Therapeutic avenues in bone repair: Harnessing an anabolic osteopeptide, PEPITEM, to boost bone growth and prevent bone loss.
Lewis JW, Frost K, Neag G, Wahid M, Finlay M, Northall EH, Abudu O, Davis ET, Powell E, Palmer C, Lu J, Rainger GE, Iqbal AJ, Chimen M, Mahmood A, Jones SW, Edwards JR, Naylor AJ, McGettrick HM.
Lewis JW, et al.
Cell Rep Med. 2024 May 21;5(5):101574. doi: 10.1016/j.xcrm.2024.101574.
Cell Rep Med. 2024.
PMID: 38776873
The existing suite of therapies for bone diseases largely act to prevent further bone loss but fail to stimulate healthy bone formation and repair. We describe an endogenous osteopeptide (PEPITEM) with anabolic osteogenic activity, regulating bone remodeling in h …
The existing suite of therapies for bone diseases largely act to prevent further bone loss but fail to stimulate healthy bone formati …