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Page 1
Dihydrobenzisoxazole-4-one compounds are novel selective inhibitors of aldosterone synthase (CYP11B2) with in vivo activity.
Meyers K, Cogan DA, Burke J, Arenas R, Balestra M, Brown NF, Chen Z, Cerny MA, Clifford HE, Colombo F, Fader L, Frederick KS, Guo X, Goldberg D, Hornberger KR, Kugler S, Lord J, Marshall DR, Moss N, Parmentier JH, Richman JR, Schmenk J, Weldon SM, Yu M, Zhang M. Meyers K, et al. Among authors: cerny ma. Bioorg Med Chem Lett. 2018 Mar 1;28(5):979-984. doi: 10.1016/j.bmcl.2017.12.015. Epub 2017 Dec 8. Bioorg Med Chem Lett. 2018. PMID: 29254646
Identification of Glycochenodeoxycholate 3-O-Glucuronide and Glycodeoxycholate 3-O-Glucuronide as Highly Sensitive and Specific OATP1B1 Biomarkers.
Neuvonen M, Hirvensalo P, Tornio A, Rago B, West M, Lazzaro S, Mathialagan S, Varma M, Cerny MA, Costales C, Ramanathan R, Rodrigues AD, Niemi M. Neuvonen M, et al. Among authors: cerny ma. Clin Pharmacol Ther. 2021 Mar;109(3):646-657. doi: 10.1002/cpt.2053. Epub 2020 Oct 18. Clin Pharmacol Ther. 2021. PMID: 32961594 Free PMC article.
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