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TGM2-mediated histone transglutamination is dictated by steric accessibility.
Lukasak BJ, Mitchener MM, Kong L, Dul BE, Lazarus CD, Ramakrishnan A, Ni J, Shen L, Maze I, Muir TW. Lukasak BJ, et al. Among authors: dul be. Proc Natl Acad Sci U S A. 2022 Oct 25;119(43):e2208672119. doi: 10.1073/pnas.2208672119. Epub 2022 Oct 18. Proc Natl Acad Sci U S A. 2022. PMID: 36256821 Free PMC article.
Small molecule photocatalysis enables drug target identification via energy transfer.
Trowbridge AD, Seath CP, Rodriguez-Rivera FP, Li BX, Dul BE, Schwaid AG, Buksh BF, Geri JB, Oakley JV, Fadeyi OO, Oslund RC, Ryu KA, White C, Reyes-Robles T, Tawa P, Parker DL Jr, MacMillan DWC. Trowbridge AD, et al. Among authors: dul be. Proc Natl Acad Sci U S A. 2022 Aug 23;119(34):e2208077119. doi: 10.1073/pnas.2208077119. Epub 2022 Aug 15. Proc Natl Acad Sci U S A. 2022. PMID: 35969791 Free PMC article.
Oncohistone mutations enhance chromatin remodeling and alter cell fates.
Bagert JD, Mitchener MM, Patriotis AL, Dul BE, Wojcik F, Nacev BA, Feng L, Allis CD, Muir TW. Bagert JD, et al. Among authors: dul be. Nat Chem Biol. 2021 Apr;17(4):403-411. doi: 10.1038/s41589-021-00738-1. Epub 2021 Mar 1. Nat Chem Biol. 2021. PMID: 33649601 Free PMC article.
Histone H3Q5 serotonylation stabilizes H3K4 methylation and potentiates its readout.
Zhao S, Chuh KN, Zhang B, Dul BE, Thompson RE, Farrelly LA, Liu X, Xu N, Xue Y, Roeder RG, Maze I, Muir TW, Li H. Zhao S, et al. Among authors: dul be. Proc Natl Acad Sci U S A. 2021 Feb 9;118(6):e2016742118. doi: 10.1073/pnas.2016742118. Proc Natl Acad Sci U S A. 2021. PMID: 33526675 Free PMC article.