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Year Number of Results
2013 6
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2016 9
2017 10
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2019 5
2020 3
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2023 1
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65 results

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Page 1
Ventral Hernia Management: Expert Consensus Guided by Systematic Review.
Liang MK, Holihan JL, Itani K, Alawadi ZM, Gonzalez JR, Askenasy EP, Ballecer C, Chong HS, Goldblatt MI, Greenberg JA, Harvin JA, Keith JN, Martindale RG, Orenstein S, Richmond B, Roth JS, Szotek P, Towfigh S, Tsuda S, Vaziri K, Berger DH. Liang MK, et al. Ann Surg. 2017 Jan;265(1):80-89. doi: 10.1097/SLA.0000000000001701. Ann Surg. 2017. PMID: 28009730
Nonoperative management was considered to have a low-risk of short-term morbidity (grade C). Mesh reinforcement was recommended for repair of hernias 2 cm (grade A). ...CONCLUSIONS: Although there was consensus, supported by grade A-C evidence, on patient selection, the sa …
Nonoperative management was considered to have a low-risk of short-term morbidity (grade C). Mesh reinforcement was recommended for r …
Dabrafenib plus trametinib in patients with BRAF V600E-mutant anaplastic thyroid cancer: updated analysis from the phase II ROAR basket study.
Subbiah V, Kreitman RJ, Wainberg ZA, Cho JY, Schellens JHM, Soria JC, Wen PY, Zielinski CC, Cabanillas ME, Boran A, Ilankumaran P, Burgess P, Romero Salas T, Keam B. Subbiah V, et al. Ann Oncol. 2022 Apr;33(4):406-415. doi: 10.1016/j.annonc.2021.12.014. Epub 2022 Jan 10. Ann Oncol. 2022. PMID: 35026411 Free PMC article. Clinical Trial.
CONCLUSIONS: These updated results confirm the substantial clinical benefit and manageable toxicity of dabrafenib plus trametinib in BRAF V600E-mutant ATC. Dabrafenib plus trametinib notably improved long-term survival and represents a meaningful treatment option for this …
CONCLUSIONS: These updated results confirm the substantial clinical benefit and manageable toxicity of dabrafenib plus trametinib in BRAF V6 …
Long-Term Prognostic Risk After Neoadjuvant Chemotherapy Associated With Residual Cancer Burden and Breast Cancer Subtype.
Symmans WF, Wei C, Gould R, Yu X, Zhang Y, Liu M, Walls A, Bousamra A, Ramineni M, Sinn B, Hunt K, Buchholz TA, Valero V, Buzdar AU, Yang W, Brewster AM, Moulder S, Pusztai L, Hatzis C, Hortobagyi GN. Symmans WF, et al. J Clin Oncol. 2017 Apr 1;35(10):1049-1060. doi: 10.1200/JCO.2015.63.1010. Epub 2017 Jan 30. J Clin Oncol. 2017. PMID: 28135148 Free PMC article.
Purpose To determine the long-term prognosis in each phenotypic subset of breast cancer related to residual cancer burden (RCB) after neoadjuvant chemotherapy alone, or with concurrent human epidermal growth factor receptor 2 (HER2)-targeted treatment. ...Estimates of 10-y …
Purpose To determine the long-term prognosis in each phenotypic subset of breast cancer related to residual cancer burden (RCB) after …
Oncometabolic Tracks in the Heart.
Taegtmeyer H, Karlstaedt A, Rees ML, Davogustto G. Taegtmeyer H, et al. Circ Res. 2017 Jan 20;120(2):267-269. doi: 10.1161/CIRCRESAHA.116.310115. Circ Res. 2017. PMID: 28104766 Free PMC article. Review.
The term cancer and the heart is readily associated with the cardiotoxicity of antineoplastic agents, such as anthracyclines or receptor tyrosine kinase inhibitors. ...
The term cancer and the heart is readily associated with the cardiotoxicity of antineoplastic agents, such as anthracyclines or recep …
Advances in Targeting RET-Dependent Cancers.
Subbiah V, Cote GJ. Subbiah V, et al. Cancer Discov. 2020 Apr;10(4):498-505. doi: 10.1158/2159-8290.CD-19-1116. Epub 2020 Feb 24. Cancer Discov. 2020. PMID: 32094155 Free PMC article. Review.
Questions that clearly need to be addressed relate to the ability to maintain long-term inhibition of tumor cell growth, how to prepare for the potential mechanisms of acquired resistance, and the development of next-generation selective RET inhibitors....
