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Year Number of Results
2012 2
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2015 2
2016 1
2018 5
2019 2
2020 5
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2022 3
2024 1

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24 results

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Page 1
Prevention and Management of Delirium in the Intensive Care Unit.
Mart MF, Williams Roberson S, Salas B, Pandharipande PP, Ely EW. Mart MF, et al. Semin Respir Crit Care Med. 2021 Feb;42(1):112-126. doi: 10.1055/s-0040-1710572. Epub 2020 Aug 3. Semin Respir Crit Care Med. 2021. PMID: 32746469 Free PMC article.
Further refinements of therapeutic options, from drugs to rehabilitation, are current areas ripe for study to improve the short- and long-term outcomes of critically ill patients with delirium....
Further refinements of therapeutic options, from drugs to rehabilitation, are current areas ripe for study to improve the short- and long- …
Long-term cognitive impairment after critical illness.
Pandharipande PP, Girard TD, Jackson JC, Morandi A, Thompson JL, Pun BT, Brummel NE, Hughes CG, Vasilevskis EE, Shintani AK, Moons KG, Geevarghese SK, Canonico A, Hopkins RO, Bernard GR, Dittus RS, Ely EW; BRAIN-ICU Study Investigators. Pandharipande PP, et al. N Engl J Med. 2013 Oct 3;369(14):1306-16. doi: 10.1056/NEJMoa1301372. N Engl J Med. 2013. PMID: 24088092 Free PMC article. Clinical Trial.
CONCLUSIONS: Patients in medical and surgical ICUs are at high risk for long-term cognitive impairment. A longer duration of delirium in the hospital was associated with worse global cognition and executive function scores at 3 and 12 months. ...
CONCLUSIONS: Patients in medical and surgical ICUs are at high risk for long-term cognitive impairment. A longer duration of delirium …
Fluid Management in Acute Respiratory Distress Syndrome.
Casey JD, Semler MW, Rice TW. Casey JD, et al. Semin Respir Crit Care Med. 2019 Feb;40(1):57-65. doi: 10.1055/s-0039-1685206. Epub 2019 May 6. Semin Respir Crit Care Med. 2019. PMID: 31060088 Free PMC article. Review.
These physiologic observations have led to a series of studies examining the impact of fluid management on the development of, resolution of, survival from, and long-term outcomes from ARDS. While questions remain, the current literature makes it clear that fluid managemen …
These physiologic observations have led to a series of studies examining the impact of fluid management on the development of, resolution of …
The long-lasting effects of the acute respiratory distress syndrome.
Mart MF, Ware LB. Mart MF, et al. Expert Rev Respir Med. 2020 Jun;14(6):577-586. doi: 10.1080/17476348.2020.1743182. Epub 2020 Mar 17. Expert Rev Respir Med. 2020. PMID: 32168460 Free PMC article. Review.
A summary of is presented here to outline the sequelae of ARDS and their risk factors with a focus on the limited but growing research into possible therapies. Long term sequelae of ARDS commonly identified in the literature include long-term cognitive impairment, p …
A summary of is presented here to outline the sequelae of ARDS and their risk factors with a focus on the limited but growing research into …
Understanding and reducing disability in older adults following critical illness.
Brummel NE, Balas MC, Morandi A, Ferrante LE, Gill TM, Ely EW. Brummel NE, et al. Crit Care Med. 2015 Jun;43(6):1265-75. doi: 10.1097/CCM.0000000000000924. Crit Care Med. 2015. PMID: 25756418 Free PMC article. Review.
OBJECTIVE: To review how disability can develop in older adults with critical illness and to explore ways to reduce long-term disability following critical illness. DATA SOURCES: We searched PubMed, CINAHL, Web of Science and Google Scholar for studies reporting disability …
OBJECTIVE: To review how disability can develop in older adults with critical illness and to explore ways to reduce long-term disabil …
Dose, Timing, and Type of Infant Antibiotic Use and the Risk of Childhood Asthma.
