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Neuronal aldosterone elicits a distinct genomic response in pain signaling molecules contributing to inflammatory pain.
Shaqura M, Li L, Mohamed DM, Li X, Treskatsch S, Buhrmann C, Shakibaei M, Beyer A, Mousa SA, Schäfer M. Shaqura M, et al. J Neuroinflammation. 2020 Jun 12;17(1):183. doi: 10.1186/s12974-020-01864-8. J Neuroinflammation. 2020. PMID: 32532285 Free PMC article.
BACKGROUND: Recently, mineralocorticoid receptors (MR) were identified in peripheral nociceptive neurons, and their acute antagonism was responsible for immediate and short-lasting (non-genomic) antinociceptive effects. ...METHODS: Here, we investigate whether endogenous a …
BACKGROUND: Recently, mineralocorticoid receptors (MR) were identified in peripheral nociceptive neurons, and their acute antagonism …