Human Neutrophils Produce Antifungal Extracellular Vesicles against Aspergillus fumigatus.
Shopova IA, Belyaev I, Dasari P, Jahreis S, Stroe MC, Cseresnyés Z, Zimmermann AK, Medyukhina A, Svensson CM, Krüger T, Szeifert V, Nietzsche S, Conrad T, Blango MG, Kniemeyer O, von Lilienfeld-Toal M, Zipfel PF, Ligeti E, Figge MT, Brakhage AA.
Shopova IA, et al.
mBio. 2020 Apr 14;11(2):e00596-20. doi: 10.1128/mBio.00596-20.
mBio. 2020.
PMID: 32291301
Free PMC article.
To assess as a proof of concept whether the antimicrobial proteins found in afEVs might contribute to growth inhibition of hyphae when present in the fungal cytoplasm, two human proteins enriched in afEVs, cathepsin G and azurocidin, were heterologously expressed in fungal …
To assess as a proof of concept whether the antimicrobial proteins found in afEVs might contribute to growth inhibition of hyphae when prese …