Donovan BM, Abreo A, Ding T, Gebretsadik T, Turi KN, Yu C, Ding J, Dupont WD, Stone CA, Hartert TV, Wu P. Donovan BM, et al. Clin Infect Dis. 2020 Apr 10;70(8):1658-1665. doi: 10.1093/cid/ciz448. Clin Infect Dis. 2020. PMID: 31149702 Free PMC article.
We aimed to evaluate comprehensively and simultaneously the impact of dose, timing, and type of infant antibiotic use on the risk of childhood asthma. METHODS: Singleton, term-birth, non-low-birth-weight, and otherwise healthy children enrolled in the Tenness …
We aimed to evaluate comprehensively and simultaneously the impact of dose, timing, and type of infant antibiotic use on the risk of childho …
Socioeconomic Factors and Intensive Care Unit-Related Cognitive Impairment.
Haddad DN, Mart MF, Wang L, Lindsell CJ, Raman R, Nordness MF, Sharp KW, Pandharipande PP, Girard TD, Ely EW, Patel MB. Haddad DN, et al. Ann Surg. 2020 Oct;272(4):596-602. doi: 10.1097/SLA.0000000000004377. Ann Surg. 2020. PMID: 32932314 Free PMC article.
OBJECTIVE: We aimed to identify socioeconomic and clinical risk factors for post-intensive care unit (ICU)-related long-term cognitive impairment (LTCI). SUMMARY BACKGROUND DATA: After delirium during ICU stay, LTCI has been increasingly recognized, but without attention t …
OBJECTIVE: We aimed to identify socioeconomic and clinical risk factors for post-intensive care unit (ICU)-related long-term cognitiv …
Neutropenia Associated with Long-Term Ceftaroline Use.
LaVie KW, Anderson SW, O'Neal HR Jr, Rice TW, Saavedra TC, O'Neal CS. LaVie KW, et al. Antimicrob Agents Chemother. 2015 Oct 26;60(1):264-9. doi: 10.1128/AAC.01471-15. Print 2016 Jan. Antimicrob Agents Chemother. 2015. PMID: 26503657 Free PMC article.
Effect of Early Balanced Crystalloids Before ICU Admission on Sepsis Outcomes.
Jackson KE, Wang L, Casey JD, Bernard GR, Self WH, Rice TW, Semler MW; SMART Investigators and the Pragmatic Critical Care Research Group. Jackson KE, et al. Chest. 2021 Feb;159(2):585-595. doi: 10.1016/j.chest.2020.08.2068. Epub 2020 Aug 31. Chest. 2021. PMID: 32882244 Free PMC article. Clinical Trial.
We performed logistic regression modeling for 30-day in-hospital mortality with an interaction term between randomized group (balanced crystalloids vs saline) and study period (ICU-only period vs ED and ICU period). ...
We performed logistic regression modeling for 30-day in-hospital mortality with an interaction term between randomized group (balance …
Oxygen-Saturation Targets and Cognitive and Functional Outcomes in Mechanically Ventilated Adults.
Mart MF, Semler MW, Jenkins CA, Wang G, Casey JD, Ely EW, Jackson JC, Kiehl AL, Bryant PT, Pugh SK, Wang L, DeMasi S, Rice TW, Bernard GR, Freundlich RE, Self WH, Han JH. Mart MF, et al. Am J Respir Crit Care Med. 2024 Apr 1;209(7):861-870. doi: 10.1164/rccm.202310-1826OC. Am J Respir Crit Care Med. 2024. PMID: 38285550
Rationale: Among mechanically ventilated critically ill adults, the PILOT (Pragmatic Investigation of Optimal Oxygen Targets) trial demonstrated no difference in ventilator-free days among lower, intermediate, and higher oxygen-saturation targets. The effects on long-term
Rationale: Among mechanically ventilated critically ill adults, the PILOT (Pragmatic Investigation of Optimal Oxygen Targets) trial demonstr …
24 results