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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1944 1
1949 1
1962 1
1967 1
1971 1
1972 1
1973 1
1974 1
1975 2
1976 3
1977 5
1978 7
1979 4
1980 10
1981 10
1982 10
1983 14
1984 11
1985 11
1986 20
1987 22
1988 16
1989 42
1990 61
1991 66
1992 66
1993 76
1994 108
1995 108
1996 113
1997 116
1998 140
1999 142
2000 192
2001 184
2002 233
2003 277
2004 365
2005 465
2006 483
2007 616
2008 667
2009 701
2010 847
2011 881
2012 1016
2013 1139
2014 1316
2015 1535
2016 1634
2017 1710
2018 2020
2019 2212
2020 2346
2021 2360
2022 2495
2023 2338
2024 1212

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27,118 results

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Page 1
Electrophotocatalytic diamination of vicinal C-H bonds.
Shen T, Lambert TH. Shen T, et al. Science. 2021 Feb 5;371(6529):620-626. doi: 10.1126/science.abf2798. Epub 2021 Feb 4. Science. 2021. PMID: 33542135 Free PMC article.
The conversion of unactivated carbon-hydrogen (C-H) bonds to carbon-nitrogen (C-N) bonds is a highly valued transformation. Existing strategies typically accomplish such reactions at only a single C-H site because the first derivatization diminishes the react …
The conversion of unactivated carbon-hydrogen (C-H) bonds to carbon-nitrogen (C-N) bonds is a highly valued transformation. Ex …
C-H Amination via Electrophotocatalytic Ritter-type Reaction.
Shen T, Lambert TH. Shen T, et al. J Am Chem Soc. 2021 Jun 16;143(23):8597-8602. doi: 10.1021/jacs.1c03718. Epub 2021 Jun 2. J Am Chem Soc. 2021. PMID: 34076424 Free PMC article.
A method for C-H bond amination via an electrophotocatalytic Ritter-type reaction is described. The reaction is catalyzed by a trisaminocyclopropenium (TAC) ion in an electrochemical cell under irradiation. These conditions convert benzylic C-H bonds to acetamides w …
A method for C-H bond amination via an electrophotocatalytic Ritter-type reaction is described. The reaction is catalyzed by a trisam …
Shen Shuai II Recipe Attenuates Renal Interstitial Fibrosis by Improving Hypoxia via the IL-1beta/c-Myc Pathway.
Yang L, Wang M, Zhou Y, Yang J, Ye C, Wang C. Yang L, et al. Evid Based Complement Alternat Med. 2021 Jun 7;2021:5539584. doi: 10.1155/2021/5539584. eCollection 2021. Evid Based Complement Alternat Med. 2021. PMID: 34211565 Free PMC article.
Furthermore, we also studied the changes in protein expression of c-Myc and fibrosis-related factors after c-Myc gene silencing in IL-1beta-stimulated NRK-49F treated with SSR. RESULTS: Shen Shuai II Recipe significantly reduced RIF and downregulated the expr …
Furthermore, we also studied the changes in protein expression of c-Myc and fibrosis-related factors after c-Myc gene silencin …
Neuronal polarity in C. elegans.
Ou CY, Shen K. Ou CY, et al. Dev Neurobiol. 2011 Jun;71(6):554-66. doi: 10.1002/dneu.20858. Dev Neurobiol. 2011. PMID: 21557505 Review.
The simplicity and availability of practical genetic tools makes C. elegans as an ideal model to study neuronal polarity in vivo. In recent years, new studies have identified critical polarity molecules that function at different stages of neuronal polarization in C …
The simplicity and availability of practical genetic tools makes C. elegans as an ideal model to study neuronal polarity in vivo. In …
C-C Bond Cleavage Initiated Cascade Reaction of beta-Enaminones: One-Pot Synthesis of 5-Hydroxy-1H-pyrrol-2(5H)-ones.
