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Page 1
Safety and Efficacy of NVX-CoV2373 Covid-19 Vaccine.
Heath PT, Galiza EP, Baxter DN, Boffito M, Browne D, Burns F, Chadwick DR, Clark R, Cosgrove C, Galloway J, Goodman AL, Heer A, Higham A, Iyengar S, Jamal A, Jeanes C, Kalra PA, Kyriakidou C, McAuley DF, Meyrick A, Minassian AM, Minton J, Moore P, Munsoor I, Nicholls H, Osanlou O, Packham J, Pretswell CH, San Francisco Ramos A, Saralaya D, Sheridan RP, Smith R, Soiza RL, Swift PA, Thomson EC, Turner J, Viljoen ME, Albert G, Cho I, Dubovsky F, Glenn G, Rivers J, Robertson A, Smith K, Toback S; 2019nCoV-302 Study Group. Heath PT, et al. N Engl J Med. 2021 Sep 23;385(13):1172-1183. doi: 10.1056/NEJMoa2107659. Epub 2021 Jun 30. N Engl J Med. 2021. PMID: 34192426 Free PMC article. Clinical Trial.
A post hoc analysis showed an efficacy of 86.3% (95% CI, 71.3 to 93.5) against the B.1.1.7 (or alpha) variant and 96.4% (95% CI, 73.8 to 99.5) against non-B.1.1.7 variants. ...CONCLUSIONS: A two-dose regimen of the NVX-CoV2373 vaccine administered to adult participa …
A post hoc analysis showed an efficacy of 86.3% (95% CI, 71.3 to 93.5) against the B.1.1.7 (or alpha) variant and 96.4% (95% CI, 73.8 …
Preparation, characterization, and evaluation of eosin B-loaded nano-liposomes for growth inhibition of Plasmodium falciparum.
Najafzadeh M, Bakhshandeh H, Zamani Z, Movahedi M, Atyabi SM. Najafzadeh M, et al. Parasitol Res. 2022 Jan;121(1):383-393. doi: 10.1007/s00436-021-07395-2. Epub 2022 Jan 6. Parasitol Res. 2022. PMID: 34993631
Finally, the eosin B-loaded liposomes were tested on Plasmodium falciparum in culture to evaluate its anti-plasmodial effect. ...The results indicate a greater effect of liposomal-formulated eosin B on inhibiting parasite growth compared to the free eosin B.. …
Finally, the eosin B-loaded liposomes were tested on Plasmodium falciparum in culture to evaluate its anti-plasmodial effect. ...The …
Biallelic human SHARPIN loss of function induces autoinflammation and immunodeficiency.
Oda H, Manthiram K, Chavan PP, Rieser E, Veli Ö, Kaya Ö, Rauch C, Nakabo S, Kuehn HS, Swart M, Wang Y, Çelik NI, Molitor A, Ziaee V, Movahedi N, Shahrooei M, Parvaneh N, Alipour-Olyei N, Carapito R, Xu Q, Preite S, Beck DB, Chae JJ, Nehrebecky M, Ombrello AK, Hoffmann P, Romeo T, Deuitch NT, Matthíasardóttir B, Mullikin J, Komarow H, Stoddard J, Niemela J, Dobbs K, Sweeney CL, Anderton H, Lawlor KE, Yoshitomi H, Yang D, Boehm M, Davis J, Mudd P, Randazzo D, Tsai WL, Gadina M, Kaplan MJ, Toguchida J, Mayer CT, Rosenzweig SD, Notarangelo LD, Iwai K, Silke J, Schwartzberg PL, Boisson B, Casanova JL, Bahram S, Rao AP, Peltzer N, Walczak H, Lalaoui N, Aksentijevich I, Kastner DL. Oda H, et al. Nat Immunol. 2024 May;25(5):764-777. doi: 10.1038/s41590-024-01817-w. Epub 2024 Apr 12. Nat Immunol. 2024. PMID: 38609546
Here, we report two individuals with SHARPIN deficiency who manifest autoinflammatory symptoms but unexpectedly no dermatological problems. Fibroblasts and B cells from these individuals showed attenuated canonical NF-kappaB responses and a propensity for cell death mediat …
Here, we report two individuals with SHARPIN deficiency who manifest autoinflammatory symptoms but unexpectedly no dermatological problems. …
Liver transplant: a primer.
Movahedi Z, Holt CD, Saab S. Movahedi Z, et al. Exp Clin Transplant. 2010 Jun;8(2):83-90. Exp Clin Transplant. 2010. PMID: 20565363 Free article. Review.
Immunosuppressive regimen pharmacologic classes include calcineurin inhibitors, antimetabolites, mTOR inhibitors, steroids, and antibody-based therapies. These agents affect T-cell-dependent B-cell activation, and target different sites in the T-cell activation cascade by …
Immunosuppressive regimen pharmacologic classes include calcineurin inhibitors, antimetabolites, mTOR inhibitors, steroids, and antibody-bas …
Altered pattern of Naive and memory B cells and B1 cells in patients with chronic granulomatous disease.
Mohsenzadegan M, Fattahi F, Fattahi F, Mirshafiey A, Fazlollahi MR, Naderi Beni F, Movahedi M, Pourpak Z. Mohsenzadegan M, et al. Iran J Allergy Asthma Immunol. 2014 Jun;13(3):157-65. Iran J Allergy Asthma Immunol. 2014. PMID: 24659119 Free article.
