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Doxycycline at subantimicrobial dose combined with escitalopram reverses depressive-like behavior and neuroinflammatory hippocampal alterations in the lipopolysaccharide model of depression.
Mello BSF, Chaves Filho AJM, Custódio CS, Rodrigues PA, Carletti JV, Vasconcelos SMM, Sousa FCF, Sanders LLO, Macedo DS. Mello BSF, et al. Among authors: custodio cs. J Affect Disord. 2021 Sep 1;292:733-745. doi: 10.1016/j.jad.2021.05.083. Epub 2021 Jun 5. J Affect Disord. 2021. PMID: 34161892
Sex influences in behavior and brain inflammatory and oxidative alterations in mice submitted to lipopolysaccharide-induced inflammatory model of depression.
Mello BSF, Chaves Filho AJM, Custódio CS, Cordeiro RC, Miyajima F, de Sousa FCF, Vasconcelos SMM, de Lucena DF, Macedo D. Mello BSF, et al. Among authors: custodio cs. J Neuroimmunol. 2018 Jul 15;320:133-142. doi: 10.1016/j.jneuroim.2018.04.009. Epub 2018 Apr 14. J Neuroimmunol. 2018. PMID: 29681406
Effects of doxycycline on depressive-like behavior in mice after lipopolysaccharide (LPS) administration.
Mello BS, Monte AS, McIntyre RS, Soczynska JK, Custódio CS, Cordeiro RC, Chaves JH, Vasconcelos SM, Nobre HV Jr, Florenço de Sousa FC, Hyphantis TN, Carvalho AF, Macêdo DS. Mello BS, et al. Among authors: custodio cs. J Psychiatr Res. 2013 Oct;47(10):1521-9. doi: 10.1016/j.jpsychires.2013.06.008. Epub 2013 Jul 6. J Psychiatr Res. 2013. PMID: 23835040 Clinical Trial.
Neonatal Immune Challenge with Lipopolysaccharide Triggers Long-lasting Sex- and Age-related Behavioral and Immune/Neurotrophic Alterations in Mice: Relevance to Autism Spectrum Disorders.
Custódio CS, Mello BSF, Filho AJMC, de Carvalho Lima CN, Cordeiro RC, Miyajima F, Réus GZ, Vasconcelos SMM, Barichello T, Quevedo J, de Oliveira AC, de Lucena DF, Macedo DS. Custódio CS, et al. Mol Neurobiol. 2018 May;55(5):3775-3788. doi: 10.1007/s12035-017-0616-1. Epub 2017 May 23. Mol Neurobiol. 2018. PMID: 28536974