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Type 1 diabetes risk genes mediate pancreatic beta cell survival in response to proinflammatory cytokines.
Benaglio P, Zhu H, Okino ML, Yan J, Elgamal R, Nariai N, Beebe E, Korgaonkar K, Qiu Y, Donovan MKR, Chiou J, Wang G, Newsome J, Kaur J, Miller M, Preissl S, Corban S, Aylward A, Taipale J, Ren B, Frazer KA, Sander M, Gaulton KJ. Benaglio P, et al. Cell Genom. 2022 Nov 11;2(12):100214. doi: 10.1016/j.xgen.2022.100214. eCollection 2022 Dec 14. Cell Genom. 2022. PMID: 36778047 Free PMC article.
Methotrexate in Italian patients wiTh Rheumatoid Arthritis (MITRA study): an observational study about the use of methotrexate in early RA patients and the adherence to the EULAR 2013 recommendations. A project of the Italian Society for Rheumatology.
Benaglio F, Fornaro M, Montecucco C, Raffeiner B, Di Franco M, Iannuccelli C, Conigliaro P, Lomater C, Govoni M, Silvagni E, Zanetti A, Parisi S, Carrara G, Scirè CA, Iannone F, Caporali R. Benaglio F, et al. Clin Exp Rheumatol. 2021 Sep-Oct;39(5):1077-1084. doi: 10.55563/clinexprheumatol/8uy6vj. Epub 2020 Dec 18. Clin Exp Rheumatol. 2021. PMID: 33338006 Free article.
FOXO1 mitigates the SMAD3/FOXL2C134W transcriptomic effect in a model of human adult granulosa cell tumor.
Secchi C, Benaglio P, Mulas F, Belli M, Stupack D, Shimasaki S. Secchi C, et al. Among authors: benaglio p. J Transl Med. 2021 Feb 27;19(1):90. doi: 10.1186/s12967-021-02754-0. J Transl Med. 2021. PMID: 33639972 Free PMC article.

BACKGROUND: Adult granulosa cell tumor (aGCT) is a rare type of stromal cell malignant cancer of the ovary characterized by elevated estrogen levels. aGCTs ubiquitously harbor a somatic mutation in FOXL2 gene, Cys134Trp (c.402C < G); however, the general molecular effec

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BACKGROUND: Adult granulosa cell tumor (aGCT) is a rare type of stromal cell malignant cancer of the ovary characterized by elevated estroge …
Subtle changes in chromatin loop contact propensity are associated with differential gene regulation and expression.
Greenwald WW, Li H, Benaglio P, Jakubosky D, Matsui H, Schmitt A, Selvaraj S, D'Antonio M, D'Antonio-Chronowska A, Smith EN, Frazer KA. Greenwald WW, et al. Among authors: benaglio p. Nat Commun. 2019 Mar 5;10(1):1054. doi: 10.1038/s41467-019-08940-5. Nat Commun. 2019. PMID: 30837461 Free PMC article.
We quantitatively interrogate these relationships by comparing Hi-C and molecular phenotype data across cell types and haplotypes. ...
We quantitatively interrogate these relationships by comparing Hi-C and molecular phenotype data across cell types and haplotypes. .. …
[The Italian instrument evaluating the nursing students clinical learning quality].
Palese A, Grassetti L, Mansutti I, Destrebecq A, Terzoni S, Altini P, Bevilacqua A, Brugnolli A, Benaglio C, Dal Ponte A, De Biasio L, Dimonte V, Gambacorti B, Fasci A, Grosso S, Mantovan F, Marognolli O, Montalti S, Nicotera R, Randon G, Stampfl B, Tollini M, Canzan F, Saiani L, Zannini L. Palese A, et al. Among authors: benaglio c. Assist Inferm Ric. 2017 Jan-Mar;36(1):41-50. doi: 10.1702/2676.27420. Assist Inferm Ric. 2017. PMID: 28398391 Italian.
The tool developed based upon a) literature, b) validated tools already established among other healthcare professionals, and c) consensus expressed by experts and nursing students, was administered to the eligible students. ...According to the findings, the tool consists …
The tool developed based upon a) literature, b) validated tools already established among other healthcare professionals, and c) cons …
[Validation of the Italian Clinical Learning Environment Instrument (SVIAT):<BR>study protocol].
Palese A, Destrebecq A, Terzoni S, Grassetti L, Altini P, Bevilacqua A, Brugnolli A, Benaglio C, Dalponte A, De Biasio L, Dimonte V, Gambacorti B, Fasci A, Grosso S, Mansutti I, Mantovan F, Marognolli O, Montalti S, Nicotera R, Perli S, Randon G, Stampfl B, Tollini M, Canzan F, Zannini L, Saiani L. Palese A, et al. Among authors: benaglio c. Assist Inferm Ric. 2016 Jan-Mar;35(1):29-35. doi: 10.1702/2228.24018. Assist Inferm Ric. 2016. PMID: 27183424 Italian.
METHODS: The study will be developed in three phases: a) instrument development and pilot phase, b) validation of the psychometric properties of the instrument and c) description of the CLEs as perceived by the students including factors/item confirmed in the validation pr …
METHODS: The study will be developed in three phases: a) instrument development and pilot phase, b) validation of the psychometric propertie …
Target sequencing, cell experiments, and a population study establish endothelial nitric oxide synthase (eNOS) gene as hypertension susceptibility gene.
Salvi E, Kuznetsova T, Thijs L, Lupoli S, Stolarz-Skrzypek K, D'Avila F, Tikhonoff V, De Astis S, Barcella M, Seidlerová J, Benaglio P, Malyutina S, Frau F, Velayutham D, Benfante R, Zagato L, Title A, Braga D, Marek D, Kawecka-Jaszcz K, Casiglia E, Filipovsky J, Nikitin Y, Rivolta C, Manunta P, Beckmann JS, Barlassina C, Cusi D, Staessen JA. Salvi E, et al. Among authors: benaglio p. Hypertension. 2013 Nov;62(5):844-52. doi: 10.1161/HYPERTENSIONAHA.113.01428. Epub 2013 Sep 9. Hypertension. 2013. PMID: 24019403
A case-control study revealed association between hypertension and rs3918226 in the endothelial nitric oxide synthase (eNOS) gene promoter (minor/major allele, T/C allele). We aimed at substantiating these preliminary findings by target sequencing, cell experiments, and a …
A case-control study revealed association between hypertension and rs3918226 in the endothelial nitric oxide synthase (eNOS) gene promoter ( …
Network-guided analysis of genes with altered somatic copy number and gene expression reveals pathways commonly perturbed in metastatic melanoma.
Valsesia A, Rimoldi D, Martinet D, Ibberson M, Benaglio P, Quadroni M, Waridel P, Gaillard M, Pidoux M, Rapin B, Rivolta C, Xenarios I, Simpson AJ, Antonarakis SE, Beckmann JS, Jongeneel CV, Iseli C, Stevenson BJ. Valsesia A, et al. Among authors: benaglio p. PLoS One. 2011 Apr 8;6(4):e18369. doi: 10.1371/journal.pone.0018369. PLoS One. 2011. PMID: 21494657 Free PMC article.