Questions that clearly need to be addressed relate to the ability to maintain long-term inhibition of tumor cell growth, how to prepa …
Effect of Therapeutic Hypothermia Initiated After 6 Hours of Age on Death or Disability Among Newborns With Hypoxic-Ischemic Encephalopathy: A Randomized Clinical Trial.
Laptook AR, Shankaran S, Tyson JE, Munoz B, Bell EF, Goldberg RN, Parikh NA, Ambalavanan N, Pedroza C, Pappas A, Das A, Chaudhary AS, Ehrenkranz RA, Hensman AM, Van Meurs KP, Chalak LF, Khan AM, Hamrick SEG, Sokol GM, Walsh MC, Poindexter BB, Faix RG, Watterberg KL, Frantz ID 3rd, Guillet R, Devaskar U, Truog WE, Chock VY, Wyckoff MH, McGowan EC, Carlton DP, Harmon HM, Brumbaugh JE, Cotten CM, Sánchez PJ, Hibbs AM, Higgins RD; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. Laptook AR, et al. JAMA. 2017 Oct 24;318(16):1550-1560. doi: 10.1001/jama.2017.14972. JAMA. 2017. PMID: 29067428 Free PMC article. Clinical Trial.
IMPORTANCE: Hypothermia initiated at less than 6 hours after birth reduces death or disability for infants with hypoxic-ischemic encephalopathy at 36 weeks' or later gestation. ...Hypothermia initiated at 6 to 24 hours after birth may have benefit but there is uncer …
IMPORTANCE: Hypothermia initiated at less than 6 hours after birth reduces death or disability for infants with hypoxic-ischemic ence …
Conference summary: What we have learned and where we are headed.
Maslen CL. Maslen CL. Am J Med Genet C Semin Med Genet. 2019 Mar;181(1):25-27. doi: 10.1002/ajmg.c.31669. Epub 2019 Jan 11. Am J Med Genet C Semin Med Genet. 2019. PMID: 30633444 Review.
This overview highlights the actionable near-term objectives for the TRN drawn from discussions in the breakout sessions. ...
This overview highlights the actionable near-term objectives for the TRN drawn from discussions in the breakout sessions. ...
The Use of SGLT-2 Inhibitors in Type 2 Diabetes and Heart Failure.
Riggs K, Ali H, Taegtmeyer H, Gutierrez AD. Riggs K, et al. Metab Syndr Relat Disord. 2015 Sep;13(7):292-7. doi: 10.1089/met.2015.0038. Epub 2015 Jun 30. Metab Syndr Relat Disord. 2015. PMID: 26125313 Free PMC article. Review.
Based on the available evidence, SGLT-2 inhibitors are safe and can be recommended to treat T2DM in patients with chronic heart failure and intact renal function. Further studies are in progress to assess long-term survival benefits....
Based on the available evidence, SGLT-2 inhibitors are safe and can be recommended to treat T2DM in patients with chronic heart failure and …
A unified mediation analysis framework for integrative cancer proteogenomics with clinical outcomes.
Huang L, Long JP, Irajizad E, Doecke JD, Do KA, Ha MJ. Huang L, et al. Bioinformatics. 2023 Jan 1;39(1):btad023. doi: 10.1093/bioinformatics/btad023. Bioinformatics. 2023. PMID: 36648331 Free PMC article.
Using kidney renal clear cell carcinoma proteogenomic data, we identify genes that are mediated by proteins and the underlying mechanisms on various survival outcomes that capture short- and long-term disease-specific clinical characteristics. AVAILABILITY AND IMPLEMENTATI …
Using kidney renal clear cell carcinoma proteogenomic data, we identify genes that are mediated by proteins and the underlying mechanisms on …
Propranolol and Mesenchymal Stromal Cells Combine to Treat Traumatic Brain Injury.
Kota DJ, Prabhakara KS, van Brummen AJ, Bedi S, Xue H, DiCarlo B, Cox CS Jr, Olson SD. Kota DJ, et al. Stem Cells Transl Med. 2016 Jan;5(1):33-44. doi: 10.5966/sctm.2015-0065. Epub 2015 Nov 19. Stem Cells Transl Med. 2016. PMID: 26586775 Free PMC article.
MSCs decrease BBB permeability at 96 hours after injury, inhibit a significant accumulation of activated microglia/macrophage in the thalamic region of the brain both short and long term, and enhance neurogenesis short term. Propranolol decreases edema and reduces t …
MSCs decrease BBB permeability at 96 hours after injury, inhibit a significant accumulation of activated microglia/macrophage in the thalami …
65 results