347(6293):558-61. doi: 10.1038/347558a0. Nature. 1990. PMID: 2170850

[Molecular study on the distinct isoforms of PML-RAR alpha fusion gene transcripts in acute promyelocytic leukemia].

Geng JP. Geng JP. Zhonghua Yi Xue Za Zhi. 1993 Apr;73(4):197-200, 252. Zhonghua Yi Xue Za Zhi. 1993. PMID: 8395310 Chinese.

Molecular rearrangements of the MYL gene in acute promyelocytic leukemia (APL, M3) define a breakpoint cluster region as well as some molecular variants.

Tong JH, Dong S, Geng JP, Huang W, Wang ZY, Sun GL, Chen SJ, Chen Z, Larsen CJ, Berger R. Tong JH, et al. Oncogene. 1992 Feb;7(2):311-6. Oncogene. 1992. PMID: 1312695

PLZF-RAR alpha fusion proteins generated from the variant t(11;17)(q23;q21) translocation in acute promyelocytic leukemia inhibit ligand-dependent transactivation of wild-type retinoic acid receptors.

Chen Z, Guidez F, Rousselot P, Agadir A, Chen SJ, Wang ZY, Degos L, Zelent A, Waxman S, Chomienne C. Chen Z, et al. Proc Natl Acad Sci U S A. 1994 Feb 1;91(3):1178-82. doi: 10.1073/pnas.91.3.1178. Proc Natl Acad Sci U S A. 1994. PMID: 8302850 Free PMC article.

Rearrangement of the retinoic acid receptor gene in acute promyelocytic leukemia.

Chang KS, Trujillo JM, Ogura T, Castiglione CM, Kidd KK, Zhao SR, Freireich EJ, Stass SA. Chang KS, et al. Leukemia. 1991 Mar;5(3):200-4. Leukemia. 1991. PMID: 1849600

[Retinoic acid receptor alpha gene in t (15; 17) APL].

Takashima T, Misawa S. Takashima T, et al. Nihon Rinsho. 1992 Jun;50(6):1363-8. Nihon Rinsho. 1992. PMID: 1325570 Japanese.

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