We found significantly higher levels of naive B cells and B1a cells but lower levels of memory B cells in CGD patients compared to HC.. ...Our findings suggested a role for NADPH oxidase in process of B cell differentiation and impairing conversion of naive …
We found significantly higher levels of naive B cells and B1a cells but lower levels of memory B cells in CGD patients compare …
Characteristics and molecular identification of glyceraldehyde-3-phosphate dehydrogenases in poplar.
Wei H, Movahedi A, Yang J, Zhang Y, Liu G, Zhu S, Yu C, Chen Y, Zhong F, Zhang J. Wei H, et al. Int J Biol Macromol. 2022 Oct 31;219:185-198. doi: 10.1016/j.ijbiomac.2022.08.001. Epub 2022 Aug 3. Int J Biol Macromol. 2022. PMID: 35932802
Phylogenetic tree showed that the PtGAPDH members were divided into PtGAPA/B, PtGAPC, PtGAPCp, and PtGAPN groups. A total of 13 PtGAPDH genes were distributed on eight chromosomes, 13 gene pairs belonging to segmented replication events were detected in poplar, and 23 coll …
Phylogenetic tree showed that the PtGAPDH members were divided into PtGAPA/B, PtGAPC, PtGAPCp, and PtGAPN groups. A total of 13 PtGAP …
Endothelial C-Type Natriuretic Peptide Acts on Pericytes to Regulate Microcirculatory Flow and Blood Pressure.
Špiranec K, Chen W, Werner F, Nikolaev VO, Naruke T, Koch F, Werner A, Eder-Negrin P, Diéguez-Hurtado R, Adams RH, Baba HA, Schmidt H, Schuh K, Skryabin BV, Movahedi K, Schweda F, Kuhn M. Špiranec K, et al. Circulation. 2018 Jul 31;138(5):494-508. doi: 10.1161/CIRCULATIONAHA.117.033383. Circulation. 2018. PMID: 29626067
Mice with a floxed GC-B ( Npr2) gene were interbred with Tie2-Cre or PDGF-Rbeta-Cre (ERT2) lines to develop mice lacking GC-B in endothelial cells or in precapillary arteriolar SMCs and capillary pericytes. ...It is notable that the vasodilatatory effects of CNP wer …
Mice with a floxed GC-B ( Npr2) gene were interbred with Tie2-Cre or PDGF-Rbeta-Cre (ERT2) lines to develop mice lacking GC-B …
Lymphoma of mucosa-associated lymphoid tissue in common variable immunodeficiency.
Aghamohammadi A, Parvaneh N, Tirgari F, Mahjoob F, Movahedi M, Gharagozlou M, Mansouri M, Kouhi A, Rezaei N, Webster D. Aghamohammadi A, et al. Leuk Lymphoma. 2006 Feb;47(2):343-6. doi: 10.1080/10428190500285285. Leuk Lymphoma. 2006. PMID: 16321869 Review.
Mucosa-associated lymphoid tissue (MALT) lymphomas are a recently recognized sub-set of low-grade B-cell NHL composed of marginal zone-related cells. MALT lymphomas appear in the lymphoid tissues as a result of chronic inflammatory or autoimmune stimulation. ...Open lung b …
Mucosa-associated lymphoid tissue (MALT) lymphomas are a recently recognized sub-set of low-grade B-cell NHL composed of marginal zon …
Statin Use for Primary Cardiovascular Disease Prevention Is Low in Inflammatory Arthritis.
Kuriya B, Akhtari S, Movahedi M, Udell JA, Lawler PR, Farkouh ME, Keystone EC, Hanneman K, Nguyen E, Harvey PJ, Eder L. Kuriya B, et al. Can J Cardiol. 2022 Aug;38(8):1244-1252. doi: 10.1016/j.cjca.2022.04.002. Epub 2022 Apr 13. Can J Cardiol. 2022. PMID: 35429590
The majority was low FRS risk category (68%), and the most frequent qualifier for statins was elevated apolipoprotein B (ApoB) levels or low-density lipoprotein cholesterol (LDL-c) levels. ...
The majority was low FRS risk category (68%), and the most frequent qualifier for statins was elevated apolipoprotein B (ApoB) levels …
Comparative analysis of antibody- and lipid-based multiplexing methods for single-cell RNA-seq.
Mylka V, Matetovici I, Poovathingal S, Aerts J, Vandamme N, Seurinck R, Verstaen K, Hulselmans G, Van den Hoecke S, Scheyltjens I, Movahedi K, Wils H, Reumers J, Van Houdt J, Aerts S, Saeys Y. Mylka V, et al. Genome Biol. 2022 Feb 16;23(1):55. doi: 10.1186/s13059-022-02628-8. Genome Biol. 2022. PMID: 35172874 Free PMC article.
RESULTS: Here, we compare the hashing performance of TotalSeq-A and -C antibodies, custom synthesized lipids and MULTI-seq lipid hashes in four cell lines, both for single-cell RNA-seq and single-nucleus RNA-seq. We also compare TotalSeq-B antibodies with CellPlex reagents …
RESULTS: Here, we compare the hashing performance of TotalSeq-A and -C antibodies, custom synthesized lipids and MULTI-seq lipid hashes in f …
71 results