Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1990 1
2013 3
2014 2
2015 1
2019 1
2022 1
2024 2

Text availability

Article attribute

Article type

Publication date

Search Results

11 results

Results by year

Filters applied: . Clear all
Your search was processed without automatic term mapping because it retrieved zero results.
Page 1
Did you mean s j legg (585 results)?
Hypnozoite dynamics for Plasmodium vivax malaria: The epidemiological effects of radical cure.
Mehra S, Stadler E, Khoury D, McCaw JM, Flegg JA. Mehra S, et al. J Theor Biol. 2022 Mar 21;537:111014. doi: 10.1016/j.jtbi.2022.111014. Epub 2022 Jan 10. J Theor Biol. 2022. PMID: 35016895
Relapsing infections, driven by a reservoir of liver-stage parasites known as hypnozoites, present unique challenges for the control of P. vivax malaria. Following indeterminate dormancy periods, hypnozoites may activate to trigger relapses. ...Our work thus contributes to …
Relapsing infections, driven by a reservoir of liver-stage parasites known as hypnozoites, present unique challenges for the control of P …
Spread of artemisinin resistance in Plasmodium falciparum malaria.
Ashley EA, Dhorda M, Fairhurst RM, Amaratunga C, Lim P, Suon S, Sreng S, Anderson JM, Mao S, Sam B, Sopha C, Chuor CM, Nguon C, Sovannaroth S, Pukrittayakamee S, Jittamala P, Chotivanich K, Chutasmit K, Suchatsoonthorn C, Runcharoen R, Hien TT, Thuy-Nhien NT, Thanh NV, Phu NH, Htut Y, Han KT, Aye KH, Mokuolu OA, Olaosebikan RR, Folaranmi OO, Mayxay M, Khanthavong M, Hongvanthong B, Newton PN, Onyamboko MA, Fanello CI, Tshefu AK, Mishra N, Valecha N, Phyo AP, Nosten F, Yi P, Tripura R, Borrmann S, Bashraheil M, Peshu J, Faiz MA, Ghose A, Hossain MA, Samad R, Rahman MR, Hasan MM, Islam A, Miotto O, Amato R, MacInnis B, Stalker J, Kwiatkowski DP, Bozdech Z, Jeeyapant A, Cheah PY, Sakulthaew T, Chalk J, Intharabut B, Silamut K, Lee SJ, Vihokhern B, Kunasol C, Imwong M, Tarning J, Taylor WJ, Yeung S, Woodrow CJ, Flegg JA, Das D, Smith J, Venkatesan M, Plowe CV, Stepniewska K, Guerin PJ, Dondorp AM, Day NP, White NJ; Tracking Resistance to Artemisinin Collaboration (TRAC). Ashley EA, et al. N Engl J Med. 2014 Jul 31;371(5):411-23. doi: 10.1056/NEJMoa1314981. N Engl J Med. 2014. PMID: 25075834 Free PMC article. Clinical Trial.
Slowly clearing infections (parasite clearance half-life >5 hours), strongly associated with single point mutations in the "propeller" region of the P. falciparum kelch protein gene on chromosome 13 (kelch13), were detected throughout mainland Southeast Asia from southe …
Slowly clearing infections (parasite clearance half-life >5 hours), strongly associated with single point mutations in the "propeller" re …
Evaluating the novel added value of neurophysiological pain sensitivity within the fear-avoidance model of pain.
Uddin Z, Woznowski-Vu A, Flegg D, Aternali A, Wickens R, Wideman TH. Uddin Z, et al. Eur J Pain. 2019 May;23(5):957-972. doi: 10.1002/ejp.1364. Epub 2019 Jan 30. Eur J Pain. 2019. PMID: 30648781

RESULTS: A series of hierarchical regression analyses revealed that after controlling for the psychological predictors of the FAM, indices of pain sensitivity significantly predicted 4 of the 5 FAM-related outcomes (p < 0.05). Depression was the only outcome not signifi

