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SARS-CoV-2 structural features may explain limited neutralizing-antibody responses.
Bachmann MF, Mohsen MO, Zha L, Vogel M, Speiser DE. Bachmann MF, et al. NPJ Vaccines. 2021 Jan 4;6(1):2. doi: 10.1038/s41541-020-00264-6. NPJ Vaccines. 2021. PMID: 33398006 Free PMC article.
Therefore, the neutralizing epitopes (which are on the S protein) are loosely "floating" and widely spaced by an average of about 25 nm. Consequently, recruitment of complement is poor and stimulation of B cells remains suboptimal, offering an explanation for the in …
Therefore, the neutralizing epitopes (which are on the S protein) are loosely "floating" and widely spaced by an average of about 25 nm. Con …
Interferon-α alters host glycosylation machinery during treated HIV infection.
Giron LB, Colomb F, Papasavvas E, Azzoni L, Yin X, Fair M, Anzurez A, Damra M, Mounzer K, Kostman JR, Tebas P, O'Doherty U, Tateno H, Liu Q, Betts MR, Montaner LJ, Abdel-Mohsen M. Giron LB, et al. EBioMedicine. 2020 Sep;59:102945. doi: 10.1016/j.ebiom.2020.102945. Epub 2020 Aug 19. EBioMedicine. 2020. PMID: 32827942 Free PMC article.
FINDINGS: We identified significant interactions that support a model in which a) IFNalpha increases the proportion of pro-inflammatory, bisecting GlcNAc glycans (known to enhance FcgammaR binding) within the IgG glycome, which in turn b) increases inflammation, which c) l …
FINDINGS: We identified significant interactions that support a model in which a) IFNalpha increases the proportion of pro-inflammatory, bis …
Parent's food literacy and adolescents nutrition literacy influence household's food security and adolescent's malnutrition and anemia: Findings from a national representative cross sectional study.
Hoteit M, Mohsen H, Hanna-Wakim L, Sacre Y. Hoteit M, et al. Front Nutr. 2022 Dec 30;9:1053552. doi: 10.3389/fnut.2022.1053552. eCollection 2022. Front Nutr. 2022. PMID: 36643976 Free PMC article.
RESULTS: Around 45.0% of the adolescents were nutritionally illiterate, and nearly half (47.8%) of parents had poor FL. Around 68.2 and 54.0% of the households and adolescents were food insecure, respectively. Moreover, 6.7, 4.7, 32.2, and 16.7% of the adolescents were stu …
RESULTS: Around 45.0% of the adolescents were nutritionally illiterate, and nearly half (47.8%) of parents had poor FL. Around 68.2 a …
Association between matrix metalloproteinase 2 (MMP2) promoter polymorphisms and the susceptibility to non-Hodgkin's lymphoma in Egyptians.
Gouda HM, Khorshied MM, El Sissy MH, Shaheen IA, Mohsen MM. Gouda HM, et al. Ann Hematol. 2014 Aug;93(8):1313-8. doi: 10.1007/s00277-014-2054-8. Epub 2014 Mar 14. Ann Hematol. 2014. PMID: 24627195
The polymorphic allele, T allele, conferred almost fourfold increased risk of B-NHL (OR = 3.8, 95 %CI = 1.05-13.9), and the risk elevated to be almost eight folds when confined to diffuse large B-cell lymphoma (DLBCL) (OR = 7.9, 95 %CI = 1.67-32.27). ...In conclusio …
The polymorphic allele, T allele, conferred almost fourfold increased risk of B-NHL (OR = 3.8, 95 %CI = 1.05-13.9), and the risk elev …
Early and long term anamnestic response to HBV booster dose among fully vaccinated Egyptian children during infancy.
Salama II, Sami SM, Said ZN, Salama SI, Rabah TM, Abdel-Latif GA, Elmosalami DM, Saleh RM, Abdel Mohsin AM, Metwally AM, Hassanin AI, Emam HM, Hemida SA, Elserougy SM, Shaaban FA, Fouad WA, Mohsen A, El-Sayed MH. Salama II, et al. Vaccine. 2018 Apr 5;36(15):2005-2011. doi: 10.1016/j.vaccine.2018.02.103. Epub 2018 Mar 9. Vaccine. 2018. PMID: 29530634
After one year, long term anamnestic response was absent among 15% of children who previously showed early response. Poor early anamnestic response and undetectable pre-booster anti-HBs were the significant predicting risk factors for absent long term anamnestic response, …
After one year, long term anamnestic response was absent among 15% of children who previously showed early response. Poor early anamn …
Sorafenib in the treatment of hepatocellular carcinoma: a multi-centre real-world study.
Doyle A, Marsh P, Gill R, Rodov M, Mohsen W, Varma P, Hong T, Strasser SI, Bell S, Ryan M, Nicoll A, Lubel J, Gow PJ, Fink MA, Roberts S, Kemp W, Kronborg I, Arachchi N, Knight V, Dev A. Doyle A, et al. Scand J Gastroenterol. 2016 Aug;51(8):979-85. doi: 10.3109/00365521.2016.1166518. Epub 2016 May 10. Scand J Gastroenterol. 2016. PMID: 27161568
CONCLUSIONS: Survival in patients with Child-Pugh C liver function or advanced functional impairment treated with sorafenib is poor and thus routine use of this agent in these patients does not appear justified, particularly given the high rate of adverse effects. ...
CONCLUSIONS: Survival in patients with Child-Pugh C liver function or advanced functional impairment treated with sorafenib is poor a …