Regulatory roles of IL-10-producing human follicular T cells.
Cañete PF, Sweet RA, Gonzalez-Figueroa P, Papa I, Ohkura N, Bolton H, Roco JA, Cuenca M, Bassett KJ, Sayin I, Barry E, Lopez A, Canaday DH, Meyer-Hermann M, Doglioni C, Fazekas de St Groth B, Sakaguchi S, Cook MC, Vinuesa CG.
Cañete PF, et al. Among authors: sayin i.
J Exp Med. 2019 Aug 5;216(8):1843-1856. doi: 10.1084/jem.20190493. Epub 2019 Jun 17.
J Exp Med. 2019.
PMID: 31209070
Free PMC article.
Despite lack of FOXP3 expression, CD25(+) T(F) cells resemble T reg cells in high CTLA4 expression, low IL-2 production, and their ability to repress T cell proliferation. CD25(+) T(F) cell-derived IL-10 dampens induction of B cell class-switching to IgE. In children, circ …
Despite lack of FOXP3 expression, CD25(+) T(F) cells resemble T reg cells in high CTLA4 expression, low IL-2 production, and their ability t …