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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1988 4
1990 1
1991 2
1992 2
1993 1
1994 4
1996 1
1997 2
1998 1
1999 4
2000 2
2001 1
2002 1
2003 2
2005 1
2006 2
2007 5
2008 7
2009 2
2010 5
2011 6
2012 4
2013 4
2014 3
2015 5
2016 3
2017 1
2019 2
2020 1
2021 1
2022 3
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72 results
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Page 1
Safety, tolerability, and pharmacokinetics of single- and multiple-dose administration of islatravir (MK-8591) in adults without HIV.
Matthews RP, Ankrom W, Friedman E, Jackson Rudd D, Liu Y, Mogg R, Panebianco D, De Lepeleire I, Petkova M, Grobler JA, Stoch SA, Iwamoto M. Matthews RP, et al. Among authors: de lepeleire i. Clin Transl Sci. 2021 Sep;14(5):1935-1944. doi: 10.1111/cts.13048. Epub 2021 Aug 31. Clin Transl Sci. 2021. PMID: 34463432 Free PMC article. Clinical Trial.
Safety and Pharmacokinetics of Islatravir in Individuals with Severe Renal Insufficiency.
Matthews RP, Cao Y, Patel M, Weissler VL, Bhattacharyya A, De Lepeleire I, Last S, Rondon JC, Vargo R, Stoch SA, Iwamoto M. Matthews RP, et al. Among authors: de lepeleire i. Antimicrob Agents Chemother. 2022 Nov 8:e0093122. doi: 10.1128/aac.00931-22. Online ahead of print. Antimicrob Agents Chemother. 2022. PMID: 36346229 Free article.
The PET tracer [11C]MK-6884 quantifies M4 muscarinic receptor in rhesus monkeys and patients with Alzheimer's disease.
Li W, Wang Y, Lohith TG, Zeng Z, Tong L, Mazzola R, Riffel K, Miller P, Purcell M, Holahan M, Haley H, Gantert L, Hesk D, Ren S, Morrow J, Uslaner J, Struyk A, Wai JM, Rudd MT, Tellers DM, McAvoy T, Bormans G, Koole M, Van Laere K, Serdons K, de Hoon J, Declercq R, De Lepeleire I, Pascual MB, Zanotti-Fregonara P, Yu M, Arbones V, Masdeu JC, Cheng A, Hussain A, Bueters T, Anderson MS, Hostetler ED, Basile AS. Li W, et al. Among authors: de lepeleire i. Sci Transl Med. 2022 Jan 12;14(627):eabg3684. doi: 10.1126/scitranslmed.abg3684. Epub 2022 Jan 12. Sci Transl Med. 2022. PMID: 35020407
Rhinovirus-16 induced temporal interferon responses in nasal epithelium links with viral clearance and symptoms.
Ravi A, Chang M, van de Pol M, Yang S, Aliprantis A, Thornton B, Carayannopoulos LN, Bautmans A, Robberechts M, De Lepeleire I, Singh D, Hohlfeld JM, Sterk PJ, Krug N, Lutter R; U-BIOPRED Study Group. Ravi A, et al. Among authors: de lepeleire i. Clin Exp Allergy. 2019 Dec;49(12):1587-1597. doi: 10.1111/cea.13481. Epub 2019 Oct 31. Clin Exp Allergy. 2019. PMID: 31400236 Free PMC article. Clinical Trial.
Kinetic analysis of the cannabinoid-1 receptor PET tracer [(18)F]MK-9470 in human brain.
Sanabria-Bohórquez SM, Hamill TG, Goffin K, De Lepeleire I, Bormans G, Burns HD, Van Laere K. Sanabria-Bohórquez SM, et al. Among authors: de lepeleire i. Eur J Nucl Med Mol Imaging. 2010 May;37(5):920-33. doi: 10.1007/s00259-009-1340-5. Epub 2009 Dec 24. Eur J Nucl Med Mol Imaging. 2010. PMID: 20033684 Clinical Trial.
Pharmacokinetics of raltegravir in individuals with UGT1A1 polymorphisms.
Wenning LA, Petry AS, Kost JT, Jin B, Breidinger SA, DeLepeleire I, Carlini EJ, Young S, Rushmore T, Wagner F, Lunde NM, Bieberdorf F, Greenberg H, Stone JA, Wagner JA, Iwamoto M. Wenning LA, et al. Clin Pharmacol Ther. 2009 Jun;85(6):623-7. doi: 10.1038/clpt.2009.12. Epub 2009 Mar 11. Clin Pharmacol Ther. 2009. PMID: 19279563 Clinical Trial.
Sputum RNA signature in allergic asthmatics following allergen bronchoprovocation test.
Zuiker RG, Tribouley C, Diamant Z, Boot JD, Cohen AF, Van Dyck K, De Lepeleire I, Rivas VM, Malkov VA, Burggraaf J, Ruddy MK. Zuiker RG, et al. Among authors: de lepeleire i. Eur Clin Respir J. 2016 Jul 13;3:31324. doi: 10.3402/ecrj.v3.31324. eCollection 2016. Eur Clin Respir J. 2016. PMID: 27421833 Free PMC article.
Safety, pharmacokinetics, and antiretroviral activity of islatravir (ISL, MK-8591), a novel nucleoside reverse transcriptase translocation inhibitor, following single-dose administration to treatment-naive adults infected with HIV-1: an open-label, phase 1b, consecutive-panel trial.
Schürmann D, Rudd DJ, Zhang S, De Lepeleire I, Robberechts M, Friedman E, Keicher C, Hüser A, Hofmann J, Grobler JA, Stoch SA, Iwamoto M, Matthews RP. Schürmann D, et al. Among authors: de lepeleire i. Lancet HIV. 2020 Mar;7(3):e164-e172. doi: 10.1016/S2352-3018(19)30372-8. Epub 2020 Jan 3. Lancet HIV. 2020. PMID: 31911147 Clinical Trial.
Characterization of the novel GlyT1 PET tracer [18F]MK-6577 in humans.
Joshi AD, Sanabria-Bohórquez SM, Bormans G, Koole M, De Hoon J, Van Hecken A, Depre M, De Lepeleire I, Van Laere K, Sur C, Hamill TG. Joshi AD, et al. Among authors: de lepeleire i. Synapse. 2015 Jan;69(1):33-40. doi: 10.1002/syn.21782. Epub 2014 Sep 24. Synapse. 2015. PMID: 25196464
Pharmacokinetics, pharmacodynamics, and safety of a prostaglandin D2 receptor antagonist.
Lai E, Wenning LA, Crumley TM, De Lepeleire I, Liu F, de Hoon JN, Van Hecken A, Depré M, Hilliard D, Greenberg H, O'Neill G, Metters K, Gottesdiener KG, Wagner JA. Lai E, et al. Among authors: de lepeleire i. Clin Pharmacol Ther. 2008 Jun;83(6):840-7. doi: 10.1038/sj.clpt.6100345. Epub 2007 Sep 19. Clin Pharmacol Ther. 2008. PMID: 17882161 Clinical Trial.
72 results