…
RESULTS: A series of hierarchical regression analyses revealed that after controlling for the psychological predictors of the FAM, indices o …
Systematic Review and Geospatial Modeling of Molecular Markers of Resistance to Artemisinins and Sulfadoxine-Pyrimethamine in Plasmodium falciparum in India.
Nain M, Dhorda M, Flegg JA, Gupta A, Harrison LE, Singh-Phulgenda S, Otienoburu SD, Harriss E, Bharti PK, Behera B, Rahi M, Guerin PJ, Sharma A. Nain M, et al. Am J Trop Med Hyg. 2024 Apr 2;110(5):910-920. doi: 10.4269/ajtmh.23-0631. Print 2024 May 1. Am J Trop Med Hyg. 2024. PMID: 38574550 Free PMC article.
The sample collection from the studies identified from this search was conducted between 1994 and 2020, and these studies were published between 1994 and 2022. In all, Plasmodium falciparum Kelch13 (PfK13), P. falciparum dihydropteroate synthase, and P. falciparum d …
The sample collection from the studies identified from this search was conducted between 1994 and 2020, and these studies were published bet …
Spatiotemporal mathematical modelling of mutations of the dhps gene in African Plasmodium falciparum.
Flegg JA, Patil AP, Venkatesan M, Roper C, Naidoo I, Hay SI, Sibley CH, Guerin PJ. Flegg JA, et al. Malar J. 2013 Jul 17;12:249. doi: 10.1186/1475-2875-12-249. Malar J. 2013. PMID: 23866695 Free PMC article.
Here a mathematical model was developed to map the spatiotemporal trends in the distribution of mutations in the P. falciparum dihydropteroate synthetase (dhps) gene that confer resistance to the anti-malarial sulphadoxine, and are a useful marker for the combination of al …
Here a mathematical model was developed to map the spatiotemporal trends in the distribution of mutations in the P. falciparum dihydr …
A hybrid transmission model for Plasmodium vivax accounting for superinfection, immunity and the hypnozoite reservoir.
Mehra S, Taylor PG, McCaw JM, Flegg JA. Mehra S, et al. J Math Biol. 2024 May 21;89(1):7. doi: 10.1007/s00285-024-02088-7. J Math Biol. 2024. PMID: 38772937 Free PMC article.
Relapses, arising from hypnozoite activation events, comprise the majority of the blood-stage infection burden, with implications for the acquisition of immunity and the distribution of superinfection. Here, we construct a novel model for the transmission of P. vivax that …
Relapses, arising from hypnozoite activation events, comprise the majority of the blood-stage infection burden, with implications for the ac …
Potential risks of ultraviolet radiation in HIV infection.
Flegg PJ. Flegg PJ. Int J STD AIDS. 1990 Jan;1(1):46-8. doi: 10.1177/095646249000100111. Int J STD AIDS. 1990. PMID: 2099198
HIV seropositives had greater recreational UVR exposure than controls: 12/58 versus 4/61 had regular use of a sunbed (P less than 0.05), and experienced 11.6 weeks versus 9.5 weeks of prolonged natural UVR exposure (P = 0.056) over a four-year period. ...
HIV seropositives had greater recreational UVR exposure than controls: 12/58 versus 4/61 had regular use of a sunbed (P less than 0.0 …
Longitudinal study assessing the return of chloroquine susceptibility of Plasmodium falciparum in isolates from travellers returning from West and Central Africa, 2000-2011.
Gharbi M, Flegg JA, Hubert V, Kendjo E, Metcalf JE, Bertaux L, Guérin PJ, Le Bras J; Members of the French National Reference Centre for Imported Malaria Study; Aboubaca A, Agnamey P, Angoulvant A, Barbut P, Basset D, Belkadi G, Bellanger AP, Bemba D, Benoit-Vica F, Berry A, Bigel ML, Bonhomme J, Botterel F, Bouchaud O, Bougnoux ME, Bourée P, Bourgeois N, Branger C, Bret L, Buret B, Casalino E, Chevrier S, Conquere de Monbrison F, Cuisenier B, Danis M, Darde ML, De Gentile L, Delarbre JM, Delaunay P, Delaval A, Desoubeaux G, Develoux M, Dunand J, Durand R, Eloy O, Fauchet N, Faugere B, Faye A, Fenneteau O, Flori P, Fontrouge M, Garabedian C, Gayandrieu F, Godineau N, Houzé P, Houzé S, Hurst JP, Ichou H, Lachaud L, Lebuisson A, Lefevre M, LeGuern AS, Le Moal G, Lusina D, Machouart MC, Malvy D, Matheron S, Maubon D, Mechali D, Megarbane B, Menard G, Millon L, Aiach MM, Minodier P, Morelle C, Nevez G, Parola P, Parzy D, Patey O, Patoz P, Penn P, Perignon A, Picot S, Pilo JE, Poilane I, Pons D, Poupart M, Pradines B, Raffenot D, Rapp C, Receveur MC, Sarfati C, Senghor Y, Simon F, Siriez JY, Taudon N, Thellier M, Thouvenin M, Toubas D. Gharbi M, et al. Malar J. 2013 Jan 25;12:35. doi: 10.1186/1475-2875-12-35. Malar J. 2013. PMID: 23351608 Free PMC article.