Chen T, Zheng X, Wang W, Feng Y, Wang Y, Shen J. Chen T, et al. J Org Chem. 2021 Feb 5;86(3):2917-2928. doi: 10.1021/acs.joc.0c02832. Epub 2021 Jan 13. J Org Chem. 2021. PMID: 33439021
An unprecedented C(CO)-C(Ar) bond cleavage of beta-enaminones has been realized under mild and transition-metal-free conditions. The cascade transformation based on this C-C bond cleavage involves 1,3-O/C migration and aerobic hydroxylation and …
An unprecedented C(CO)-C(Ar) bond cleavage of beta-enaminones has been realized under mild and transition-metal-free condition …
11α,15α-Dihy-droxy-androst-4-ene-3,17-dione.
Shen YB, Wang M, Liang QK, Luo JM. Shen YB, et al. Acta Crystallogr Sect E Struct Rep Online. 2011 Oct 1;67(Pt 10):o2752. doi: 10.1107/S1600536811038608. Epub 2011 Sep 30. Acta Crystallogr Sect E Struct Rep Online. 2011. PMID: 22058810 Free PMC article.
The title compound, C(19)H(26)O(4), was biotransformed from androstenedione. In the crystal, inter-molecular O-HO hydrogen bonds link molecules into a corrugated sheet, which lies parallel to the ab plane. Ring A has a slightly distorted half-chair conformation, rings B an …
The title compound, C(19)H(26)O(4), was biotransformed from androstenedione. In the crystal, inter-molecular O-HO hydrogen bonds link …
Electrochemical Aerobic Oxidative Cleavage of (sp(3))C-C(sp(3))/H Bonds in Alkylarenes.
Shen T, Liu S, Zhao J, Wang N, Yang L, Wu J, Shen X, Liu ZQ. Shen T, et al. J Org Chem. 2022 Mar 4;87(5):3286-3295. doi: 10.1021/acs.joc.1c02947. Epub 2022 Feb 21. J Org Chem. 2022. PMID: 35188765
An electrochemistry-promoted oxidative cleavage of (sp(3))C-C(sp(3))/H bonds in alkylarenes was developed. Various aryl alkanes can be smoothly converted into ketones/aldehydes under aerobic conditions using a user-friendly undivided cell setup. ...
An electrochemistry-promoted oxidative cleavage of (sp(3))C-C(sp(3))/H bonds in alkylarenes was developed. Various aryl alkane …
Bis(2,9-dimethyl-1,10-phenanthroline-κN,N')bis-(nitrato-κO,O')lead(II).
Shen FM, Lush SF. Shen FM, et al. Acta Crystallogr Sect E Struct Rep Online. 2010 Jun 16;66(Pt 7):m805-6. doi: 10.1107/S1600536810022312. Acta Crystallogr Sect E Struct Rep Online. 2010. PMID: 21587725 Free PMC article.
In the title complex, [Pb(NO(3))(2)(C(14)H(12)N(2))(2)], the lead ion is chelated by two 2,9-dimethyl-1,10-phenanthroline (dmphen) ligands and two nitrate anions in a slightly distorted square-anti-prismatic geometry. Intra- and inter-molecular pi-pi stacking is present in …
In the title complex, [Pb(NO(3))(2)(C(14)H(12)N(2))(2)], the lead ion is chelated by two 2,9-dimethyl-1,10-phenanthroline (dmphen) li …
7-Fluoro-6-nitro-quinazolin-4(3H)-one.
Wu Y, Ji A, Zhang A, Shen Y. Wu Y, et al. Acta Crystallogr Sect E Struct Rep Online. 2009 Nov 14;65(Pt 12):o3075. doi: 10.1107/S1600536809046984. Acta Crystallogr Sect E Struct Rep Online. 2009. PMID: 21578805 Free PMC article.
The quinazolinone unit of the title compound, C(8)H(4)FN(3)O(3), is essentially planar, with a maximum deviation of 0.0538 (14) A for the O atom. The nitro group is twisted by 12.0 (3) from the mean plane of the quinazolinone ring system. The crystal structure is stabilize …
The quinazolinone unit of the title compound, C(8)H(4)FN(3)O(3), is essentially planar, with a maximum deviation of 0.0538 (14) A for …
27,118 results
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