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Investigation of the interaction between berberine and nucleosomes in solution: Spectroscopic and equilibrium dialysis approach.
Rabbani-Chadegani A, Mollaei H, Sargolzaei J. Rabbani-Chadegani A, et al. Spectrochim Acta A Mol Biomol Spectrosc. 2017 Feb 15;173:418-424. doi: 10.1016/j.saa.2016.09.052. Epub 2016 Sep 28. Spectrochim Acta A Mol Biomol Spectrosc. 2017. PMID: 27705846
The results showed that the binding of berberine to nucleosomes is positive cooperative with Ka=5.5710(3)M(-1). Berberine quenched with the chromophores of protein moiety of nucleosomes and reduced fluorescence emission intensity at 335nm with Ksv value of 0.135. ...Berber …
The results showed that the binding of berberine to nucleosomes is positive cooperative with Ka=5.5710(3)M(-1). Berberine quenched wi …