Meanwhile, CQ use among children significantly deceased in this region (fixed effects slope = -0.3, p < 10-3). CONCLUSIONS: An increase in CQ susceptibility following official withdrawal of the drug was observed in travellers returning from West and Central African coun

…

Meanwhile, CQ use among children significantly deceased in this region (fixed effects slope = -0.3, p < 10-3). CONCLUSIONS: An inc

…
Baseline data of parasite clearance in patients with falciparum malaria treated with an artemisinin derivative: an individual patient data meta-analysis.
WWARN Parasite Clearance Study Group; Abdulla S, Ashley EA, Bassat Q, Bethell D, Björkman A, Borrmann S, D'Alessandro U, Dahal P, Day NP, Diakite M, Djimde AA, Dondorp AM, Duong S, Edstein MD, Fairhurst RM, Faiz MA, Falade C, Flegg JA, Fogg C, Gonzalez R, Greenwood B, Guérin PJ, Guthmann JP, Hamed K, Hien TT, Htut Y, Juma E, Lim P, Mårtensson A, Mayxay M, Mokuolu OA, Moreira C, Newton P, Noedl H, Nosten F, Ogutu BR, Onyamboko MA, Owusu-Agyei S, Phyo AP, Premji Z, Price RN, Pukrittayakamee S, Ramharter M, Sagara I, Se Y, Suon S, Stepniewska K, Ward SA, White NJ, Winstanley PA. WWARN Parasite Clearance Study Group, et al. Malar J. 2015 Sep 22;14:359. doi: 10.1186/s12936-015-0874-1. Malar J. 2015. PMID: 26390866 Free PMC article.
Long PC1/2 (HR = 2.91, 95 % CI 1.95-4.34 for twofold increase, p < 0.001) and high initial parasitaemia (HR = 2.23, 95 % CI 1.44-3.45 for tenfold increase, p < 0.001) were associated independently with an increased risk of recrudescence. ...

Long PC1/2 (HR = 2.91, 95 % CI 1.95-4.34 for twofold increase, p < 0.001) and high initial parasitaemia (HR = 2.23, 95 % CI 1.44-3

…
Impact of postoperative non-steroidal anti-inflammatory drugs on adverse events after gastrointestinal surgery.
STARSurg Collaborative. STARSurg Collaborative. Br J Surg. 2014 Oct;101(11):1413-23. doi: 10.1002/bjs.9614. Epub 2014 Aug 4. Br J Surg. 2014. PMID: 25091299
Treatment with NSAIDs was associated with a reduction in overall complications (OR 0.72, 95 per cent confidence interval 0.52 to 0.99; P = 0.041). This effect predominantly comprised a reduction in minor complications with high-dose NSAIDs (OR 0.57, 0.39 to 0.89; P …
Treatment with NSAIDs was associated with a reduction in overall complications (OR 0.72, 95 per cent confidence interval 0.52 to 0.99; P …
11 results