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Page 1
Complement blockade with eculizumab for treatment of severe Coronavirus Disease 2019 in pregnancy: A case series.
Burwick RM, Dellapiana G, Newman RA, Smithson SD, Naqvi M, Williams J 3rd, Wong MS, Bautista M, Gaden A, Kazani SD, Dunn DA, Ma MH, Mitter S, Monteleone JPR, Ortiz SR, Ghandehari S, Merin N, Zakowski MI, Karumanchi SA. Burwick RM, et al. Am J Reprod Immunol. 2022 Aug;88(2):e13559. doi: 10.1111/aji.13559. Epub 2022 May 12. Am J Reprod Immunol. 2022. PMID: 35514201 Free PMC article. Clinical Trial.
Silk-Elastinlike Protein Polymer Liquid Chemoembolic for Localized Release of Doxorubicin and Sorafenib.
Poursaid A, Jensen MM, Nourbakhsh I, Weisenberger M, Hellgeth JW, Sampath S, Cappello J, Ghandehari H. Poursaid A, et al. Mol Pharm. 2016 Aug 1;13(8):2736-48. doi: 10.1021/acs.molpharmaceut.6b00325. Epub 2016 Jun 29. Mol Pharm. 2016. PMID: 27295352
In this work, two chemotherapeutics used in the treatment of HCC, doxorubicin and sorafenib, were incorporated into the in situ gelling liquid embolic composed of a silk-elastinlike protein polymer (SELP-815 K). The base forms of the drugs had no significant effect on the …
In this work, two chemotherapeutics used in the treatment of HCC, doxorubicin and sorafenib, were incorporated into the in situ gelling liqu …
Novel lytic bacteriophages of Klebsiella oxytoca ABG-IAUF-1 as the potential agents for mastitis phage therapy.
Amiri Fahliyani S, Beheshti-Maal K, Ghandehari F. Amiri Fahliyani S, et al. FEMS Microbiol Lett. 2018 Oct 1;365(20). doi: 10.1093/femsle/fny223. FEMS Microbiol Lett. 2018. PMID: 30212876
In this study Klebsiella oxytoca was isolated from contaminated milk samples of Isfahan dairy herds, Isfahan, Iran and characterized as K. oxytoca ABG-IAUF-1 and its 16s-rRNA sequence was deposited in GenBank under the accession numbers of MF175803.1. Then, the four novel …
In this study Klebsiella oxytoca was isolated from contaminated milk samples of Isfahan dairy herds, Isfahan, Iran and characterized as K …
In vitro chondrogenesis of mesenchymal stem cells in recombinant silk-elastinlike hydrogels.
Haider M, Cappello J, Ghandehari H, Leong KW. Haider M, et al. Pharm Res. 2008 Mar;25(3):692-9. doi: 10.1007/s11095-007-9282-8. Epub 2007 Apr 3. Pharm Res. 2008. PMID: 17404809 Free PMC article.
PURPOSE: In this study the chondrocytic differentiation and cartilage matrix accumulation of human mesenchymal stem cells (hMSCs) were investigated after encapsulation in a genetically engineered silk-elastinlike protein polymer SELP-47 K as an injectable matrix for delive …
PURPOSE: In this study the chondrocytic differentiation and cartilage matrix accumulation of human mesenchymal stem cells (hMSCs) were inves …
COMPARATIVE PHARMACOKINETICS OF PAMAM-OH DENDRIMERS AND HPMA COPOLYMERS IN OVARIAN-TUMOR-BEARING MICE.
Sadekar S, Linares O, Noh G, Hubbard D, Ray A, Janát-Amsbury M, Peterson CM, Facelli J, Ghandehari H. Sadekar S, et al. Drug Deliv Transl Res. 2013 Jun 1;3(3):260-271. doi: 10.1007/s13346-012-0119-6. Drug Deliv Transl Res. 2013. PMID: 23795337 Free PMC article.
A plasma-tumor link model was fitted to experimental plasma and tumor data by varying the tumor extravasation (K(4), K(6)) and elimination (K(5)) rate constants using multivariable constrained optimization solver in Matlab. ...
A plasma-tumor link model was fitted to experimental plasma and tumor data by varying the tumor extravasation (K(4), K(6)) and …
Silk-elastinlike recombinant polymers for gene therapy of head and neck cancer: from molecular definition to controlled gene expression.
Gustafson J, Greish K, Frandsen J, Cappello J, Ghandehari H. Gustafson J, et al. J Control Release. 2009 Dec 16;140(3):256-61. doi: 10.1016/j.jconrel.2009.05.022. Epub 2009 May 24. J Control Release. 2009. PMID: 19470397 Free PMC article.
SELP-815K, with eight silk and fifteen elastin units and a lysine (K) modified elastin, was compared to SELP-415K and SELP-47K. Hydrogels with higher silk content and concentration degraded at a slower rate compared to other analogs. ...
SELP-815K, with eight silk and fifteen elastin units and a lysine (K) modified elastin, was compared to SELP-415K and SELP-47K. Hydro …
Recombinant polymer-protein fusion: a promising approach towards efficient and targeted gene delivery.
Hatefi A, Megeed Z, Ghandehari H. Hatefi A, et al. J Gene Med. 2006 Apr;8(4):468-76. doi: 10.1002/jgm.872. J Gene Med. 2006. PMID: 16416505
The carrier was designed to have the structure of (KHKHKHKHKK)6-FGF2 where lysine (K) residues would allow complexation with plasmid DNA, basic fibroblast growth factor (FGF2) to target cells over-expressing FGF2 receptors (FGFR), and histidine (H) residues to facilitate e …
The carrier was designed to have the structure of (KHKHKHKHKK)6-FGF2 where lysine (K) residues would allow complexation with plasmid …
Photoelectron spectra of some important biological molecules: symmetry-adapted-cluster configuration interaction study.
Farrokhpour H, Ghandehari M. Farrokhpour H, et al. J Phys Chem B. 2013 May 23;117(20):6027-41. doi: 10.1021/jp311213c. Epub 2013 May 9. J Phys Chem B. 2013. PMID: 23659524
The calculated first ionization energies of the considered molecules were correlated with their Huckel k-index to obtain Coulomb (alpha) and resonance (beta) integrals of the Huckel molecular orbital theory for the biomolecules considered in this study. A linear correlatio …
The calculated first ionization energies of the considered molecules were correlated with their Huckel k-index to obtain Coulomb (alp …