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GDAP1 loss of function inhibits the mitochondrial pyruvate dehydrogenase complex by altering the actin cytoskeleton.
Wolf C, Pouya A, Bitar S, Pfeiffer A, Bueno D, Rojas-Charry L, Arndt S, Gomez-Zepeda D, Tenzer S, Bello FD, Vianello C, Ritz S, Schwirz J, Dobrindt K, Peitz M, Hanschmann EM, Mencke P, Boussaad I, Silies M, Brüstle O, Giacomello M, Krüger R, Methner A. Wolf C, et al. Commun Biol. 2022 Jun 3;5(1):541. doi: 10.1038/s42003-022-03487-6. Commun Biol. 2022. PMID: 35662277 Free PMC article.
GDAP1 interacts with the actin-depolymerizing protein Cofilin-1 and beta-tubulin in a redox-dependent manner, suggesting a role for actin signaling. Consistently, GDAP1 loss causes less F-actin close to mitochondria, which restricts mitochondrial localization of the fissio …
GDAP1 interacts with the actin-depolymerizing protein Cofilin-1 and beta-tubulin in a redox-dependent manner, suggesting a role for actin si …
SARS-CoV-2 mRNA-vaccine candidate; COReNAPCIN®, induces robust humoral and cellular immunity in mice and non-human primates.
Alimohammadi R, Porgoo M, Eftekhary M, Kiaie SH, Ansari Dezfouli E, Dehghani M, Nasrollahi K, Malekshahabi T, Heidari M, Pouya S, Alimohammadi M, Sattari Khavas D, Modaresi MS, Ghasemi MH, Ramyar H, Mohammadipour F, Hamzelouei F, Mofayezi A, Mottaghi SS, Rahmati A, Razzaznian M, Tirandazi V, Tat M, Borzouee F, Sadeghi H, Haji Mohammadi M, Rastegar L, Safar Sajadi SM, Ehsanbakhsh H, Bazmbar H, Baghernejadan Z, Shams Nouraei M, Pazooki P, Pahlavanneshan M, Alishah K, Nasiri F, Mokhberian N, Mohammadi SS, Akar S, Niknam H, Azizi M, Ajoudanian M, Moteallehi-Ardakani MH, Mousavi Shaegh SA, Ramezani R, Salimi V, Moazzami R, Hashemi SM, Dehghanizadeh S, Khoddami V. Alimohammadi R, et al. NPJ Vaccines. 2022 Sep 2;7(1):105. doi: 10.1038/s41541-022-00528-3. NPJ Vaccines. 2022. PMID: 36056015 Free PMC article.
Assessment of Transmural Dispersion of Repolarization in Children with Mitral Valve Prolapse.
Ghandi Y, Ghahremani B, Habibi D, Pouya A, Sadrnia S. Ghandi Y, et al. J Tehran Heart Cent. 2020 Apr;15(2):64-68. doi: 10.18502/jthc.v15i2.4185. J Tehran Heart Cent. 2020. PMID: 33552196 Free PMC article.
Results: The mean age of the 50 patients with MVP was 12.452.50 years (F/M: 15/35). There were no significant differences in QT and QTc intervals between the 2 groups. ...
Results: The mean age of the 50 patients with MVP was 12.452.50 years (F/M: 15/35). There were no significant differences in QT and Q …