Bruton Tyrosine Kinase in Lesions of Multiple Sclerosis and 3 of Its Models.
Li C, Morch MT, Gorter R, Lozinski B, Ghorbani S, Dong Y, Shen YA, Harp C, Zandee S, Klement W, Prat A, Yong VW.
Li C, et al.
Neurol Neuroimmunol Neuroinflamm. 2025 Jul;12(4):e200413. doi: 10.1212/NXI.0000000000200413. Epub 2025 May 29.
Neurol Neuroimmunol Neuroinflamm. 2025.
PMID: 40440578
Free PMC article.
BACKGROUND AND OBJECTIVES: The pathophysiology of multiple sclerosis (MS) is contributed by B lymphocytes, macrophages, and microglia. Bruton tyrosine kinase (BTK) is an intracellular enzyme within these cells that modulates their inflammatory properties. ...
BACKGROUND AND OBJECTIVES: The pathophysiology of multiple sclerosis (MS) is contributed by B lymphocytes, macrophages, and microglia …